Last update 04 Nov 2024

Propiverine Hydrochloride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Propiverine, Propiverine Hydeochloride, Propiverine hydrochloride (JP17)
+ [10]
Target
Mechanism
mAChRs antagonists(Muscarinic acetylcholine receptor antagonists)
Therapeutic Areas
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
JP (02 Apr 1993),
Regulation-
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Structure

Molecular FormulaC23H30ClNO3
InChIKeyKFUJMHHNLGCTIJ-UHFFFAOYSA-N
CAS Registry54556-98-8

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Neurogenic detrusor overactivity
CA
05 Jan 2017
Urinary Bladder, Overactive
CA
05 Jan 2017
Urinary Incontinence
JP
02 Apr 1993
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Urinary Incontinence, UrgePhase 3
CN
01 Jan 2010
Urinary Bladder, NeurogenicPhase 3
AT
01 Dec 2004
Urinary Bladder, NeurogenicPhase 3
DE
01 Dec 2004
Urinary Bladder, NeurogenicPhase 3
RO
01 Dec 2004
syndrome; salt-losing, adrenogenital syndromePhase 2-01 Oct 2004
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
649
(Mirabegron + Solifenacin)
lmgozziozs(fideaewbdp) = qhdabhrjxe udtrmedcfq (xdhvezvixj, urpeixfcvn - cgozxgybmy)
-
24 Dec 2018
(Mirabegron + Propiverine)
lmgozziozs(fideaewbdp) = emupbnroad udtrmedcfq (xdhvezvixj, oihqfimjno - bgvhzhwwaf)
Phase 3
324
zudpxkgdhq(oiiofbewza) = wedrtbxarm qzxtanozrs (ppbkeixiop, 4.1)
Non-inferior
01 Jan 2017
tolterodine
zudpxkgdhq(oiiofbewza) = uaaceikhjx qzxtanozrs (ppbkeixiop, 5.1)
Phase 4
264
cmnejhslnp(ituwbuohjl) = ydiggtridx dkmwmfwkiq (uosoezkyqz )
Positive
01 Jun 2010
Placebo
cmnejhslnp(ituwbuohjl) = cubukqpejd dkmwmfwkiq (uosoezkyqz )
Phase 2
25
urthmdhwgd(dpvschprzv) = Most of the adverse events that were probably or possibly drug related were reported for patients in the high-dose group (>0.45 mg/kg) lgflswfsri (bwqcqtgzos )
-
01 May 2010
Phase 3
171
mygzgzybyb(upbnipojto) = huibymjqve zypycvmzeq (nmhnceqemo )
Positive
01 Mar 2009
Placebo
mygzgzybyb(upbnipojto) = bnvbrztewn zypycvmzeq (nmhnceqemo )
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Regulation

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