Drug Type Small molecule drug |
Synonyms |
Target |
Mechanism menin inhibitors(Menin inhibitors) |
Therapeutic Areas |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization- |
Drug Highest PhasePhase 1/2 |
First Approval Date- |
RegulationFast Track (US), Orphan Drug (US) |
Molecular FormulaC33H43FN6O3 |
InChIKeyJQHJEDMMWUIYCE-FVVBACEJSA-N |
CAS Registry2412555-70-3 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Acute Lymphoblastic Leukemia | Phase 2 | IT | 28 Feb 2022 | |
Acute Lymphoblastic Leukemia | Phase 2 | US | 28 Feb 2022 | |
Acute Lymphoblastic Leukemia | Phase 2 | FR | 28 Feb 2022 | |
Acute Lymphoblastic Leukemia | Phase 2 | TW | 28 Feb 2022 | |
Acute Lymphoblastic Leukemia | Phase 2 | SG | 28 Feb 2022 | |
Acute Lymphoblastic Leukemia | Phase 2 | BE | 28 Feb 2022 | |
Acute Lymphoblastic Leukemia | Phase 2 | KR | 28 Feb 2022 | |
Acute Lymphoblastic Leukemia | Phase 2 | ES | 28 Feb 2022 | |
Acute Lymphoblastic Leukemia | Phase 2 | JP | 28 Feb 2022 | |
Adult Acute Myeloblastic Leukemia | Phase 2 | US | 30 Jan 2022 |
NCT04988555 (ASH2024) Manual | Phase 1/2 | 81 | (ovfodviflm) = None egwugnviju (cmebqipzdt ) View more | Positive | 07 Dec 2024 | ||
(KMT2Ar + not received a prior menin inhibitor) | |||||||
NCT04988555 (EHA2024) Manual | Phase 1/2 | 58 | (zcrlghflib) = pbatcnnzyw vgxuvmtvdk (igskcjvrux ) View more | Positive | 14 May 2024 | ||
NCT04988555 (ASH2023) Manual | Phase 1/2 | 24 | DSP-5336±concomitant azole therapy | (rgcygzetbm) = tmhprdbzjx gofbnidcsv (hihsueelle ) View more | Positive | 10 Dec 2023 | |
DSP-5336±concomitant azole therapy (NPM1c) | (banhknmdmy) = furpedhkya vzwscdlscn (aakpzfxnnw ) |