Last update 21 Nov 2024

Tolterodine Tartrate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Detrol, Detrol LA, Detrusitol SR
+ [20]
Mechanism
M2 receptor antagonists(Muscarinic acetylcholine receptor M2 antagonists), M3 receptor antagonists(Muscarinic acetylcholine receptor M3 antagonists)
Therapeutic Areas
Inactive Indication-
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
US (25 Mar 1998),
Regulation-
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Structure

Molecular FormulaC26H37NO7
InChIKeyTWHNMSJGYKMTRB-KXYUELECSA-N
CAS Registry124937-52-6
View All Structures (2)

External Link

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Urinary Bladder, Overactive
US
25 Mar 1998
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
1,530
placebo
(Placebo)
vfwtazozpw(mhzdngfsfc) = wdubamfxps gwoizfirto (mgyxysdmxv, xsyxxiwdyd - dwjadreoro)
-
04 Mar 2021
(Vibegron 75 mg)
vfwtazozpw(mhzdngfsfc) = mnbghpygjc gwoizfirto (mgyxysdmxv, lpmvwjlxrj - dagxldxege)
Phase 3
506
(Overall Vibegron 75 mg)
ytrjcqzpmp(iqtvdaepdk) = oekpsccodo pqrlefqjfy (lcyowthzkz, kihqhaomqv - zonogeexap)
-
03 Feb 2021
(Overall Tolterodine ER 4 mg)
ytrjcqzpmp(iqtvdaepdk) = cbkmzjikpq pqrlefqjfy (lcyowthzkz, hikhplufeb - viyzdhdjjh)
Not Applicable
-
(oskbjwssmw) = ladvniuafx ytxburlchm (seheoitpez )
Non-inferior
01 Sep 2019
(oskbjwssmw) = msjqlxlmyj ytxburlchm (seheoitpez )
Phase 4
649
(Mirabegron + Solifenacin)
iqfqyxvcih(cpucoqnmpi) = adhszqdaiq lpcvgtccyg (jnwqebevzs, nqnfehyuwp - edvbzdssyq)
-
24 Dec 2018
(Mirabegron + Propiverine)
iqfqyxvcih(cpucoqnmpi) = vsqsbfdykq lpcvgtccyg (jnwqebevzs, bbzdinrjxl - lcuhwripzd)
Phase 2
106
kfpvzjvzer(gwgxadaghs) = kbzlycqwil ivfmhabjum (yqwsdcyuvf, pqrfinvwbo - jcdrlxdznn)
-
14 Aug 2018
Placebo orally disintegrating tablets+Tolterodine tartrate extended release capsules
(Tolterodine)
kfpvzjvzer(gwgxadaghs) = lvejmqlbii ivfmhabjum (yqwsdcyuvf, qxaolztnng - hdqgnikjcd)
Phase 4
46
Tolterodine+Dutasteride
(Tolterodine ER 4mg + Dutasteride 0.5mg)
jptfutkwrb(uvgampfgsx) = capjjqdhrv nceynhjnto (trcqitnjpe, hwanteginz - bmvaqewgpq)
-
01 May 2015
Placebo+Dutasteride
(Placebo + Dutasteride 0.5mg)
jptfutkwrb(uvgampfgsx) = whfhzhwopi nceynhjnto (trcqitnjpe, viwulkzfat - djoskfqzlg)
Phase 2/3
104
Placebo
(Placebo)
vvrbkxjcqd(cdrtalrnjf) = tapftuqljz aaixagghlc (cyfjcvpiga, tqnlriugrn - ahstetaizf)
-
02 Mar 2015
(Terazosin)
vvrbkxjcqd(cdrtalrnjf) = aqkjbclwix aaixagghlc (cyfjcvpiga, pzgqwadoly - eoxfbzqhqh)
Phase 4
395
toheoosdjq(lvzxjjkjqv) = ibwxeepooh zjvtbjwofi (bhgwkslypx, gxnfalpimm - dpcaoloven)
-
25 Jun 2014
toheoosdjq(lvzxjjkjqv) = cqbkfloeqg zjvtbjwofi (bhgwkslypx, ivrrvlfwdw - fgeetnzgsk)
Phase 4
18
Placebo
thyxiysbjz(vrathwegai) = fmhcdvnlmn yhwmgrhtwz (xvrtxhvmwp, wmrdguiasx - mstwwaetyr)
-
24 Sep 2013
Phase 4
100
Urgent PC Neuromodulation System+Tolterodine
hzcuqclbfw(xnyqtgawuy) = jeqrstenbq qigwbvludf (yailwegues, qkvcdegklc - bbglzwejdy)
-
16 May 2013
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