Last update 11 Jul 2024

Brilaroxazine

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
6-(4-(4-(2,3-Dichlorophenyl)-piperazin-1-yl)-butoxy)-2H-benzo(b)(1,4)oxazin-3(4H)-one, Brilaroxazine Hydrochloride
+ [3]
Mechanism
5-HT1A receptor partial agonists(Serotonin 1a (5-HT1a) receptor partial agonists), 5-HT2A receptor partial agonists(Serotonin 2a (5-HT2a) receptor partial agonists), 5-HT6 receptor antagonists(Serotonin 6 (5-HT6) receptor antagonists)
+ [4]
Originator Organization
Inactive Organization-
Drug Highest PhasePhase 3
First Approval Date-
RegulationOrphan Drug (US)

Structure

Molecular FormulaC22H25Cl2N3O3
InChIKeyPMKMNTBZJOXTJW-UHFFFAOYSA-N
CAS Registry1239729-06-6
View All Structures (2)

External Link

KEGGWikiATCDrug Bank
-Brilaroxazine-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
SchizophreniaPhase 3
US
24 Jan 2022
Acute schizophreniaDiscovery
MY
01 Dec 2011
Acute schizophreniaDiscovery
PH
01 Dec 2011
Acute schizophreniaDiscovery
MD
01 Dec 2011
Acute schizophreniaDiscovery
IN
01 Dec 2011
Schizoaffective disorderDiscovery
US
01 Dec 2011
Schizoaffective disorderDiscovery
IN
01 Dec 2011
Schizoaffective disorderDiscovery
PH
01 Dec 2011
Schizoaffective disorderDiscovery
MY
01 Dec 2011
Schizoaffective disorderDiscovery
MD
01 Dec 2011
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
-
veaqboxfeq(lfivspktex) = qsugxnavmy papxhkmuzk (qbdbivnxiu )
Met
Positive
30 Oct 2023
Placebo
veaqboxfeq(lfivspktex) = euwgbyckpe papxhkmuzk (qbdbivnxiu )
Met
Phase 2
234
placebo
povnneuvyj(irofelohvj) = bkmzkzfays kjflummwxe (yrlyjktjyd, dhtmzvzxjy - ougvmibhki)
-
26 Jan 2015
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Regulation

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