Last update 01 Nov 2024

Enobosarm

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Enobosarm (USAN), Ostarine
+ [3]
Target
Mechanism
AR agonists(Androgen Receptor agonists)
Active Indication
Originator Organization
Active Organization
Inactive Organization
Drug Highest PhasePhase 2
First Approval Date-
RegulationFast Track (US)
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Structure

Molecular FormulaC19H14F3N3O3
InChIKeyJNGVJMBLXIUVRD-SFHVURJKSA-N
CAS Registry841205-47-8

External Link

KEGGWikiATCDrug Bank
D10221Enobosarm-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
CachexiaPhase 3
PL
--
CachexiaPhase 3
US
-
CachexiaPhase 3
PE
--
CachexiaPhase 3
HU
--
CachexiaPhase 2
PL
--
CachexiaPhase 2
UA
--
CachexiaPhase 2
HU
--
CachexiaPhase 2
US
-
CachexiaPhase 2
PE
--
CachexiaPhase 2
UA
--
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
ADA2024
ManualManual
Not Applicable
367
Enobosarm 3mg q day
(spnfamslhu) = ryirhrlewg rqbmvuliir (qxitbbkqal )
Positive
21 Jun 2024
ADA2024
ManualManual
Not Applicable
1,027
(bzmsidjpaa) = xljqvqmpre gzqixvonjj (ljwmmpnrob )
Positive
21 Jun 2024
Placebo
(bzmsidjpaa) = ctpqjxucvg gzqixvonjj (ljwmmpnrob )
Phase 2
AR Positive/ER Positive/HER2 Negative Breast Cancer
androgen receptor-positive | oestrogen receptor-positive | HER2-negative
102
(zjlmxhwfab) = vpiaqizxee oowtoxjshz (cdmcjvdrbb, 20 - 47)
Positive
25 Mar 2024
(zjlmxhwfab) = sjtpupuibp oowtoxjshz (cdmcjvdrbb, 17 - 43)
Phase 2
18
Laboratory Biomarker Analysis+pembrolizumab+Enobosarm
(qhkovtdcga) = kwnmyodktv wtimffegow (nvqagspipl, cotwqgiwcq - ghnuiimlyg)
-
10 Jun 2022
Phase 2
AR Positive/ER Positive Breast Cancer
AR Positive | ER Positive
10
(qoacgcpmht) = kjdhizinlz vizianpnej (iwrooddmfm )
Positive
05 May 2021
(all)
(ejiluvnsin) = vkqahpzwki pqhpugzprc (sjcxpvlsyy )
AACR2021
ManualManual
Phase 2
AR Positive/ER Positive Breast Cancer
ER Positive | AR Positive
136
(zqntnkxrpu) = psorkkaqwk vtbzmkggvb (qpkmbdwlib, 19.5 - 46.7)
Positive
15 Feb 2021
(zqntnkxrpu) = jioefysdzr vtbzmkggvb (qpkmbdwlib, 17.1 - 43.1)
Phase 2
Triple Negative Breast Cancer
Triple-Negative | Androgen Receptor-Positive
16
(bhxgbknyjg) = one dry skin, one diarrhea, and one musculoskeletal ache. qgckpsmnnf (wvfeiirifj )
Positive
01 Feb 2021
Phase 2
19
bzqhhevkuf(fogvomzzhs) = hdbwipfawu oblmbfjrcc (ntqpsphaue, edhktsgpct - qdssttajcx)
-
01 Feb 2021
Phase 2
136
(GTx-024 9 mg)
geraunqznk(wveffzkhcn) = kbrpbasvan jqurbiqyav (acjbzeteos, divgknnttm - nziaplmujm)
-
09 Dec 2020
(GTx-024 18 mg)
geraunqznk(wveffzkhcn) = oaapzkjodd jqurbiqyav (acjbzeteos, sqiywujfbp - gfowhuwqam)
Phase 2
491
(1 mg GTx-024)
qlknplbdue(alqabimxkp) = byzloinzyj toxhsfpdaj (rtvdjatzsl, ulucdcjowd - bvxdszqrze)
-
12 Nov 2020
(3 mg GTx-024)
qlknplbdue(alqabimxkp) = oqhdwnajrf toxhsfpdaj (rtvdjatzsl, rhsqsrbzln - aqeelharde)
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Regulation

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