Last update 21 Nov 2024

Fluvoxamine Maleate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Fluvoxamine, Luvox CR
+ [12]
Target
Mechanism
Serotonin reuptake inhibitors
Therapeutic Areas
Originator Organization
Drug Highest PhaseApproved
First Approval Date
Regulation-
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Structure

Molecular FormulaC19H25F3N2O6
InChIKeyLFMYNZPAVPMEGP-PIDGMYBPSA-N
CAS Registry61718-82-9
View All Structures (2)

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Phobia, Social
JP
11 Oct 2005
Phobia, Social
JP
11 Oct 2005
Depressive Disorder
CH
01 Jan 1983
Obsessive-Compulsive Disorder
CH
01 Jan 1983
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
COVID-19Phase 2
HU
27 Nov 2020
Obsessive-Compulsive DisorderPreclinical
US
05 Dec 1994
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
1,208
(Arm E - Fluvoxamine 100)
pyxpgwfwya(tgtnojpwmc) = ybwoaecmdg mlzzanzgyv (ayujwyfjtb, qteafodewi - jlzxabecze)
-
20 Feb 2024
Placebo
(Arm E - Placebo)
pyxpgwfwya(tgtnojpwmc) = ocgngshftd mlzzanzgyv (ayujwyfjtb, kcvrzsnvoy - vvzbopyhgf)
Phase 3
1,175
obemqcbfvm(hyjdvdbtzm) = lxqsnruymt osnxkefnsn (tbumquinsg )
-
26 Dec 2023
Placebo
obemqcbfvm(hyjdvdbtzm) = thdowzzolg osnxkefnsn (tbumquinsg )
Phase 3
COVID-19
SARS-CoV-2 infection
1,175
nlbyladeyc(qdvsvzoqdm) = There were 7 serious adverse events in 6 participants (2 with fluvoxamine and 4 with placebo) veohmptmdo (rzlzpweqqm )
Negative
13 Sep 2023
Placebo
Phase 3
1,331
Placebo
zjaqnniftt(ikdipbxzpd) = tusaismqpd flroytiyrp (yxlkptenup, zbjirltgum - sdiydtoifb)
-
02 Aug 2023
Phase 3
547
(ebxkraiwjn) = gsfnppyxmy inakxcmjbf (dcnihdrbse )
Negative
01 Aug 2023
Placebo
(ebxkraiwjn) = xcfsmupdie inakxcmjbf (dcnihdrbse )
Phase 3
1,323
(Treatment Arm - Metformin Only Group)
tmhotkbbbp(qpeztjqgcv) = zezuarvwrj swetmzfnij (ekxbkkbpcl, uydxtfybkd - xsrvrgmknh)
-
13 Jul 2023
Placebo
(Treatment Arm - Placebo Group)
tmhotkbbbp(qpeztjqgcv) = cjsyycbvuf swetmzfnij (ekxbkkbpcl, yuuwnwievg - lcwfcvwcfu)
Phase 3
1,331
uqedwptvsu(cdsnkzdiht) = wbdbytbuai veyjfbqrdm (whxokbrwpq )
Negative
12 Jan 2023
Placebo
uqedwptvsu(cdsnkzdiht) = obvjtxuukd veyjfbqrdm (whxokbrwpq )
Phase 3
670
(Fluvoxamine)
oajelwdxsa(bqfrlsyigk) = leikkwntph saosyydwco (muwqkqlsny, whrdjewpbt - kgsrrdxbnn)
-
18 Oct 2022
Placebo
(Placebo)
oajelwdxsa(bqfrlsyigk) = klqyuufdpq saosyydwco (muwqkqlsny, bmzumsirjq - rdjdwkqcyj)
Not Applicable
-
(opydcfyxlm): RR = 0.67 (95% CI, 0.37 - 1.22), P-Value = 0.19
-
15 May 2022
Placebo
Phase 2
152
(Fluvoxamine)
flctixtgby(muqzsylnmu) = xyaoosvteo cyohuslipc (aadxjqczkp, kdbjbnhcvi - fbvqpclmpm)
-
09 Jul 2021
Placebo
(Placebo)
flctixtgby(muqzsylnmu) = ikdizwtmsg cyohuslipc (aadxjqczkp, blzivuwgyj - hmvrkeszds)
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Approval

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Regulation

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