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Last update 29 Jan 2025
RC-148
Last update 29 Jan 2025
Overview
Basic Info
Drug Type Bispecific antibody |
Synonyms RC 148, RC148 |
Target |
Mechanism PD-1 modulators(Programmed cell death protein 1 modulators), VEGF modulators(Vascular endothelial growth factor modulators) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization- |
Drug Highest PhasePhase 2 |
First Approval Date- |
Regulation- |
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Structure/Sequence
Sequence Code 160581189
Related
6
Clinical Trials associated with RC-148NCT06642545
A Randomized, Open-label, Controlled, Multicenter Phase II Study to Evaluate the Efficacy and Safety of Disitamab Vedotin Combined With RC148 Versus Albumin-bound Paclitaxone Alone or in Combination With Toripalimab in Subjects With HR-negative, HER2-low Expressing Unresectable Locally Advanced or Metastatic Breast Cancer
CTR20243539
评价维迪西妥单抗联合RC148对照白蛋白结合型紫杉醇单药或联合特瑞普利单抗治疗HR阴性HER2低表达的不可切除的局部晚期或转移性乳腺癌受试者有效性和安全性的随机、开放、对照、多中心II期临床研究
[Translation] A randomized, open-label, controlled, multicenter phase II clinical study to evaluate the efficacy and safety of vedicizumab combined with RC148 or nab-paclitaxel alone or combined with toripalimab in the treatment of patients with HR-negative, HER2-low-expressing, unresectable locally advanced or metastatic breast cancer
NCT06016062
A Multi-center Phase I/II Trial to Evaluate the Efficacy and Safety of RC148 As a Single Agent and Combination Therapy in Patients with Locally Advanced Unresectable or Metastatic Malignant Solid Tumors
100 Clinical Results associated with RC-148
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100 Translational Medicine associated with RC-148
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100 Patents (Medical) associated with RC-148
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100 Deals associated with RC-148
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R&D Status
10 top R&D records. to view more data
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| HR-negative/HER2-low Breast Carcinoma | Phase 2 | CN | 17 Feb 2025 | |
| Advanced Malignant Solid Neoplasm | Phase 2 | CN | 07 Sep 2023 | |
| Bile Duct Neoplasms | Phase 2 | CN | 03 Aug 2023 | |
| CLDN18.2 Positive Advanced Malignant Solid Neoplasm | Phase 2 | CN | 03 Aug 2023 | |
| Esophageal Carcinoma | Phase 2 | CN | 03 Aug 2023 | |
| Gastrooesophageal junction cancer | Phase 2 | CN | 03 Aug 2023 | |
| Locally Advanced Malignant Solid Neoplasm | Phase 2 | CN | 03 Aug 2023 | |
| Locally Advanced Unresectable Gastric Adenocarcinoma | Phase 2 | CN | 03 Aug 2023 | |
| Ovarian Cancer | Phase 2 | CN | 03 Aug 2023 | |
| Pancreatic Cancer | Phase 2 | CN | 03 Aug 2023 |
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