Last update 22 Nov 2024

Honokiol

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
HL, HU-002, JRF-101
+ [4]
Mechanism
Akt-1 inhibitors(Serine/threonine-protein kinase AKT inhibitors), ERK1 inhibitors(Extracellular-signal-regulated kinase1 inhibitors), ERK2 inhibitors(Extracellular-signal-regulated kinase 2 inhibitors)
Inactive Indication
Originator Organization
Drug Highest PhasePhase 3
First Approval Date-
RegulationOrphan Drug (US)
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Structure

Molecular FormulaC18H18O2
InChIKeyFVYXIJYOAGAUQK-UHFFFAOYSA-N
CAS Registry35354-74-6

External Link

KEGGWikiATCDrug Bank
-Honokiol--

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Gingival DiseasesPhase 3
US
01 Oct 2007
Malignant glioma of brainPhase 2
CN
30 Jan 2022
MeningiomaPhase 2
CN
30 Jan 2022
Nonalcoholic SteatohepatitisPhase 2
KR
01 Nov 2013
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
-
(NX: sea level normoxia controls)
xdqxooxfnp(akxshvjiue) = zsjqlcnooo nurqignaxw (aoyfbplcfd )
-
19 May 2024
(SH: Sugen/Hypoxia PH group)
xdqxooxfnp(akxshvjiue) = dqxayzyjnw nurqignaxw (aoyfbplcfd )
Not Applicable
-
-
Honokiol 10 uM
wxfevnmddi(xmeiltfmfc) = auejyzrnqr kirevrzqjf (pvogrzyaum )
-
03 Jun 2019
Not Applicable
-
cpikwzkqnv(hceoveutuh) = nifuxysrrs rgxigfvdmz (sutsikbvgf )
-
15 Apr 2011
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Clinical Trial

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Approval

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Regulation

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