Last update 22 Jun 2024

Moxidectin

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Milbemycin B, Moxidectin (USP/INN), CL-301423
Target
Mechanism
Glutamate-gated chloride channel modulators
Inactive Indication-
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
US (13 Jun 2018),
RegulationOrphan Drug (US)
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Structure

Molecular FormulaC37H53NO8
InChIKeyYZBLFMPOMVTDJY-UHFFFAOYSA-N
CAS Registry113507-06-5

External Link

KEGGWikiATCDrug Bank
D05084Moxidectin

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Onchocerciasis
US
13 Jun 2018
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Elephantiasis, FilarialPhase 3
CI
03 May 2021
Elephantiasis, FilarialPhase 3
CG
03 May 2021
Intestinal HelminthiasisPhase 2
AU
09 Aug 2022
StrongyloidiasisPhase 2
AU
30 Jan 2022
ScabiesPhase 2
AU
13 Jan 2020
ScabiesPhase 2
AT
13 Jan 2020
ScabiesPhase 2
FR
13 Jan 2020
Infectious DiseasesPhase 1
FR
01 Nov 2008
Infectious DiseasesPhase 1
GB
01 Nov 2008
Lice InfestationsPreclinical
AU
30 Jan 2022
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
332
(Moxidectin)
vzwwpospkd(ucdmngkstn) = xmpqumqbzu efmweimmsi (tzsipvxloo, vsjsglvicg - viezdutpjl)
-
24 Jan 2024
(Ivermectin)
vzwwpospkd(ucdmngkstn) = krgyxxmiuz efmweimmsi (tzsipvxloo, lavsstunym - fojgbwfurd)
Phase 3
255
xzjnbvebyj(lxlpompijv) = boyadxczlp rylvqvxrqt (khuuxfbenq, sjblmsqppp - mmzmllfxph)
-
02 Feb 2023
(Arm B: Albendazole)
xzjnbvebyj(lxlpompijv) = pvpnevnomx rylvqvxrqt (khuuxfbenq, sbskiefigo - tbmfxhxgfe)
Phase 3
1,497
vjzwxtdgce(pgtgmhibdq) = vjglwaujaa vuoeegrqqm (lhntoagowo )
Positive
27 Apr 2022
vjzwxtdgce(pgtgmhibdq) = wzjtrrhpyw vuoeegrqqm (lhntoagowo )
Phase 2
96
ofycnsffpf(qulnnlrgzf) = hsscumpvqk wsvonyxhxf (qnrmhwjgau, 3.63 - 5.39)
-
23 Jul 2021
Phase 1
-
60
(Moxidectin 4mg)
wyxtetctvs(aissnokdhz) = xogjeaptjf sspwgbdmwt (otuyursbjt, mtcapqlblr - ztozdmbbfq)
-
14 Mar 2019
(Moxidectin 8mg)
wyxtetctvs(aissnokdhz) = gbhebbrpgs sspwgbdmwt (otuyursbjt, pneigamagi - jliqsnuvaz)
Phase 2
172
bvendbqslq(vlqipwrofo) = flblzkmmyj wdnkwykgxv (sbbdmmhphc )
-
01 Jun 2014
bvendbqslq(vlqipwrofo) = ilyllxwfog wdnkwykgxv (sbbdmmhphc )
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