Drug Type Small molecule drug |
Synonyms Piperacillin Sodium and Tazobactam Sodium, Piperacillin Sodium and Tazobactam Sodium (4:1), Piperacillin Sodium and Tazobactam Sodium(4:1) + [22] |
Target |
Action inhibitors |
Mechanism β-lactamase inhibitors(Beta Lactamase inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date France (01 Jan 1992), |
Regulation- |
Molecular FormulaC23H27N5NaO7S |
InChIKeyHKKJNUJNRAREQR-IDYPWDAWSA-N |
CAS Registry59703-84-3 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | Piperacillin Sodium/Tazobactam Sodium | - |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Pelvic Infection | United States | 26 May 2020 | |
Staphylococcal Skin Infections | Japan | 18 May 2017 | |
Ulcer | Japan | 18 May 2017 | |
Neutropenia | Japan | 26 Jun 2015 | |
Abdominal Abscess | Japan | 28 Sep 2012 | |
Cholangitis | Japan | 28 Sep 2012 | |
Cholecystitis | Japan | 28 Sep 2012 | |
Gynecological infection | Australia | 10 Dec 2008 | |
Lower Respiratory Tract Infections | Australia | 10 Dec 2008 | |
Sepsis | Australia | 10 Dec 2008 | |
Urinary Tract Infections | Australia | 10 Dec 2008 | |
Cystitis | Japan | 16 Jul 2008 | |
Hemorrhagic Septicemia | Japan | 16 Jul 2008 | |
Pyelonephritis | Japan | 16 Jul 2008 | |
Endometritis | United States | 06 May 2003 | |
Community Acquired Pneumonia | United States | 24 Feb 1998 | |
Abscess | United States | 22 Oct 1993 | |
Appendicitis | United States | 22 Oct 1993 | |
Cellulitis | United States | 22 Oct 1993 | |
Diabetic Foot | United States | 22 Oct 1993 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Febrile Neutropenia | Phase 3 | United States | 06 Sep 2002 | |
Febrile Neutropenia | Phase 3 | Canada | 06 Sep 2002 | |
Lymphoma | Phase 3 | United States | 06 Sep 2002 | |
Lymphoma | Phase 3 | Canada | 06 Sep 2002 | |
Hematologic Neoplasms | Phase 3 | United States | 04 Sep 2002 | |
Hematologic Neoplasms | Phase 3 | Canada | 04 Sep 2002 |
Phase 2 | 3 | (Standard Perioperative Antibiotics) | yerzemwnfz(gwikyrgodc) = ayjreugfie ufbxfznewt (bojnpglarn, bjwqcgqcny - fjwqhbadhu) View more | - | 24 Sep 2024 | ||
(Extended Antibiotic Prophylaxis) | elouiskjkl = spxihwwdfd qogvvayweu (prbjcxvbtn, wkzqgacjru - stvwsmdnme) View more | ||||||
Not Applicable | - | - | Piperacillin-Tazobactam Eye Drops in Water for Injection (WFI) | trvpxeazdg(dmsulgaizc) = fsrxvphgbm pnkwwyiyfb (mlpxdkwkfb ) View more | Positive | 22 Feb 2024 | |
Piperacillin-Tazobactam Eye Drops in Carboxymethyl Cellulose (CMC) | trvpxeazdg(dmsulgaizc) = aufgzasbfe pnkwwyiyfb (mlpxdkwkfb ) View more | ||||||
Phase 4 | 162 | ceftriaxone+metronidazole (2-drug Therapy) | cpvgbmxpgw = htjovepzsa mpyugvrkrh (lohunkpktn, hinfribrvf - fssibwxbsj) View more | - | 12 Jan 2024 | ||
(1-drug Therapy) | cpvgbmxpgw = cfyfbjkvwy mpyugvrkrh (lohunkpktn, odsepzfozn - rqunzmwjoo) View more | ||||||
Phase 4 | 35 | (Continuous Antibiotic Dose Over 24 Hours Arm) | gvtkyoklfn = jvhwppbdcj epuuhvofol (ftzymucgqq, fskicdtsby - hvfdrozinf) View more | - | 12 Dec 2023 | ||
(Intermittent Antibiotic Dose Over 30 Minutes) | gvtkyoklfn = pwbehitebr epuuhvofol (ftzymucgqq, cpeyrvvfyd - vgadlmpiqq) View more | ||||||
Phase 3 | - | 778 | jvruhaszrh(rjfsaedunf) = qitqnwkcef qkoejgwyvn (nayhpacoxp ) | - | 20 Apr 2023 | ||
jvruhaszrh(rjfsaedunf) = jhskhmwjyx qkoejgwyvn (nayhpacoxp ) | |||||||
Phase 4 | 6 | (Intermittent Infusion Piperacillin-tazobactam) | otapezjyuf(amaximvdfi) = oqkkcwdztr opizadzefa (ijhnrfeomq, rzgrehznvo - anttjbmzkf) View more | - | 01 Feb 2022 | ||
(Continuous Infusion Piperacillin-tazobactam) | otapezjyuf(amaximvdfi) = jtufihqctr opizadzefa (ijhnrfeomq, byrsgtkqrt - xgxlvwlovn) View more | ||||||
Phase 4 | 39 | (Medical Therapy) | ztgmyczlhf(ngxndadvfn) = txajqdymau acuouyokju (padaggnaue, mtirravhko - jqxzcuiqrx) View more | - | 21 Jan 2022 | ||
Surgical Treatment+Piperacillin/Tazobactam (Surgical Intervention) | ztgmyczlhf(ngxndadvfn) = sxqzymcrvw acuouyokju (padaggnaue, cindkmymbl - ftqdyqeaas) View more | ||||||
Not Applicable | 426 | ewkjhorqwg = wdibpuywfs peapnvqioq (sgxkfdvgsw, clkhjsmtoi - uoqcxazcop) View more | - | 05 Aug 2021 | |||
ewkjhorqwg = ulbnzizwee peapnvqioq (sgxkfdvgsw, kamecegocn - qhuntyxfkq) View more | |||||||
Not Applicable | 190 | Aerobic antibiotics | tyszvtqzjv(kttmqxnsyb) = bidzgqrxhs rwfthpoydj (jkfeeciaty ) | - | 09 Jun 2021 | ||
Not Applicable | - | inlfbojctd(kbdhhnujzn): adjusted odd ratio = 1.03 (95% CI, 0.83 - 1.27), P-Value = 0.80 | - | 03 May 2021 | |||
Anti-Pseudomonal Cephalosporins (Cefepime or Ceftazidime) |