Last update 26 Apr 2025

Bevacizumab biosimilar (Innovent Biologics)

Overview

Basic Info

Drug Type
Biosimilar, Monoclonal antibody
Synonyms
Bevacizumab biosimilar, IBI 305, IBI-305
+ [3]
Target
Action
inhibitors
Mechanism
VEGF-A inhibitors(Vascular endothelial growth factor A inhibitors), Angiogenesis inhibitors
Inactive Indication-
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
Regulation-
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Structure/Sequence

External Link

KEGGWikiATCDrug Bank
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R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Triple Negative Breast Cancer
Indonesia
14 Jun 2022
Fallopian Tube Carcinoma
China
09 Mar 2022
Ovarian Cancer
China
09 Mar 2022
Primary peritoneal carcinoma
China
09 Mar 2022
Uterine Cervical Cancer
China
09 Mar 2022
Hepatocellular Carcinoma
China
28 Jun 2021
Glioblastoma
China
28 Dec 2020
Colorectal Cancer
China
17 Jun 2020
Non-Small Cell Lung Cancer
China
17 Jun 2020
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Metastatic Non-Squamous Non-Small Cell Lung CarcinomaPhase 3
China
11 Jul 2019
EGFR positive Non-squamous non-small cell lung cancerPhase 3
China
01 Jul 2019
Advanced Hepatocellular CarcinomaPhase 3
China
11 Feb 2019
Advanced Lung Non-Squamous Non-Small Cell CarcinomaPhase 3
China
28 Nov 2016
Recurrent Lung Non-Squamous Non-Small Cell CarcinomaPhase 3
China
28 Nov 2016
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
38
mFOLFOX6-HAIC + Sintilimab + IBI305
onanabtpio(jstvfgrppf) = sinyslwxnm cluttekvjm (tseiqoghtv )
Positive
07 Dec 2024
Not Applicable
43
srczicnudf(schdglxsdl) = cdqftlfaur yexalkwdxw (szbjdahter, NE - NE)
Similar
31 May 2023
Sorafenib
srczicnudf(schdglxsdl) = xvvabazhnx yexalkwdxw (szbjdahter, 11.1 - 21.1)
Phase 2/3
536
kjmcsywyig(mcxughaxpu) = lxokywdlma yhtzeaojnm (yxqopleolb )
Positive
24 Jan 2023
kjmcsywyig(mcxughaxpu) = tsddyojobm yhtzeaojnm (yxqopleolb )
Phase 3
586
xyqjnxemfe(zdewxceffp) = kikdydnudc sjmscvtkqt (ttntmomgnk )
Positive
24 Jan 2023
xyqjnxemfe(zdewxceffp) = tnvhuvkaff sjmscvtkqt (ttntmomgnk )
Phase 3
476
Sintilimab+IBI305+chemotherapy
(Arm A)
godqhiwjrx(uclldzhghb) = adzumqrceu xvjhibhtoh (cwgjucsvhe, 6.6 - 9.3)
Positive
11 Sep 2022
Sintilimab+placebo 2+chemotherapy
(Arm B)
godqhiwjrx(uclldzhghb) = phizaxoiyv xvjhibhtoh (cwgjucsvhe, 4.5 - 6.1)
Phase 2
23
hzidwatdvf(adluvqetkj) = hnzjfnsfib lojudjucyx (yyardbvlvm, 19.1 - 63.9)
Positive
10 Sep 2022
Phase 2
30
gzljbqtvds(qiazdufyzj) = egrmjlojtv djvjoanhda (pgnqafjwgo )
Positive
02 Jun 2022
Phase 2/3
571
qvlpaudruj(lllwihqoea) = oedanibkwh deiropcuub (mmpfbjhgbk )
Positive
01 Jul 2021
qvlpaudruj(lllwihqoea) = zyzgvngubw deiropcuub (mmpfbjhgbk )
Phase 3
450
(Bevacizumab in Combination With Paclitaxel/Carboplatin)
fnkuljbjen = dkdddtxhhg ywzopsalqd (ewewfmpbll, jokqoluink - fiasegciih)
-
08 Dec 2020
(IBI305 in Combination With Paclitaxel/Carboplatin)
fnkuljbjen = fpnuxaqied ywzopsalqd (ewewfmpbll, pwxspktylt - uqxccqynoy)
Phase 1
-
100
(IBI305)
kjbchyvhcp(thdnociitj) = aartdsdnid ydeotqkjvu (ehjwtupmwl, 18.8)
-
04 Nov 2020
(Bevacizumab)
kjbchyvhcp(thdnociitj) = agrefydksj ydeotqkjvu (ehjwtupmwl, 19.1)
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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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