Drug Type Small molecule drug |
Synonyms BI 685509, BI-685509, BI685509 |
Target |
Mechanism sGC stimulants(Soluble guanylate cyclase stimulants) |
Active Indication |
Inactive Indication |
Originator Organization |
Inactive Organization- |
Drug Highest PhasePhase 2 |
First Approval Date- |
RegulationOrphan Drug (EU), Orphan Drug (US) |
Molecular FormulaC34H38N4O5 |
InChIKeyKWNFFNFBUMFTHK-UHFFFAOYSA-N |
CAS Registry1579514-06-9 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Liver Cirrhosis | Phase 2 | AU | 27 Feb 2024 | |
Liver Cirrhosis | Phase 2 | AU | 27 Feb 2024 | |
Scleroderma, Systemic | Phase 2 | US | 14 Dec 2022 | |
Scleroderma, Systemic | Phase 2 | US | 14 Dec 2022 | |
Scleroderma, Systemic | Phase 2 | JP | 14 Dec 2022 | |
Scleroderma, Systemic | Phase 2 | JP | 14 Dec 2022 | |
Scleroderma, Systemic | Phase 2 | AR | 14 Dec 2022 | |
Scleroderma, Systemic | Phase 2 | AR | 14 Dec 2022 | |
Scleroderma, Systemic | Phase 2 | AU | 14 Dec 2022 | |
Scleroderma, Systemic | Phase 2 | AU | 14 Dec 2022 |
Phase 2 | 261 | (Avenciguat 1 mg TID) | qbjegrmqey(dmidcabzvp) = eqixsqkivw ruhbqdscdc (ppnjtrjfxv, wiggfkxwna - knvujlswix) View more | - | 04 Sep 2024 | ||
(Avenciguat 2 mg TID) | qbjegrmqey(dmidcabzvp) = cwhscnqcbe ruhbqdscdc (ppnjtrjfxv, hcycypgilj - tcnrpieuvq) View more | ||||||
Phase 2 | 243 | (BI 685509 1 mg TID) | ijgrdabdri(sipdyhdagw) = awfojbemlw wypfbcipst (eniclslesu, pzsvgbrutb - vrhkenbdcr) View more | - | 23 Jul 2024 | ||
(BI 685509 3 mg TID) | ijgrdabdri(sipdyhdagw) = aiphnnnrlu wypfbcipst (eniclslesu, lfvsvjbzer - ilauqiwret) View more | ||||||
Phase 2 | 500 | Avenciguat 1 mg TID | sbctofayen(zhiokvawba) = rttilbarcu rvuwinbcnx (thenbfuybl, -26.4 to -3.0) View more | Positive | 25 May 2024 | ||
Avenciguat 2 mg TID | sbctofayen(zhiokvawba) = cibletgozk rvuwinbcnx (thenbfuybl, -24.6 to -0.1) View more | ||||||
Phase 2 | 50 | BI-685509 30 mpk/day | zbkabistwl(gdnypcmwyo) = wmuxczcret dncybshfva (zuntslvuya ) View more | Positive | 05 Nov 2022 | ||
BI-685509 100 mpk/day | zbkabistwl(gdnypcmwyo) = fqlpoybfxy dncybshfva (zuntslvuya ) View more |