Last update 29 Nov 2024

Entacingene turiparvovec (MeiraGTx)

Overview

Basic Info

Drug Type
AAV based gene therapy
Synonyms
Adenovirus Associated Viral Vector Serotype 8 Containing The Human Cngb3 Gene, Adenovirus associated viral vector serotype 8 containing the human CNGB3 gene - MeiraGTx, Entacingene Turiparvovec
+ [4]
Target
Mechanism
CNGB3 gene stimulants(Cyclic nucleotide-gated cation channel beta-3 gene stimulants)
Inactive Indication
Originator Organization
Drug Highest PhasePhase 2
First Approval Date-
RegulationFast Track (US), Orphan Drug (EU)
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Color Vision DefectsPhase 2
US
03 Jan 2023
Achromatopsia 1Phase 2
US
16 Jan 2017
Achromatopsia 1Phase 2
US
16 Jan 2017
Achromatopsia 1Phase 2
GB
16 Jan 2017
Achromatopsia 1Phase 2
GB
16 Jan 2017
Achromatopsia 3Phase 2
US
16 Jan 2017
Achromatopsia 3Phase 2
US
16 Jan 2017
Achromatopsia 3Phase 2
GB
16 Jan 2017
Achromatopsia 3Phase 2
GB
16 Jan 2017
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1/2
23
(Low Dose AAV - CNGB3)
gmujhgypyd(vkuiiezquk) = ofckopnyta jbqmgylila (ongqvjiacd, xxfifudspv - unqnjdkfkk)
-
08 Mar 2023
(Intermediate Dose AAV-CNGB3)
gmujhgypyd(vkuiiezquk) = freddireai jbqmgylila (ongqvjiacd, bbcniamppl - qdmlismbwf)
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Regulation

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