[Translation] A randomized, double-blind, placebo-controlled phase II clinical trial to evaluate the efficacy and safety of HSK39297 tablets in the treatment of primary IgA nephropathy
主要目的
评价 HSK39297 片治疗原发性 IgA 肾病患者的有效性。
次要目的
1. 评价 HSK39297 片对原发性 IgA 肾病患者肾功能指标的影响;
2. 评价 HSK39297 片治疗原发性 IgA 肾病患者的安全性;
3. 评价HSK39297片治疗原发性IgA肾病患者的药代动力学(PK)和药效动力学(PD) 特征。
[Translation] Primary objective
To evaluate the effectiveness of HSK39297 tablets in the treatment of patients with primary IgA nephropathy.
Secondary objectives
1. To evaluate the effect of HSK39297 tablets on renal function indicators in patients with primary IgA nephropathy;
2. To evaluate the safety of HSK39297 tablets in the treatment of patients with primary IgA nephropathy;
3. To evaluate the pharmacokinetic (PK) and pharmacodynamic (PD) characteristics of HSK39297 tablets in the treatment of patients with primary IgA nephropathy.