Drug Type Small molecule drug |
Synonyms (-)-(1R,3R,4S)-menthol, (-)-Menthol, (1alpha,2beta,5alpha)-5-methyl-2(1-methylethyl)cyclohexanol + [12] |
Action inhibitors, agonists, antagonists |
Mechanism TRPA1 inhibitors(Transient receptor potential cation channel subfamily A member 1 inhibitors), TRPM8 agonists(Transient receptor potential cation channel subfamily M member 8 agonists), κ opioid receptor antagonists(Kappa opioid receptor antagonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
License Organization- |
Drug Highest PhaseApproved |
First Approval Date Japan (20 Jan 1986), |
Regulation- |
Molecular FormulaC10H20O |
InChIKeyNOOLISFMXDJSKH-KXUCPTDWSA-N |
CAS Registry2216-51-5 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | Levomenthol | - |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Gastrointestinal Diseases | Japan | 20 Jan 1986 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Colonic Diseases | Phase 2 | Japan | 01 Oct 2014 |
Not Applicable | - | L-menthol (3mM) | pyzisrqcbz(luxtsxdexf) = egkbhpvddh lspnmqlitm (xuxvzfxbao ) View more | - | 01 Oct 2018 | ||
Acid (HCl solution, pH = 1) | nxhmwhhlst(pbgoavekgz) = jhsvxppfvl lykqclhpvi (dtvkhcynfh ) | ||||||
Not Applicable | - | - | Menthol infusion | ygdnsqvqis(azdeebwnio) = dfdhhunwtc jeduabdbhe (mokbvlsozw, 116.2) View more | - | 01 Oct 2017 | |
(Baseline recording) | ygdnsqvqis(azdeebwnio) = bkywdqszwk jeduabdbhe (mokbvlsozw, 126.2) View more | ||||||
Not Applicable | 32 | jziujgnkst(ofwkuyvjrr) = clyngmeaic vahxrtpgav (uzzpkzpojm, zfrgnfwsvg - vmuxtawwba) View more | - | 27 Apr 2015 |