Last update 24 May 2024

Equecabtagene Autoleucel

Overview

Basic Info

Drug Type
Autologous CAR-T
Synonyms
Anti-BMCA CAR-T cell therapy, Equ-Cel, Eque-cel
+ [10]
Target
Mechanism
BCMA inhibitors(B-cell maturation protein inhibitors)
Inactive Indication-
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
CN (30 Jun 2023),
RegulationFast Track (US), Orphan Drug (US), Priority Review (CN), Breakthrough Therapy (CN), Conditional marketing approval (CN), Regenerative Medicine Advanced Therapy (US)
Login to view First Approval Timeline

R&D Status

Approved
10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
Multiple Myeloma
CN
30 Jun 2023
Multiple Myeloma
CN
30 Jun 2023
Developing
10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Hashimoto's EncephalitisPhase 1
CN
22 Sep 2020
Idiopathic Inflammatory MyopathiesPhase 1
CN
22 Sep 2020
Multiple SclerosisPhase 1
CN
22 Sep 2020
Myasthenia GravisPhase 1
CN
22 Sep 2020
Myelin oligodendrocyte glycoprotein antibody-associated diseasePhase 1
CN
22 Sep 2020
Neuromyelitis OpticaPhase 1
CN
22 Sep 2020
POEMS SyndromePhase 1
CN
22 Sep 2020
Polyradiculoneuropathy, Chronic Inflammatory DemyelinatingPhase 1
CN
22 Sep 2020
Relapse multiple myelomaIND Approval
CN
28 Mar 2024
AQP4-IgG positive Neuromyelitis optica spectrum disorderIND Approval
CN
19 Aug 2022
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
16
eornxejezk(aluiypkiyi) = jymstrrygg msqvxjwgvq (nvszxmgmjj )
Positive
14 May 2024
Early Phase 1
2
fuknseocau(vbuvvhvros) = vvfzxiayrs kptkbvqvxo (bdgksveslf )
Positive
26 Feb 2024
Early Phase 1
1
mnkxaiowxx(avrbbixqdi) = The patient developed only grade 1 cytokine release syndrome (CRS), but had no immune effector cell-associated neurotoxicity syndrome (ICANS). Only transient hemocytopenia was observed. qzhcprkuon (imoxtldoon )
Positive
30 Jan 2024
Phase 1
18
dwljdkzywe(gwsynkikgi) = The recovery of B cells and globulin were observed in 5 and 15 patients, respectively. But for the seven alive patients with sCR, only two of them had B cell recovered. rezjsvleau (nqqirvudpl )
Positive
11 Dec 2023
Phase 1/2
105
Eque-cel
zzibaciyxj(rhnjqygerf) = kxvwsdjlrr btdnvzqhez (swffuuqifq, 80.07 - 96.92)
Positive
26 Sep 2023
Phase 1/2
103
trmhdmdvjj(svefcdkhzn) = jezypakcfk fjmywjbhnf (fwewnqfnkr )
Positive
26 May 2023
Phase 1
Neuromyelitis Optica
AQP4 Antibody Positive
12
ucnkgfzqji(fjawpvsxka) = xeoiegvkhs pgpffpyphu (scswftmkrl )
Positive
18 Nov 2022
Phase 1/2
103
(the median time to first response was 16 days)
tsiffwycim(zxjfmfpfcj) = 13 of 98 subjects (13.3%) znzykydnzn (ejrknxuajj )
Positive
15 Nov 2022
(subjects who have completed 3-month follow-up)
Phase 1/2
79
Equecabtagene Autoleucel 1.0×10^6 CAR+ T cells/kg+cyclophosphamide 500 mg/m^2+fludarabine 30 mg/m^2
zdnmzxgneq(burkdputmw) = ffvymtufli qyouzpizje (qitgvdpvcp )
Positive
12 May 2022
Phase 1
35
obyekrudgy(vlhmaerqiw) = iuhmelqpyo aveghlnjyg (tucepafujp )
-
09 Jun 2021
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Leverages most recent intelligence information, enabling fullest potential.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free