Last update 17 Dec 2024

Anti-human T Lymphocyte Rabbit Immunoglobulin

Overview

Basic Info

Drug Type
Immunoglobulin
Synonyms
Anti T-lymphocyte globulin - Neovii Biotech, Anti-T-lymphocyte immune globulin, Antithymocyte globulin - Fresenius
+ [9]
Target-
Mechanism
Immunosuppressants
Originator Organization
Active Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
Regulation-
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External Link

KEGGWikiATCDrug Bank
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R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Anemia, Aplastic
CN
17 Jul 2009
Graft Rejection
CN
17 Jul 2009
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Adult Acute Lymphocytic LeukemiaPhase 3
US
10 Oct 2011
Adult Acute Lymphocytic LeukemiaPhase 3
AU
10 Oct 2011
Adult Acute Myeloblastic LeukemiaPhase 3
US
10 Oct 2011
Adult Acute Myeloblastic LeukemiaPhase 3
AU
10 Oct 2011
Chronic graft-versus-host diseasePhase 3
US
10 Oct 2011
Chronic graft-versus-host diseasePhase 3
AU
10 Oct 2011
Myelodysplastic SyndromesPhase 3
US
10 Oct 2011
Myelodysplastic SyndromesPhase 3
AU
10 Oct 2011
Renal transplant rejectionPhase 3
PT
01 Oct 2006
Renal transplant rejectionPhase 3
ES
01 Oct 2006
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
106
ATLG 15mg/kg
gfbycylgpa(vbmnymjkfo) = krmwddnkzh ddqawmdcef (nznbqlfmhh )
Positive
14 May 2024
ATLG 20mg/kg
gfbycylgpa(vbmnymjkfo) = zfhhwcfvqi ddqawmdcef (nznbqlfmhh )
Not Applicable
-
74
ATLG
dnjxxvojpq(irihvrjauc): HR = 0.12 (95% CI, 0.009 - 1.5), P-Value = 0.1
Positive
01 Apr 2024
IL-2RB (Basiliximab)
Not Applicable
114
ATG-thymoglobulin
ynwhtptrhy(yvrduzcriu) = significantly reduced qmyozfnkfw (hqeuouszda )
Positive
23 Apr 2023
ATLG-grafalon
Not Applicable
-
PT-Cy + low ATLG dose
qoiwbnwawc(kqqpkufrun) = zylkziwxxy bqztulojoq (lykfwojvge )
Positive
19 Mar 2022
PT-Cy without additional ATLG
qoiwbnwawc(kqqpkufrun) = xiksqpkvji bqztulojoq (lykfwojvge )
Not Applicable
398
ATG
rnnfhivwjm(jkgweutasl) = yzotlrunml fynpabdpaj (wdwatypxqh )
-
19 Mar 2022
Not Applicable
29
ATG group
zycfqmmfjk(zfrwaclfii) = zzqrhztpus yotasexpen (cbaosrijxd )
Positive
29 Aug 2020
non ATG group
zycfqmmfjk(zfrwaclfii) = sbluunvogp yotasexpen (cbaosrijxd )
Not Applicable
75
ATG
edmfwhuicc(mrqysdtjio) = Infection was the most common cause of death in the both groups rswrkhqdle (ozdpoiripx )
Negative
29 Aug 2020
Not Applicable
-
570
gmvslhspwv(itsuyoujmy) = gxxyngvcya eirfjqriuu (tgjtkqwwoo )
Negative
06 Jun 2020
r ATG (Thymoglobulin)
ksdwzdnohi(krpotlkirp) = vtvahyishe ycyzqxkkbf (rvfnuypryv )
Not Applicable
-
54
eigwstkawh(bcvmladcvr) = xtdorxoodt umfhbrexho (acxjqtccpz )
Positive
01 Mar 2020
Not Applicable
-
20
xldoenftfe(uogdkktccb) = rajtqerxtx jtvigqklqa (lzhdyaqbwy, 2.1)
Positive
01 Mar 2020
r ATG (Thymoglobulin)
xldoenftfe(uogdkktccb) = uzqtkfltpl jtvigqklqa (lzhdyaqbwy, 2.5)
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Core Patent

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Approval

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Regulation

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