Last update 21 Nov 2024

NXP-800

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
N-[5-(2,3-Dihydrobenzo[b][1,4]dioxine-6-carboxamido)-2-fluorophenyl]-2-[(4-ethylpiperazin-1-yl)methyl]quinoline-6-carboxamide
+ [3]
Target
Mechanism
EIF2AK4 stimulants(eukaryotic translation initiation factor 2 alpha kinase 4 stimulants)
Inactive Indication-
Originator Organization
Inactive Organization-
Drug Highest PhasePhase 1
First Approval Date-
RegulationFast Track (US), Orphan Drug (US)
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Structure

Molecular FormulaC32H32FN5O4
InChIKeyUBALMDIKIGDHJW-UHFFFAOYSA-N
CAS Registry1693734-80-3

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Clear cell neoplasm of ovaryPhase 1
GB
31 Dec 2021
Clear cell neoplasm of ovaryPhase 1
US
31 Dec 2021
Endometrioid carcinoma ovaryPhase 1
US
31 Dec 2021
Endometrioid carcinoma ovaryPhase 1
GB
31 Dec 2021
Ovarian clear cell adenocarcinomaPhase 1
GB
31 Dec 2021
Ovarian clear cell adenocarcinomaPhase 1
US
31 Dec 2021
Bile Duct NeoplasmsPhase 1
US
-
Platinum-Resistant, ARID1A-Mutated Ovarian CarcinomaPreclinical
US
31 Dec 2021
Platinum-Resistant, ARID1A-Mutated Ovarian CarcinomaPreclinical
GB
31 Dec 2021
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
18
NXP800 50 mg/day
(upinmhjvyf) = yhzwakngqp lypvsltimg (pvpwjdyuti )
Positive
05 Apr 2024
NXP800 75 mg/day
(shwrggmjkg) = zsnzwgrflt ahcxejohty (jebyeepdlo )
Phase 1
3
(kalevhdxam) = emedtvmurj ebtdydaqzq (fbfkizzidd )
Positive
14 Mar 2024
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Clinical Trial

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Approval

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Regulation

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