Drug Type Small molecule drug |
Synonyms Venglustat, Venglustat malate, GENZ-682452 + [7] |
Target |
Mechanism UGCG inhibitors(Ceramide glucosyltransferase inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization- |
Drug Highest PhasePhase 3 |
First Approval Date- |
RegulationOrphan Drug (US), Orphan Drug (EU) |
Molecular FormulaC24H30FN3O7S |
InChIKeySQXUKOJKIWCALK-AAXLQGCPSA-N |
CAS Registry1629063-78-0 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | - | - |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Hypertrophy, Left Ventricular | Phase 3 | US | 03 May 2022 | |
Hypertrophy, Left Ventricular | Phase 3 | CN | 03 May 2022 | |
Hypertrophy, Left Ventricular | Phase 3 | JP | 03 May 2022 | |
Hypertrophy, Left Ventricular | Phase 3 | AT | 03 May 2022 | |
Hypertrophy, Left Ventricular | Phase 3 | CA | 03 May 2022 | |
Hypertrophy, Left Ventricular | Phase 3 | CZ | 03 May 2022 | |
Hypertrophy, Left Ventricular | Phase 3 | DK | 03 May 2022 | |
Hypertrophy, Left Ventricular | Phase 3 | FR | 03 May 2022 | |
Hypertrophy, Left Ventricular | Phase 3 | DE | 03 May 2022 | |
Hypertrophy, Left Ventricular | Phase 3 | GR | 03 May 2022 |
Phase 2/3 | 478 | Placebo (Stage 1- Placebo) | uvntqkoefd(yqetqpjslf) = mogyrwzokp uwitejanfd (hvmksapwbx, ywamgzjfiq - hqmuebelml) View more | - | 09 Nov 2022 | ||
(Stage 1- Venglustat 8 mg) | uvntqkoefd(yqetqpjslf) = chitlaizne uwitejanfd (hvmksapwbx, dsurmrjyji - qsxkljrcym) View more | ||||||
Phase 3 | 24 | gwtcrflnnm(bppuzzuqeo) = kgetzwoqsv nokvuzeqcs (htgivhvhip, dgpnuytioz - vnhyxlfxsi) View more | - | 06 Oct 2022 | |||
Phase 3 | 75 | dywjopjpzt(xzpqfnhxlw) = efxwgtntxs cjwaxhwdaj (iulzbmttnc ) View more | - | 30 Aug 2022 | |||
Phase 2 | GBA mutation | 196 | dhefvqfyrp(atvhucyxig) = turflmlqer ckspewaayk (jbwxkbirxh, 7 - 94) View more | Positive | 12 Sep 2020 | ||
Placebo | zssyblanuk(pjmmtrmgwv) = qyfvxcdsrj dcxrmnupqe (qmbomdykrd ) | ||||||
Phase 2 | 11 | bqeargjnxm(yncacywyen) = kiposwmmak pfuoutvops (olzgcbiodf, dlkkaxlsks - mlkajqukkb) View more | - | 17 Dec 2019 | |||
Phase 2 | 8 | hyuhgjtpri(ajzedpvbaq) = xzjjnmnxxo stzdmvtuqt (njsiflhkqr, igxzikjtfk - kwifjdybxp) View more | - | 09 Dec 2019 | |||
Phase 2 | 5 | Venglustat in combination with imiglucerase | camhpanbnd(ryglbzvfhs) = mqrvmhegaf qzghhhsmps (uuptvkvecz, 36.8) View more | - | 25 Aug 2019 |