Synonyms Diffuse Cutaneous Systemic Sclerosis, Diffuse Scleroderma, Diffuse Sclerosis + [54] |
Introduction A rapid onset form of SYSTEMIC SCLERODERMA with progressive widespread SKIN thickening over the arms, the legs and the trunk, resulting in stiffness and disability. |
Target |
Mechanism ROCK1 inhibitors [+1] |
Originator Org. |
Active Indication |
Inactive Indication |
Drug Highest PhaseApproved |
First Approval Ctry. / Loc. United States |
First Approval Date16 Jul 2021 |
Target |
Mechanism IGF-1R antagonists |
Active Org. |
Originator Org. |
Active Indication |
Inactive Indication |
Drug Highest PhaseApproved |
First Approval Ctry. / Loc. United States |
First Approval Date21 Jan 2020 |
Target |
Mechanism IL-23p19 inhibitors |
Active Org. |
Originator Org. |
Active Indication |
Inactive Indication |
Drug Highest PhaseApproved |
First Approval Ctry. / Loc. United States |
First Approval Date13 Jul 2017 |
Start Date01 Jul 2025 |
Sponsor / Collaborator |
Start Date29 Apr 2025 |
Sponsor / Collaborator |
Start Date27 Mar 2025 |
Sponsor / Collaborator |