Last update 21 Jun 2024

Brilaroxazine

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
6-(4-(4-(2,3-Dichlorophenyl)-piperazin-1-yl)-butoxy)-2H-benzo(b)(1,4)oxazin-3(4H)-one, Brilaroxazine Hydrochloride, RP 5000
+ [3]
Mechanism
5-HT1A receptor partial agonists(Serotonin 1a (5-HT1a) receptor partial agonists), 5-HT2A receptor partial agonists(Serotonin 2a (5-HT2a) receptor partial agonists), 5-HT6 receptor antagonists(Serotonin 6 (5-HT6) receptor antagonists)
Originator Organization
Inactive Organization-
Drug Highest PhasePhase 3
First Approval Date-
RegulationOrphan Drug (US)

Structure

Molecular FormulaC22H25Cl2N3O3
InChIKeyPMKMNTBZJOXTJW-UHFFFAOYSA-N
CAS Registry1239729-06-6

External Link

KEGGWikiATCDrug Bank
-Brilaroxazine-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
SchizophreniaPhase 3
US
24 Jan 2022
Acute schizophreniaPhase 2
US
01 Dec 2011
Acute schizophreniaPhase 2
IN
01 Dec 2011
Acute schizophreniaPhase 2
MY
01 Dec 2011
Acute schizophreniaPhase 2
MD
01 Dec 2011
Acute schizophreniaPhase 2
PH
01 Dec 2011
Schizoaffective disorderPhase 2
US
01 Dec 2011
Schizoaffective disorderPhase 2
IN
01 Dec 2011
Schizoaffective disorderPhase 2
MY
01 Dec 2011
Schizoaffective disorderPhase 2
MD
01 Dec 2011
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
-
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Met
Positive
30 Oct 2023
Placebo
bljvcrcahg(eaasdmpwyf) = tmsquvllxr qmaijilsbq (iqgirqliav )
Met
Phase 2
234
placebo
yzdfsapras(nkhigqrtaa) = ctakrgxidx jvmsldnkky (djphbzckkr, upfklmwtos - hbjvkrntna)
-
26 Jan 2015
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Regulation

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