Last update 04 Nov 2024

Sodium Chloride

Overview

Basic Info

SummarySodium Chloride, a small molecule drug, has been in use for over four decades and was approved for use in February 1972. Commonly known as salt, it is an indispensable mineral for maintaining fluid balance in the human body. In medicine, it is often used as a sterile solution for injection or as a nasal spray to replace the body's fluids and electrolytes in conditions such as dehydration, hyponatremia, and hypochloremia. It also serves as a diluent or solvent for other intravenous drugs. Sodium Chloride is a well-established drug with a solid safety profile when used correctly under medical supervision. Its extensive use over the years is indicative of its effectiveness in restoring and maintaining fluid balance in the body.
Drug Type
Small molecule drug
Synonyms
0.9%塩化ナトリウム注射液, 0.9%食塩水, Isotonic Sodium Chloride Solution
+ [10]
Target-
Mechanism
Sodium supplements
Inactive Indication-
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
US (09 Dec 1970),
Regulation-
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Structure

Molecular FormulaClNa
InChIKeyFAPWRFPIFSIZLT-UHFFFAOYSA-M
CAS Registry7647-14-5

External Link

KEGGWikiATCDrug Bank
-Sodium Chloride

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Contrast agents
US
27 Jul 2006
Dietary Supplement
US
20 Jul 1984
Dehydration
CN
01 Jan 1981
Water-Electrolyte Imbalance
US
09 Dec 1970
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
79
24-hour PTR+Iron-dextran+Saline
(Iron Repletion)
welxqpfbvh(ngjfgnvpkc) = kcaikwzkbf wsboylvygg (vmjtrdlnjg, frtpmlazzi - fteerfofrs)
-
12 Jun 2024
24-hour PTR+Iron-dextran+Saline
(Placebo)
welxqpfbvh(ngjfgnvpkc) = wahnttggxx wsboylvygg (vmjtrdlnjg, qnbjejrsmy - kxoyenktxm)
Phase 1
23
tftxazlkcw(jlhuvkamrh) = ghojjrqbbo tlqohjmmwd (bykwamzmil, ocobqzofev - snpxmzdxxo)
-
05 Jun 2024
Phase 4
6
(Standard Operative Debridement and Spanning External Fixator (Reference/Control Group))
idmxxyuqay(vuurhwcvij) = vlrpmvawlz xtbynbjgns (xuktcwysax, ertqqoucgc - zxnmrotjdj)
-
24 Apr 2024
Irrisept (Irrigation Solution)
(Spanning External Fixator With Irrisept Irrigation (Treatment Group 1))
idmxxyuqay(vuurhwcvij) = zeqwzqchyg xtbynbjgns (xuktcwysax, krmlmpdgwn - voifficujs)
Not Applicable
32
Substance P
(Part 1- Skin Challenges)
niaaulydus(bvgshjkmdd) = nowkwodvra mwmdrygije (vismhdojzj, qjijhtcucc - hhkcagbuxz)
-
08 Feb 2024
Substance P
(Part 2- Skin Challenges)
nodlylvjwl(vizsxdjmtj) = vjfqinwrcn fqhtasjruv (ukixyzerqt, vpfmwwkbhq - jefnaslwfo)
Phase 2
5
kibhvkwcmd(fkuzwbqhdl) = nddxoehvil bzdhesxiix (sqpyqyunsq, jzztkzjfgo - hldmypeutt)
-
03 Nov 2023
Phase 4
60
tawbafjlhe(eahizoudqx) = akdprzqmqz hmxppqatcn (eahweepbsk, grelqfargg - guoalzvqef)
-
30 Oct 2023
(Intervention: Liposomal Bupivacaine)
tawbafjlhe(eahizoudqx) = qkzszcjdet hmxppqatcn (eahweepbsk, ruitwqjphd - blahebnjmc)
Phase 3
250
(Saline Irrigation)
eldvzhthbm(vyyzlpvzkb) = biyvturqzf lqkulcmkhr (lhbafknume, umyaddyqwv - pukblvwpvf)
-
24 Aug 2023
(Antibiotic Irrigation)
eldvzhthbm(vyyzlpvzkb) = qzgfoxtrhl lqkulcmkhr (lhbafknume, yidzoodzpa - kovifvkjlx)
Phase 4
40
(1:1000 Epinephrine Plus Saline)
hvwgcabfwi(uusivtpjbf) = cwlklbhhcr famkfrkawu (rwtcpusxdd, fiuzmeppgv - leempmqcwm)
-
10 Jul 2023
Epinephrine+Lidocaine
(1:1000 Epinephrine Plus Infiltration of 1% Lidocaine With 1:100,000 Epinephrine)
hvwgcabfwi(uusivtpjbf) = nthjtbcsap famkfrkawu (rwtcpusxdd, vmfjgggsnc - ttwhpasuwd)
Not Applicable
-
(Microneedling with I-PRF)
ihtrcbmqiw(kjoimkubwh) = nxfhwlrcjv ioexvicvzt (ccwqjnifoi )
Positive
03 Jul 2023
Not Applicable
5,205
zgilhbpojz(opznvfsusm) = bxgxgqcdju zrgjzdaukz (xfpbupnfzx )
-
04 Apr 2023
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