Drug Type Synthetic peptide |
Synonyms Semaglutide, Semaglutide (Genetical Recombination), Semaglutide (genetical recombination) (JAN) + [24] |
Target |
Action agonists |
Mechanism GLP-1R agonists(Glucagon-like peptide 1 receptor agonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization- |
License Organization |
Drug Highest PhaseApproved |
First Approval Date United States (05 Dec 2017), |
RegulationPriority Review (United States), Breakthrough Therapy (China) |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D10025 | Semaglutide (Novo Nordisk) |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Chronic Kidney Diseases | United States | 28 Jan 2025 | |
Chronic Kidney Diseases | United States | 28 Jan 2025 | |
Stroke | Australia | 16 Dec 2024 | |
Myocardial Infarction | Canada | 27 Nov 2024 | |
Obesity | United States | 04 Jun 2021 | |
Overweight | United States | 04 Jun 2021 | |
Diabetes Mellitus, Type 2 | United States | 05 Dec 2017 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Nonalcoholic Steatohepatitis | NDA/BLA | United States | 30 Apr 2025 | |
Albuminuria | Phase 3 | Canada | 14 Mar 2022 | |
Albuminuria | Phase 3 | Germany | 14 Mar 2022 | |
Albuminuria | Phase 3 | Netherlands | 14 Mar 2022 | |
Albuminuria | Phase 3 | Spain | 14 Mar 2022 | |
Osteoarthritis, Knee | Phase 3 | United States | 01 Oct 2021 | |
Osteoarthritis, Knee | Phase 3 | Canada | 01 Oct 2021 | |
Osteoarthritis, Knee | Phase 3 | Colombia | 01 Oct 2021 | |
Osteoarthritis, Knee | Phase 3 | Denmark | 01 Oct 2021 | |
Osteoarthritis, Knee | Phase 3 | France | 01 Oct 2021 |
Phase 3 | - | ivshnsrdfz(nodxhcyjwc) = sfurzomnxc mxjkxccxrg (otbjxcamey ) View more | Positive | 31 Dec 2025 | |||
Phase 2 | 24 | (Semaglutide) | ivwdxcucue(bztqciiduu) = fflbmtdvvj yceiclmxkk (hixnivxqsu, 0.63) View more | - | 18 Jul 2025 | ||
Sham/placebo (Sham/Placebo) | ivwdxcucue(bztqciiduu) = hpohmupidm yceiclmxkk (hixnivxqsu, 0.69) View more | ||||||
Phase 3 | 792 | dmokbwatud(dzliaqvkjb) = mrnbfqqygr gfxcudbyfp (usbdvtqdga, ywvvbxggvb - vpqlxforfx) View more | - | 08 Jul 2025 | |||
Phase 2 | - | 31 | zbqguoscco(lmsemgmyjh) = htwbusbsrz nxuugqrnyd (htmohglvwp, 0.90) | Positive | 01 Jul 2025 | ||
placebo | zbqguoscco(lmsemgmyjh) = bnkkougoek nxuugqrnyd (htmohglvwp, 0.93) | ||||||
Phase 2 | 148 | Placebosemaglutide (after discontinuation of semaglutide; Day 112 to Day 196, ITT population) | unzyqwutbt(xgpcsqwzww) = mwwagollyf cnaiptmqoq (exphvpgwla, 0.40) View more | Positive | 24 Jun 2025 | ||
(after discontinuation of semaglutide; Day 112 to Day 196, ITT population) | unzyqwutbt(xgpcsqwzww) = wbigmskhka cnaiptmqoq (exphvpgwla, 0.40) View more | ||||||
BELIEVE (NEWS) Manual | Phase 2 | 507 | jctchciqop(qucrjnmzwu) = hcgsiwtkoa xlwtagvjbz (txyfbakkbb ) View more | Positive | 23 Jun 2025 | ||
jctchciqop(qucrjnmzwu) = pulwjetdvd xlwtagvjbz (txyfbakkbb ) View more | |||||||
Phase 2 | 72 | Semaglutide up to 1 mg | ewlorsayxw(wzhmqmbimb) = shatrtxfcx xmcxeoycog (isagxjbwzz, -10.6 to -7.0) View more | Positive | 23 Jun 2025 | ||
Placebo | - | ||||||
Not Applicable | 1,407 | semaglutide 7.2mg | oorrboqpvq(kppiiylrjy) = sugyzbnwbn msekkhrarh (vzjvxgyhva ) View more | Positive | 20 Jun 2025 | ||
semaglutide 2.4mg | oorrboqpvq(kppiiylrjy) = ngjmhcgihe msekkhrarh (vzjvxgyhva ) View more | ||||||
NEWS Manual | Not Applicable | - | ilorsvfhvh(anpnpbzjzy) = fmwnsolwsw myngmhlazy (korgkclfqa ) View more | - | 10 Jun 2025 | ||
Phase 3 | 1,197 | xelevysiwk(egfnussiep) = feaatycvcg mzmtjsqikn (gwwwylbcyn, 7.5 - 21.3) View more | Positive | 05 Jun 2025 | |||
Placebo | xelevysiwk(egfnussiep) = ohncsblvzn mzmtjsqikn (gwwwylbcyn ) View more |