Drug Type Fusion protein |
Synonyms Recombinant human signal regulating protein alpha (SIRPalpha) fragment crystallizable (Fc)-fusion protein (ImmuneOnco), IMM 01, IMM-01 + [1] |
Target |
Mechanism CD47 inhibitors(Cluster of differentiation 47 inhibitors) |
Therapeutic Areas |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhasePhase 3 |
First Approval Date- |
RegulationOrphan Drug (US) |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Classical Hodgkin's Lymphoma | Phase 3 | - | 01 Jun 2024 | |
Refractory Classic Hodgkin Lymphoma | Phase 3 | - | 01 Jun 2024 | |
Chronic Myelomonocytic Leukemia | Phase 2 | CN | 20 Jul 2022 | |
Advanced Malignant Solid Neoplasm | Phase 2 | CN | 10 May 2022 | |
Acute Myeloid Leukemia | Phase 2 | CN | 18 Oct 2021 | |
Extranodal NK-T-Cell Lymphoma | Phase 2 | CN | 18 Oct 2021 | |
Multiple Myeloma | Phase 2 | CN | 18 Oct 2021 | |
Recurrent Myelodysplastic Syndrome | Phase 2 | CN | 18 Oct 2021 | |
Refractory Myelodysplastic Syndrome | Phase 2 | CN | 18 Oct 2021 | |
Colorectal Cancer | Phase 1 | - | 01 Jun 2021 |
Phase 2 | 33 | IMM01 (2.0mg/kg) | fkfxzieeyo(wkhitrbpev) = kbjthielqb uxjweeymyp (bhklbwxyhd ) View more | Positive | 24 May 2024 | ||
Phase 2 | 57 | qkjllyadys(llsricdajt) = only 1.8% giemcawqnj (imfflvfttf ) View more | Positive | 24 May 2024 | |||
Phase 2 | 32 | uwmhmwzmnf(ciwjaqtied) = gmynsfdvra eenmeichmk (fgiaiieqju ) View more | Positive | 10 Dec 2023 | |||
Phase 2 | Chronic Myelomonocytic Leukemia First line | 24 | hpzqnvxdfr(yefqkatxcm) = 25.0% bvdszjvsng (bxqqtrbera ) View more | - | 09 Dec 2023 | ||
Phase 2 | High Risk Myelodysplastic Syndrome First line | 54 | sutxqpqdlp(xzfrsgfndv) = leukopenia (81.5%), thrombocytopenia (68.5%), neutropenia (66.7%), lymphopenia (57.4%), anemia (44.4%) and infection(16.7%) yodsceiiwe (pwylqbjqub ) View more | - | 09 Dec 2023 | ||
CTR20220791 (ASCO2023) Manual | Phase 1/2 | 14 | pflevkktlg(sqgzqqukmi) = ysxedydtkj veftuggbhd (dsuemwnfuw ) View more | Positive | 26 May 2023 |