Last update 01 Nov 2024

Ligufalimab

Overview

Basic Info

Drug Type
Monoclonal antibody
Synonyms
ligufalimab
+ [1]
Target
Mechanism
CD47 inhibitors(Cluster of differentiation 47 inhibitors)
Inactive Indication-
Originator Organization
Active Organization
Inactive Organization-
Drug Highest PhasePhase 3
First Approval Date-
Regulation-
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Squamous Cell Carcinoma of Head and NeckPhase 3
CN
11 Sep 2024
Advanced Triple-Negative Breast CarcinomaPhase 2
CN
23 Mar 2022
Metastatic Triple-Negative Breast CarcinomaPhase 2
CN
23 Mar 2022
Adenocarcinoma of EsophagusPhase 2
CN
30 Jan 2022
Rectal CancerPhase 2
CN
30 Jan 2022
stomach adenocarcinomaPhase 2
CN
30 Jan 2022
Advanced cancerPhase 2
CN
18 Jan 2022
Acute Myeloid LeukemiaPhase 2
CN
04 Jun 2021
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
30
Ivonescimab monotherapy
(hoazcslrtz) = frrlfiqzzw ulukyhwnxo (nwfnmryuya )
Positive
14 Sep 2024
(hoazcslrtz) = gsxtnpzqao ulukyhwnxo (nwfnmryuya )
Phase 2
Metastatic Colorectal Carcinoma
First line
KRAS | BRAF | MSS
40
FOLFOXIRI + Ivonescimab
(hqsohqpeiq) = gydajzdasc sojxbbndtz (hliqbmfxvl )
Positive
14 Sep 2024
FOLFOXIRI + Ivonescimab + Ligufalimab
(hqsohqpeiq) = xaibpqqinv sojxbbndtz (hliqbmfxvl )
Phase 1
86
(oqjcnzrybq) = ylmneowbcd bjqbrluzsh (oknexpzjhu )
Positive
09 Dec 2023
Phase 2
16
cadonilimab+AK117+chemotherapy
(bczfltedmv) = oeiwshhxoc sprsoignpi (wrazhitveg )
Positive
26 May 2023
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Approval

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Regulation

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