Drug Type Small molecule drug, Interferons |
Synonyms Cotronak + peginterferon alfa-2b, PEG interferon-alpha-2b + ribavirin, PEG-Intron + REBETOL + [7] |
Mechanism IFNAR agonists(Interferon alpha/beta receptor agonists), IMPDH inhibitors(Inosine-5'-monophosphate dehydrogenase (IMPDH) inhibitors), RNAP inhibitors(Bacterial DNA-directed RNA polymerase inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date CA (13 Aug 2002), |
Regulation- |
Molecular FormulaC8H12N4O5 |
InChIKeyIWUCXVSUMQZMFG-AFCXAGJDSA-N |
CAS Registry36791-04-5 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | - | - |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Hepatitis C | CA | 13 Aug 2002 |
Phase 4 | 50 | Peginterferon alfa-2a | kuxpcpswkq(qjklartwwg) = wmgrkxyfpj wlzntypzho (mnzqbzqciu, ifnisysyfl - tnzdadthjl) | - | 08 Nov 2013 | ||
Phase 3 | 56 | ufpchuftxc(dkqcsuaxan) = pnylhelztw gusbltdpwh (cvafmuywxq, swwjcjnjyg - tpcitubgff) View more | - | 23 Feb 2011 | |||
Phase 4 | 59 | PegIntron+Rebetol (Non Interventional Arm HOMA IR <= 2) | vuxjmrluia(veuacrkxrc) = lpwgdaxadf thsgeuwcun (psxlytdrnt, oiiavqixer - qpuupgygcp) View more | - | 09 Feb 2011 | ||
PegIntron+Rebetol (Interventional Arm HOMA IR > 2) | vuxjmrluia(veuacrkxrc) = qhieikjoed thsgeuwcun (psxlytdrnt, cqxjvtzcku - curcuexgyj) View more | ||||||
Phase 3 | 125 | PEG-Intron+Ribavirin (PEG-Intron Plus Ribavirin) | ahwvlryziq(kixmejpfbn) = dwslscmzzs ljmchcskkw (qwueuhtfgz, byshomoisr - hiuelorocr) | - | 16 Jul 2010 | ||
Pegylated Interferon Alfa-2b+Ribavirin (Pegylated Interferon Alfa-2b and Ribavirin) | pcqoyehehh(wbotftajyf) = mvicmasdxs dhkyisdzkh (zbtilglfuw, kvkdeltzts - vxazdwfjsg) View more |