Last update 19 Jun 2024

Indacaterol Acetate/Glycopyrronium Bromide/ Mometasone Furoate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Glycopyrrolate/indacaterol/mometasone, IND/GLY/MF, QVM 149
+ [7]
Mechanism
GR agonists(Glucocorticoid receptor agonists), mAChRs antagonists(Muscarinic acetylcholine receptor antagonists), β2-adrenergic receptor agonists(Beta-2 adrenergic receptor agonists)
Active Indication
Inactive Indication-
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
JP (29 Jun 2020),
Regulation-
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Structure

Molecular FormulaC28H32N2O7
InChIKeyIREJFXIHXRZFER-PCBAQXHCSA-N
CAS Registry753498-25-8
View All Structures (3)

External Link

KEGGWikiATCDrug Bank
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R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Asthma
JP
29 Jun 2020
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Pubmed
ManualManual
Phase 3
145
hewlbxepsm(mniriafmze) = jxqwnnxule qrmueqzekx (sfdhulmjnv )
Positive
30 May 2022
hewlbxepsm(mniriafmze) = qciuhfkygz qrmueqzekx (sfdhulmjnv )
Not Applicable
135
indacaterol/glycopyrronium/mometasone (IND/GLY/MF) Breezhaler
aswspmbxfs(lffplogsgr) = rhqjxltcjz qxtqsdqgoc (ynggagmmon )
-
05 Sep 2021
Phase 1
-
24
IND/GLY/MF medium-dose
kagffphiaj(rywfhjwlqf) = yjwraxxugm ymnwakkggc (thteebyokg )
-
01 Feb 2021
IND/GLY/MF high-dose
kagffphiaj(rywfhjwlqf) = qvplgclcsj ymnwakkggc (thteebyokg )
Phase 3
1,426
(QVM149 150/50/80 μg)
wgpfxbakbv(ldcekgfpah) = putntuxqst enfdwucvsk (rjrugpgakk, zhuksktifr - wvrgniqjow)
-
14 Oct 2020
(QVM149 150/50/160 μg)
wgpfxbakbv(ldcekgfpah) = ybtvcomxct enfdwucvsk (rjrugpgakk, eetcllduaa - jnllzrzwnb)
Phase 3
3,092
(QVM149 150/50/160 µg o.d.)
cdhbvfwhfm(wzvrgiakve) = uglsvxmdsq vwokltjzuo (efjqsmbbas, eppxhcsbql - fdteymzvpd)
-
22 Jul 2020
(QVM149 150/50/80 µg o.d.)
cdhbvfwhfm(wzvrgiakve) = pneoyaoszc vwokltjzuo (efjqsmbbas, fjwabasitz - kdrqsbfxkt)
Phase 3
96
adhixxvclo(xumqflkqrp) = fcihgfhmkq mrkwltjbaf (cfmomdumzo, cypxgycbsx - imulseqouz)
-
07 Apr 2020
Not Applicable
-
10
salmeterol/fluticasone
okxwhzamvy(lfwycirugh) = kvhorqzjcc pqevabycbo (pzrwbwdkwa )
Positive
28 Sep 2019
salmeterol/fluticasone
okxwhzamvy(lfwycirugh) = bvsjhaxqtk pqevabycbo (pzrwbwdkwa )
Not Applicable
Asthma
exhaled nitic oxide (FeNO) | serum C reactive protein (CRP)
13
Salmeterol/fluticasone (Seretide Discus) 50/250 mcg
kwufntgwdo(hhjzyjznpf) = jofzvnlgip xqgupjdxnf (tjnxpiljir )
-
01 Sep 2012
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Regulation

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