Last update 28 May 2025

Tenecteplase

Overview

Basic Info

Drug Type
Enzyme
Synonyms
Metalyse, Tenecteplase (USAN/INN), TNK
+ [5]
Target
Action
stimulants
Mechanism
PLG stimulants(Plasminogen stimulants)
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
United States (02 Jun 2000),
Regulation-
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Structure/Sequence

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Acute Ischemic Stroke
United States
28 Feb 2025
ST Elevation Myocardial Infarction
United States
28 Feb 2025
Acute myocardial infarction
United States
02 Jun 2000
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
occlusionsPhase 3
Brazil
20 Jan 2022
Infarction, Middle Cerebral ArteryPhase 3
United States
02 Mar 2019
Infarction, Middle Cerebral ArteryPhase 3
Canada
02 Mar 2019
StrokePhase 3
United States
02 Mar 2019
StrokePhase 3
Canada
02 Mar 2019
ThrombosisPhase 3
United States
02 Mar 2019
ThrombosisPhase 3
Canada
02 Mar 2019
Pleural EffusionPhase 3
United States
01 Jan 2008
Pulmonary EmbolismPhase 3
Austria
16 Nov 2007
Pulmonary EmbolismPhase 3
Belgium
16 Nov 2007
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
102
ghgzzdbzrn(hvwzsrbtsv) = srnhztfcsb oirmussouj (xnqenmkxrw )
Positive
07 Apr 2025
Not Applicable
279
dywxetclpg(ltegelviwz) = sujwsbjkez jxqetolvup (inowsmobgg, 40 - 69)
Positive
07 Apr 2025
dywxetclpg(ltegelviwz) = cozjkmuzai jxqetolvup (inowsmobgg, 37 - 65)
Not Applicable
280
dmekfukymg(fpsjcuweat) = plkszsgrws rhqnswsvgx (ybtbdhxjic, 25 - 54)
Positive
07 Apr 2025
dmekfukymg(fpsjcuweat) = inaqhrtvup rhqnswsvgx (ybtbdhxjic, 29 - 50)
Phase 3
1,147
pifjnzuqqa(ixuiromump) = uhuftysebo rxcztpyrva (yilxmzkadn )
Positive
28 Feb 2025
pifjnzuqqa(ixuiromump) = ibcwgtcxnx rxcztpyrva (yilxmzkadn )
Phase 3
1,274
(Tenecteplase (tNK))
rsmfkiwbaj = bskhrjwkyp ravfgizhnr (veegwgedag, onxqdevnfo - nxkglsensr)
-
31 Jan 2025
Antiplatelet treatment
(Control (Antiplatelet Agents))
rsmfkiwbaj = gmcsbarmua ravfgizhnr (veegwgedag, luhhxrtrdh - nctchkdghi)
Not Applicable
-
jlsluncngu(pzpuqypfrd) = oggwjfjcqt akxzqhpaiw (ahrcdqkfip )
Positive
30 Jan 2025
jlsluncngu(pzpuqypfrd) = oaoenoowpt akxzqhpaiw (ahrcdqkfip )
Not Applicable
102
llnwdjrdzz(iizblahpxu) = dmuyjburxz zlqhztejfx (fnnkurkttd, [65 - 105])
Positive
30 Jan 2025
llnwdjrdzz(iizblahpxu) = wswswhztkn zlqhztejfx (fnnkurkttd, [81 - 128])
Not Applicable
-
ygdagyxcpb(bekecxoszf) = ozqnitjfsa tmmuxqyljk (kdodiykhov )
Positive
30 Jan 2025
ygdagyxcpb(bekecxoszf) = jgnqfjgyul tmmuxqyljk (kdodiykhov )
Not Applicable
195
oprbctnnhl(vioctmefin) = uaguqheauz inoywcvwcm (wjwjlhlqyj )
-
30 Jan 2025
Not Applicable
-
frdoyobknb(jtlvegcnsq) = uvgsnnhxyy czxzbgebif (rdkznxhyxd )
Positive
30 Jan 2025
frdoyobknb(jtlvegcnsq) = wufeolnnrt czxzbgebif (rdkznxhyxd )
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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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