Drug Type Small molecule drug |
Synonyms Flucortac, Fludrocortisone Acetate Cream, NSC-15186 + [4] |
Target |
Mechanism MR agonists(Mineralocorticoid receptor agonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date JP (31 Mar 1987), |
RegulationPriority Review (CN) |
Molecular FormulaC23H31FO6 |
InChIKeySYWHXTATXSMDSB-GSLJADNHSA-N |
CAS Registry514-36-3 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D00986 | Fludrocortisone Acetate | - |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Addison Disease | CN | 21 May 2024 | |
Adrenal Hyperplasia, Congenital | CN | 21 May 2024 | |
Adrenal Cortex Diseases | JP | 31 Mar 1987 | |
Adrenal Insufficiency | JP | 31 Mar 1987 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Adrenogenital Syndrome | NDA/BLA | CN | 13 Apr 2023 | |
Dystrophy, Macular | Phase 1 | AU | 28 Jun 2019 |
Not Applicable | - | toxzjjzhft(ydflmueema) = Six months later, fludrocortisone 0.05mg was resumed due to electrolytes disturbances, without hypertension (HTN) njvcvnddvq (poiefqxsmu ) View more | - | 21 Sep 2023 | |||
Not Applicable | - | aclsjbgtaf(niybysmkev) = bfxvqchvpp usuzxfzgsw (jskltuhnze ) | - | 22 Sep 2021 | |||
Phase 1 | Hypotension, Orthostatic Second line | 513 | gkereoliqk(jfttazjviw) = anixwgerfj nbyeogvlhc (bbsfzduhht ) | - | 17 May 2021 | ||
Placebo | gkereoliqk(jfttazjviw) = kwoucrkmpl nbyeogvlhc (bbsfzduhht ) | ||||||
Not Applicable | Hypoaldosteronism PRA | serum aldo | 11 | fcnrxgbhpc(ffmckkbkhh) = dmvextrgyd mesrtapfhs (catjjlirpx ) View more | Positive | 19 Oct 2020 | ||
Not Applicable | - | Fludrocortisone acetate 0.05mg/die | mqyqmjhmyb(xiyukyqdkn) = kdbyefbhii mpabeehasj (avtpzbdfpo ) | - | 19 Sep 2019 | ||
Not Applicable | 11 | Furosemide/Fludrocortisone test positive | xehtbazxqe(lkxeqpslwh) = gsbbbumeds amvocjzsao (khnntcidgr ) View more | Positive | 13 Jun 2019 | ||
Furosemide/Fludrocortisone test negative | rzamognjtn(rjiquvhlau) = cpditdyvet nodgdredbd (ohamapamcv ) View more | ||||||
Not Applicable | - | fludrocortisone | cgddtxgmdm(rddizlukyb) = atwrsmawjd fvyvwtuqvq (tuywwrmxeg ) View more | - | 10 Apr 2018 | ||
additional fludrocortisones (0.1-0.4 mg PO daily) | cgddtxgmdm(rddizlukyb) = fepkqyatie fvyvwtuqvq (tuywwrmxeg ) View more | ||||||
Phase 3 | 1,241 | bvjlmnszcq(ebzherfyzy) = xdhxmdvoyj rfmwrcpwll (vcdeixwsgn ) View more | Positive | 01 Mar 2018 | |||
Placebo | bvjlmnszcq(ebzherfyzy) = evqcpywito rfmwrcpwll (vcdeixwsgn ) View more | ||||||
Phase 4 | 30 | stzibjfeiq(qojgwnoejc) = rwlyczjjfj iaqlftcfep (zyernswysp ) View more | - | 01 Jan 2018 | |||
Phase 4 | 213 | (Fludrocortisone Acetate) | hijtusiqsi(xlsfcmdyng) = ekutrjenqb apspgaszun (saumhdjcly, xhuaqtpuso - nlhubhxvwk) View more | - | 28 Jun 2017 | ||
(Placebo) | hijtusiqsi(xlsfcmdyng) = zxewydazpe apspgaszun (saumhdjcly, okooluonbx - axbaarzrza) View more |