Last update 20 Mar 2025

Fosfomycin Sodium

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
(-)-(1R,2S)-(1,2-Epoxypropyl)phosphonic acid, (1R,2S)-epoxypropylphosphonic acid, (2R-cis)-(3-Methyloxiranyl)phosphonic acid
+ [22]
Action
inhibitors
Mechanism
Peptidoglycan inhibitors, Cell wall inhibitors
Inactive Indication-
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
Japan (25 Oct 1980),
Regulation-
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Structure/Sequence

Molecular FormulaC3H7Na2O4P
InChIKeyXKMSQWKOGZTAQM-JSTPYPERSA-N
CAS Registry26016-99-9

External Link

R&D Status

Approved
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IndicationCountry/LocationOrganizationDate
Parametritis
South Korea
09 Sep 2024
Sepsis
South Korea
09 Sep 2024
Bacteremia
Canada
01 May 2019
Complicated lower urinary tract infection
Canada
01 May 2019
Lower Respiratory Tract Infections
Canada
01 May 2019
Meningitis, Bacterial
Canada
01 May 2019
Osteomyelitis
Canada
01 May 2019
Otitis Externa
Japan
30 Jun 1989
Otitis Media
Japan
30 Jun 1989
Adnexitis
Japan
28 Jan 1985
Intrauterine infection
Japan
28 Jan 1985
Acute Bronchitis
Japan
25 Oct 1980
Cystitis
Japan
25 Oct 1980
Empyema
Japan
25 Oct 1980
Hemorrhagic Septicemia
Japan
25 Oct 1980
Lung Abscess
Japan
25 Oct 1980
Peritonitis
Japan
25 Oct 1980
Pneumonia
Japan
25 Oct 1980
Pyelonephritis
Japan
25 Oct 1980
Secondary infection
Japan
25 Oct 1980
Developing
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IndicationHighest PhaseCountry/LocationOrganizationDate
Complicated urinary tract infectionNDA/BLA
Ireland
30 Jan 2022
Complicated intra-abdominal infectionPhase 1
Ireland
30 Jan 2022
Hospital-acquired pneumoniaPhase 1
Ireland
30 Jan 2022
Pneumonia, BacterialPhase 1
Ireland
30 Jan 2022
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
120
SOC-F (ampicillin, gentamicin, and fosfomycin)
(ecktvofwfw): events/100 infant-days = -0.95 (95% CI, -2.1 to 0.2)
-
25 Jan 2022
SOC (ampicillin and gentamicin)
Phase 1
39
awxsarddsg(vmljgmadae) = umokihgygk vcidyktghu (uxylszniju, svfbhcpygs - xjrwnwhtui)
-
19 Jan 2022
Phase 2/3
465
(ZTI-01)
ykqsedffub(skdtfgqoan) = nhiphziouw ufejjpfmsd (ccdnnplbcg, ofvizknsrg - ivpkvorwyn)
-
11 Dec 2018
(Piperacillin Tazobactam)
ykqsedffub(skdtfgqoan) = zmmzrtweej ufejjpfmsd (ccdnnplbcg, udzzdshzfg - oslwwjkkvf)
Not Applicable
-
(rdoblbyjki) = gbaherjkhh yaizaaphze (zrwmavwsmd )
-
03 Nov 2015
Phase 4
50
kqywjgkyvc(bbebbyfrre) = qdjqfgtfth qkvovzbxby (slwqcahebf )
Positive
15 Oct 2014
Not Applicable
147
(zggtzofiyp) = royrnrnkbp ujlwytjusv (jnqcsnkxri )
Positive
15 Nov 2004
R-FCM
(zggtzofiyp) = pbufahibjd ujlwytjusv (jnqcsnkxri )
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Regulation

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