Last update 21 Nov 2024

Dienogest

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
17-alpha-Cyanomethyl-17-beta-hydroxy-estra-4,9(10)-dien-3-one, 17alpha-17-Hydroxy-3-oxo-19-norpregna-4,9-diene-21-nitrile, Dienogest (JAN/USAN/INN)
+ [21]
Target
Mechanism
ERs agonists(Estrogen receptors agonists), PR agonists(Progesterone receptor agonists)
Inactive Indication-
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
DE (11 Dec 1991),
Regulation-
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Structure

Molecular FormulaC20H25NO2
InChIKeyAZFLJNIPTRTECV-FUMNGEBKSA-N
CAS Registry65928-58-7

External Link

KEGGWikiATCDrug Bank
D03799Dienogest

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Dysmenorrhea
JP
23 Jan 2020
Adenomyosis
JP
02 Dec 2016
Endometriosis
JP
19 Oct 2007
Menopausal syndrome
DE
31 May 1995
Pregnancy
DE
11 Dec 1991
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
AdenomyosisPhase 3
CN
07 Jun 2023
EndometriosisPhase 3-01 Mar 2004
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
887
cgjngosqjk(vphmmbqbem) = aqiuyrihxq zkzpiwunpj (zmchymhobq )
Positive
02 Feb 2022
Not Applicable
134
(Group A)
esmlgoyrnx(aqxkgsxwqn) = xyrlhrrmcf sgpzixpspe (vbraiyugbj )
Positive
30 Mar 2021
(Group B)
esmlgoyrnx(aqxkgsxwqn) = mpynayywer sgpzixpspe (vbraiyugbj )
Phase 3
220
kjxxxphshu(exfnmioons) = inpdiukrye dxtycsgool (trmddfttcy, 26.54)
Positive
01 Feb 2019
Placebo
kjxxxphshu(exfnmioons) = slfxszkzsj dxtycsgool (trmddfttcy, 31.15)
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Approval

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Regulation

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