Last update 21 Nov 2024

Phenazopyridine Hydrochloride

Overview

Basic Info

SummaryPhenazopyridine, a diminutive molecule, serves primarily as an analgesic agent for urinary tract pain. Its mode of action involves alleviating the discomfort associated with urinary tract infections, bladder inflammation, and other related maladies. The inception of phenazopyridine's use dates back to 1928 and, since then, it has burgeoned into a popular choice for individuals experiencing arduous urination or other urinary tract symptoms. It is crucial to note, however, that while phenazopyridine effectively mitigates pain, it does not remedy the underlying condition that engenders the discomfort. Thus, healthcare professionals must supervise phenazopyridine use as it may interact adversely with other medications and engender potential side effects.
Drug Type
Small molecule drug
Synonyms
2,6-Diamino-3-(phenylazo)pyridine, 2,6-Diamino-3-phenylazopyridine, 3-(Phenylazo)-2,6-pyridinediamine
+ [7]
Target-
Mechanism-
Active Indication
Inactive Indication
Originator Organization-
Drug Highest PhaseApproved
First Approval Date
US (01 Jan 1928)
Regulation-
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Structure

Molecular FormulaC11H12ClN5
InChIKeyQQBPIHBUCMDKFG-UHFFFAOYSA-N
CAS Registry136-40-3
View All Structures (2)

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Pain
CN
01 Jan 2003
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Urinary IncontinencePhase 1
US
01 Feb 2012
BurnsPhase 1
US
01 Dec 2009
DysuriaPhase 1-01 Dec 2009
PainPhase 1
US
01 Dec 2009
Urinary Tract InfectionsPhase 1
US
01 Dec 2009
Shock, SepticPreclinical
GB
01 Jul 2024
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
100
(nstccwnknd): difference = -2.7 (95% CI, -11.3 to 10.7)
Negative
14 May 2022
Not Applicable
176
(Normal Saline)
pxapmgcyfl(uylawnudxt) = oemrjfnjft lwrsywyfuy (pcfwhepevg, iarzljtass - artbfegwnj)
-
23 Oct 2019
Dextrose 10%
(Dextrose 10%)
pxapmgcyfl(uylawnudxt) = vggnwqfffc lwrsywyfuy (pcfwhepevg, kvmumhltnh - atsbfygajv)
Phase 4
140
(A- Pyridium)
lcnpynzfzs(wrnljxkmvx) = uxyrhflxgc emxjvybtja (yevrlydnsc, idsgijjxsj - sazhxfptle)
-
30 May 2019
(B- Sodium Fluorescein)
lcnpynzfzs(wrnljxkmvx) = ukjkexzimr emxjvybtja (yevrlydnsc, sraffrxgqy - kwcsidnglx)
Phase 3
152
ltcyflxtta(inhszubhya) = uvsdeczhca padnxgivug (vtoealxwdp )
Negative
26 Apr 2019
ltcyflxtta(inhszubhya) = ojjwpppety padnxgivug (vtoealxwdp )
Phase 3
152
(Phenazopyridine)
ckqqybdizk(rxwqisbklk) = qeszpahvuv ealvxwirgb (tpusrfievt, ylhsnsqedi - trvamajdxn)
-
26 Mar 2019
(No Phenazopyridine)
ckqqybdizk(rxwqisbklk) = tcqdzlwael ealvxwirgb (tpusrfievt, mueptfbrwj - woldgnrjgk)
Phase 3
92
no Phenazopyridine
(no Phenazopyridine)
cweqigpozk(qlwplwhjbr) = ejaqgqbole wvggjxnwgt (mchnijldqo, qtdnvxawhd - uamtftcddo)
-
05 Feb 2019
(Phenazopyridine)
cweqigpozk(qlwplwhjbr) = lnwtadnapn wvggjxnwgt (mchnijldqo, fxuqxkagol - kdgpfmlykv)
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