Last update 26 Apr 2025

Omesdafexor

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
FXR-314, MET-642
Target
Action
agonists
Mechanism
FXR agonists(Bile acid receptor FXR agonists)
Inactive Indication
Originator Organization
Inactive Organization
Drug Highest PhasePhase 2/3
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC34H43N3O3
InChIKeyRPBNLMPTFCTXRQ-RYYHSFPWSA-N
CAS Registry2244440-85-3

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Inflammatory Bowel DiseasesPhase 3-08 Dec 2023
Colitis, UlcerativePhase 2-23 Aug 2023
Nonalcoholic SteatohepatitisPhase 2
United States
03 Mar 2021
Fibrosis, LiverPhase 1-08 Dec 2023
Primary Biliary CholangitisPhase 1-08 Dec 2023
Crohn DiseasePreclinical
United States
09 Jan 2024
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
214
jicjdewvhs(qyzhrwhtsu) = aaopiyapgb hhpnuqrebm (yovkltwded, 3.6)
Positive
20 Nov 2024
jicjdewvhs(qyzhrwhtsu) = ahnplytoqu hhpnuqrebm (yovkltwded, 3.7)
Phase 2
214
mdpakfxurp(wjpetyndhx) = lpkbzqjmxr tclazynpdv (owpvrovgqy, 3.6)
Positive
15 Apr 2024
mdpakfxurp(wjpetyndhx) = gqufzvwphu tclazynpdv (owpvrovgqy, 3.7)
Phase 2
-
wueqoumarl(jiqbmyxwnr) = cbyofghuoq xlhdbqcwnv (wkxabdpzvz )
Positive
06 Dec 2023
Placebo
wueqoumarl(jiqbmyxwnr) = sfcikdfldq xlhdbqcwnv (wkxabdpzvz )
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Core Patent

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Clinical Trial

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Approval

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Regulation

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