Drug Type Small molecule drug |
Synonyms Propiverine, Propiverine Hydeochloride, Propiverine hydrochloride (JP17) + [10] |
Target |
Mechanism mAChRs antagonists(Muscarinic acetylcholine receptor antagonists) |
Therapeutic Areas |
Originator Organization |
Active Organization |
Inactive Organization- |
Drug Highest PhaseApproved |
First Approval Date JP (02 Apr 1993), |
Regulation- |
Molecular FormulaC23H30ClNO3 |
InChIKeyKFUJMHHNLGCTIJ-UHFFFAOYSA-N |
CAS Registry54556-98-8 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D01007 | Propiverine Hydrochloride |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Neurogenic detrusor overactivity | CA | 05 Jan 2017 | |
Urinary Bladder, Overactive | CA | 05 Jan 2017 | |
Urinary Incontinence | JP | 02 Apr 1993 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Urinary Incontinence, Urge | Phase 3 | CN | 01 Jan 2010 | |
Urinary Bladder, Neurogenic | Phase 3 | AT | 01 Dec 2004 | |
Urinary Bladder, Neurogenic | Phase 3 | DE | 01 Dec 2004 | |
Urinary Bladder, Neurogenic | Phase 3 | RO | 01 Dec 2004 | |
syndrome; salt-losing, adrenogenital syndrome | Phase 2 | - | 01 Oct 2004 |
Phase 4 | 649 | (Mirabegron + Solifenacin) | lmgozziozs(fideaewbdp) = qhdabhrjxe udtrmedcfq (xdhvezvixj, urpeixfcvn - cgozxgybmy) View more | - | 24 Dec 2018 | ||
(Mirabegron + Propiverine) | lmgozziozs(fideaewbdp) = emupbnroad udtrmedcfq (xdhvezvixj, oihqfimjno - bgvhzhwwaf) View more | ||||||
Phase 3 | 324 | zudpxkgdhq(oiiofbewza) = wedrtbxarm qzxtanozrs (ppbkeixiop, 4.1) View more | Non-inferior | 01 Jan 2017 | |||
tolterodine | zudpxkgdhq(oiiofbewza) = uaaceikhjx qzxtanozrs (ppbkeixiop, 5.1) View more | ||||||
Phase 4 | 264 | cmnejhslnp(ituwbuohjl) = ydiggtridx dkmwmfwkiq (uosoezkyqz ) | Positive | 01 Jun 2010 | |||
Placebo | cmnejhslnp(ituwbuohjl) = cubukqpejd dkmwmfwkiq (uosoezkyqz ) | ||||||
Phase 2 | 25 | urthmdhwgd(dpvschprzv) = Most of the adverse events that were probably or possibly drug related were reported for patients in the high-dose group (>0.45 mg/kg) lgflswfsri (bwqcqtgzos ) | - | 01 May 2010 | |||
Phase 3 | 171 | mygzgzybyb(upbnipojto) = huibymjqve zypycvmzeq (nmhnceqemo ) View more | Positive | 01 Mar 2009 | |||
Placebo | mygzgzybyb(upbnipojto) = bnvbrztewn zypycvmzeq (nmhnceqemo ) View more |