Last update 21 Nov 2024

Sapacitabine

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Sapacitabine (USAN/INN)
Mechanism
CDK2 inhibitors(Cyclin-dependent kinase 2 inhibitors), CDK9 inhibitors(Cyclin-dependent kinase 9 inhibitors)
Originator Organization
Inactive Organization
Drug Highest PhasePhase 3
First Approval Date-
RegulationOrphan Drug (EU)
Login to view timeline

Structure

Molecular FormulaC26H42N4O5
InChIKeyLBGFKUUHOPIEMA-PEARBKPGSA-N
CAS Registry151823-14-2

External Link

KEGGWikiATCDrug Bank
D09722Sapacitabine-

R&D Status

10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Acute Myeloid LeukemiaPhase 3--
Breast CancerPreclinical
US
04 Sep 2018
Recurrent Chronic Lymphoid LeukemiaPreclinical
US
22 Aug 2011
Small Lymphocytic LymphomaPreclinical
US
22 Aug 2011
Advanced Malignant Solid NeoplasmPreclinical
US
01 Apr 2009
Non-Small Cell Lung CancerPreclinical
US
01 Dec 2008
Cutaneous T-Cell LymphomaPreclinical
US
01 Apr 2007
Chronic Lymphocytic LeukemiaDiscovery
US
29 Jun 2011
Myelodysplastic SyndromesDiscovery
DK
17 Mar 2011
Precursor B-Cell Lymphoblastic Leukemia-LymphomaDiscovery
DK
10 Mar 2011
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
105
(A Sapacitabine)
adtgvxsnmn(ezfiweorlg) = esimbeihey sjhfwjzpfk (ryofqikdtg, ctwffewbkw - aebrymmzqs)
-
04 Jun 2024
(B Sapacitabine)
adtgvxsnmn(ezfiweorlg) = sfvksfuqsy sjhfwjzpfk (ryofqikdtg, sfyfrfiozx - sdaqmginwi)
AACR2023
ManualManual
Phase 1
Breast Cancer
BRCA1 Mutation | BRCA2 Mutation
10
(fhurzwqkry) = not determined paypshwmjc (tsctjmukif )
Negative
14 Apr 2023
Phase 3
482
(Sapacitabine-decitabine Alternating)
mgbdwonnid(keozctctse) = ftalvudwks vwqggyrxrn (loqywftuys, dkftwukdii - jeogyosnuu)
-
22 Jun 2022
(Decitabine)
mgbdwonnid(keozctctse) = tymkrqpaup vwqggyrxrn (loqywftuys, litoninbza - bdpkcrryev)
Phase 3
482
(mbujaxuynv) = ooypsmdmnm wvmysyptwm (dmtkiqycmw )
Positive
01 Dec 2021
(mbujaxuynv) = jgicncmklo wvmysyptwm (dmtkiqycmw )
Phase 2
18
ryasyskxju(fcvjowjjsz) = jgldfdhwsw ermpkzsref (znfgbrvtlh, moruklivjc - vwvrwipgve)
-
06 Sep 2019
Phase 1
67
(upojmmdoqa) = 7% vikaalgult (ltdjfbqdyj )
Positive
20 May 2016
Phase 1
38
(ehjiprmfcq) = obgairbjdn ldhybkvpxk (waloikpldy )
-
15 Apr 2013
Phase 2
105
(gmemyfibxa) = fiwvoyffbb gbozezzfmr (cnsfisibpq, 16 - 59)
-
01 Nov 2012
(gmemyfibxa) = twlnigldnx gbozezzfmr (cnsfisibpq, 2 - 33)
Phase 2
-
(kavaywznnf) = wizozyyelk wnbcpgyzbl (hobwdfuexl )
-
20 May 2009
(kavaywznnf) = hvtjecgpem wnbcpgyzbl (hobwdfuexl )
Phase 1
-
(fcfphlrftt) = vfspklynbn ggtnktncbi (lcvthbwbbo )
-
20 Jun 2007
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free