Last update 21 Nov 2024

Enobosarm

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Enobosarm (USAN), Ostarine
+ [3]
Target
Mechanism
AR agonists(Androgen Receptor agonists)
Active Indication
Originator Organization
Active Organization
Inactive Organization
Drug Highest PhasePhase 2
First Approval Date-
RegulationFast Track (US)
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Structure

Molecular FormulaC19H14F3N3O3
InChIKeyJNGVJMBLXIUVRD-SFHVURJKSA-N
CAS Registry841205-47-8

External Link

KEGGWikiATCDrug Bank
D10221Enobosarm-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
CachexiaPhase 2
CL
--
CachexiaPhase 2
UA
--
CachexiaPhase 2
HU
--
CachexiaPhase 2
PE
--
CachexiaPhase 2
PE
--
CachexiaPhase 2
UA
--
CachexiaPhase 2
RU
--
CachexiaPreclinical
HU
--
CachexiaPreclinical
CL
--
CachexiaPreclinical
RU
--
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
ADA2024
ManualManual
Not Applicable
1,027
(xzrzxohjsv) = myukllxiqy pssgcuhqlo (xghopctipw )
Positive
21 Jun 2024
Placebo
(xzrzxohjsv) = okkqmcvkgd pssgcuhqlo (xghopctipw )
ADA2024
ManualManual
Not Applicable
367
Enobosarm 3mg q day
(wjbqjjwevt) = mmozcsvhvx rpfkpcgdfb (lgnssegenn )
Positive
21 Jun 2024
Phase 2/3
-
1,027
(efbiwalvkp) = jpugwemous uulabggscv (myuovnvkbe )
Positive
14 Jun 2024
Placebo
(efbiwalvkp) = pldbpxpsph uulabggscv (myuovnvkbe )
Phase 2
AR Positive/ER Positive/HER2 Negative Breast Cancer
androgen receptor-positive | oestrogen receptor-positive | HER2-negative
102
(wxdesehwpt) = sixfnjmxhg wfkkwngrxh (vktivfpula, 20 - 47)
Positive
25 Mar 2024
(wxdesehwpt) = kkovwxcnwz wfkkwngrxh (vktivfpula, 17 - 43)
Phase 2
18
Laboratory Biomarker Analysis+pembrolizumab+Enobosarm
(soywmehdit) = tmiaaahspy asesymyzbh (znqdgadrio, jwmknkbdso - mtiegqpldq)
-
10 Jun 2022
Phase 2
AR Positive/ER Positive Breast Cancer
AR Positive | ER Positive
10
(pulxermpjz) = jkpvokpfan fmgsdcjyyl (ttqmegnryi )
Positive
05 May 2021
(all)
(memwwtofvs) = kxygoacxjd riqvbajkuu (wphbxmkxro )
AACR2021
ManualManual
Phase 2
AR Positive/ER Positive Breast Cancer
ER Positive | AR Positive
136
(opapzlpqjr) = rzjytrnirg teqidxjtjm (nfglsramav, 19.5 - 46.7)
Positive
15 Feb 2021
(opapzlpqjr) = zhjxxbjazz teqidxjtjm (nfglsramav, 17.1 - 43.1)
Phase 2
Triple Negative Breast Cancer
Triple-Negative | Androgen Receptor-Positive
16
(upxbwnsaus) = one dry skin, one diarrhea, and one musculoskeletal ache. pfzltpkhvd (kbpkvgptnf )
Positive
01 Feb 2021
Phase 2
19
pkwspgweau(wiuksgofxu) = srheyqamsd aarjtmwvbe (jrheqgffxk, takbtfkqar - bfrlcocxga)
-
01 Feb 2021
Phase 2
136
(GTx-024 9 mg)
fbqshpopae(qrnnrcolgx) = hfimkaxflh tdbrzhbphq (jhdmofgnlm, mfoyhjihde - exkhtnrylj)
-
09 Dec 2020
(GTx-024 18 mg)
fbqshpopae(qrnnrcolgx) = svxjgjxqal tdbrzhbphq (jhdmofgnlm, ciftbmideq - yycozcqyis)
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Core Patent

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Clinical Trial

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Approval

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Regulation

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