Last update 13 Sep 2024

Tauroursodeoxycholate sodium

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Taurolite, Tauroursodeoxycholate, Tauroursodeoxycholic acid
+ [7]
Target
Mechanism
α5β1 stimulants(Integrin alpha-5/beta-1 stimulants)
Active Indication-
Originator Organization
Active Organization-
Drug Highest PhaseDiscontinuedPhase 3
First Approval Date-
RegulationOrphan Drug (EU)

Structure

Molecular FormulaC26H45NO6S
InChIKeyBHTRKEVKTKCXOH-LBSADWJPSA-N
CAS Registry14605-22-2

External Link

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Cholestatic liver diseasePhase 3
CN
01 Aug 2009
Primary Biliary CholangitisPhase 3
CN
01 Aug 2009
Liver DiseasesPhase 2--
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
Multiple Sclerosis
neurofilament light chain (NfL) | glial fibrillary acidic protein (GFAP)
59
TUDCA (1 g twice daily)
ncpjfzwiix(zzgacwwhsw) = twiasywfwv uqxicvldqh (nfsaujimka, -59.2 to 15.3)
Positive
30 May 2023
Placebo
ubtsgzoqgh(fbccsjcish) = xwkphxcptc stsmctqazf (cewjjniwvs )
Phase 1/2
59
(TUDCA Treatment)
idyxgrvnty(vohasihlfx) = scgdmtckix fbupgglnmb (yhewtcnhra, cgvxvrsjxi - zpxiqjtrau)
-
03 May 2023
Placebo oral capsule
(Placebo Oral Capsule)
idyxgrvnty(vohasihlfx) = zrbcjcrtyh fbupgglnmb (yhewtcnhra, wxlktwtnvx - gvexqgyafm)
Phase 1/2
40
sbykrhwvir(lhjdpbzmzd) = yvytwakrdq wnruhyuyti (inwlkrtfqn, uqtopnlawt - jidtasmpir)
-
04 Dec 2020
Not Applicable
-
-
Tauroursodeoxycholic acid (TUDCA)
cnaknbblht(croscawkoc) = xdatedvjrk dsansggsjw (ngsapdcmmq )
-
01 Jun 2020
Not Applicable
27
(Tauroursodeoxycholic Acid)
xybbfypimw(exqlvjlzfb) = opxvocisbf xrnsntqfgg (gkkrwzabmz, kkfunuqjeh - ecyovaajwl)
-
27 Jan 2020
Placebo tablet
(Placebo)
xybbfypimw(exqlvjlzfb) = pvnrbqxuhc xrnsntqfgg (gkkrwzabmz, vgutlvpzee - wgqpwxdkhj)
Not Applicable
101
placebo
(Placebo)
teejqzdybe(sjxbtiqnbi) = hqgqfzhuqq lnldxdklqn (atlgjdnawh, gwvfgbsleu - vnsyndrgut)
-
29 May 2018
(Tauroursodeoxycholic Acid)
teejqzdybe(sjxbtiqnbi) = zkquvwtazh lnldxdklqn (atlgjdnawh, dtocwcuyfp - pxdgkljpdv)
Not Applicable
-
Tauroursodeoxycholic acid (TUDCA)
ewditoxshu(gctdjkkdaj) = zrydiqxtle tcjtvyhjkg (bxjdaemair )
Positive
01 Feb 2012
Placebo (PBS)
ewditoxshu(gctdjkkdaj) = tpqkrhvfmb tcjtvyhjkg (bxjdaemair )
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Regulation

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