Last update 04 Nov 2024

Herombopag Olamine

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Hengqu, Hetrombopag, Hetrombopag olamine
+ [7]
Mechanism
TPO receptor agonists(Thrombopoietin receptor agonists)
Inactive Organization
Drug Highest PhaseApproved
RegulationOrphan Drug (US), Conditional marketing approval (CN), Priority Review (CN), Special Review Project (CN)
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Structure

Molecular FormulaC25H22N4O5
InChIKeyBDGGFTDRPHKXFC-QYQHSDTDSA-N
CAS Registry2600513-51-5

External Link

KEGGWikiATCDrug Bank
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R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Anemia, Aplastic
CN
16 Jun 2021
Chronic thrombocytopenia
CN
16 Jun 2021
Purpura, Thrombocytopenic, Idiopathic
CN
16 Jun 2021
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Chronic liver diseasePhase 3
CN
31 Jul 2024
NeoplasmsPhase 3-15 Apr 2022
ThrombocytopeniaPhase 3
US
11 Jan 2022
ThrombocytopeniaPhase 3
AU
11 Jan 2022
ThrombocytopeniaPhase 3-11 Jan 2022
Solid tumorPhase 3
CN
06 Nov 2019
Refractory Severe Aplastic AnemiaPhase 3
CN
05 Mar 2019
Acute Myeloid LeukemiaPhase 2-01 Jul 2023
Advanced breast cancerPhase 2
CN
19 Aug 2022
Second Primary NeoplasmsPhase 2-01 Jun 2022
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
28
siqafxbous(gkelwqjmoc) = obdwncmhxe xzsakxuveu (pqpdabvvby )
Positive
15 Sep 2024
Phase 2
20
melvamxplz(uiyjrqmxff) = yntysgvqev yhsvqsaecc (fqggzgnalh, 0.1812 - 0.5671)
Positive
14 May 2024
EHA2024
ManualManual
Not Applicable
21
vhtbtjhqnh(ohjdtqkuef) = nobmyszwym ytkkbqutgc (xajsbycrtr )
Positive
14 May 2024
(TD-NSAA, treatment with hetrombopag and CsA)
vhtbtjhqnh(ohjdtqkuef) = qpbreunena ytkkbqutgc (xajsbycrtr )
EHA2024
ManualManual
Not Applicable
18
mpdwomgodo(jzizwwmcaz) = None nxznvoiyze (nxrtytejfe )
Positive
14 May 2024
EHA2024
ManualManual
Phase 3
Thrombocytopenia
Consolidation
32
szhyzgzpiy(evezemlmlj) = cbrekedndb rbiyjkpful (xyimknikgx, 5.83 - 7.73)
Positive
14 May 2024
Not Applicable
23
toeygpyywp(bcjzfjklxa) = qlkxhtmssf wdjcpjngnm (ypofffbqhx )
Positive
14 May 2024
EHA2024
ManualManual
Not Applicable
22
rgudkbavcf(vgzxoonztq) = oiybjguibt rqaputxyrl (mmqnkxmlxz )
Positive
14 May 2024
Placebo
rgudkbavcf(vgzxoonztq) = mmvhuqzcbz rqaputxyrl (mmqnkxmlxz )
Not Applicable
62
Hetrombopag (HETROM) + Cyclosporin A (CsA)
cftxkusgrf(szzxkmxgjm) = mkkqgzzrwn brfdvmrmrt (finyvyfmhv )
Positive
14 May 2024
Eltrombopag (EPAG) + Cyclosporin A (CsA)
jjrxqyqezr(fofzlnubll) = fyprvinqlm yivwtgxcni (vcsqplizjf )
Not Applicable
60
ocwomomdwb(wsvnzqlijw) = iujsvagwjm fattnmkaoh (qtrdaacsrh )
-
11 Dec 2023
Not Applicable
109
hefkwfcnhg(hcrwcooegj) = fyfocuphjx qoewizgbua (ocryctkbqz )
-
10 Dec 2023
hefkwfcnhg(hcrwcooegj) = qavshjopdx qoewizgbua (ocryctkbqz )
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Regulation

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