Last update 21 Nov 2024

HER2 cancer vaccine(Pevion Biotech AG)

Overview

Basic Info

Drug Type
Shared antigen vaccine, Therapeutic vaccine
Synonyms
HER-Vaxx, HER2 cancer vaccine, Her VAXX
+ [5]
Target
Mechanism
HER2 antagonists(Receptor protein-tyrosine kinase erbB-2 antagonists), Immunostimulants
Inactive Indication-
Originator Organization
Active Organization
Inactive Organization-
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
AdenocarcinomaPhase 2
GE
30 Aug 2017
AdenocarcinomaPhase 2
UA
30 Aug 2017
AdenocarcinomaPhase 2
TW
30 Aug 2017
AdenocarcinomaPhase 2
MD
30 Aug 2017
AdenocarcinomaPhase 2
RS
30 Aug 2017
AdenocarcinomaPhase 2
IN
30 Aug 2017
AdenocarcinomaPhase 2
TH
30 Aug 2017
HER2-positive gastric cancerPhase 2
UA
30 Aug 2017
HER2-positive gastric cancerPhase 2
RS
30 Aug 2017
Gastrooesophageal junction cancerPhase 2
US
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
36
HER-Vaxx plus chemotherapy
(sqfikuihdr) = wnbnxdowyl dvvxipxeyf (zyzauemrui, 7.52 - 14.32)
Positive
16 Sep 2024
Chemotherapy alone
(sqfikuihdr) = fqiubuhwze dvvxipxeyf (zyzauemrui, 6.01 - 9.59)
Phase 2
36
HER-Vaxx + chemotherapy
(fqcavyghqj) = aarmfrqoky tdhljtejvd (fkuaxqgpms, 7.5 - 14.3)
Positive
05 Apr 2024
Chemotherapy
(fqcavyghqj) = euswtoztkx tdhljtejvd (fkuaxqgpms, 6.0 - 9.6)
Phase 2
32
HER-Vaxx 50 µg+chemotherapy
(pgfnpryhsf) = hdyxvvijht bbhrirduyx (xhrbgonfcd )
Positive
24 Jan 2023
chemotherapy
(pgfnpryhsf) = ozpsumnssg bbhrirduyx (xhrbgonfcd )
Phase 1/2
36
IMU-131+chemotherapy
(atphjmbevr) = tfddgprfbs lssfoiidqy (gbzfidozqo )
Positive
04 Dec 2022
chemotherapy
(atphjmbevr) = ldxnpsrunq lssfoiidqy (gbzfidozqo )
Phase 2
27
HER-Vaxx plus standard chemotherapy
(vbriggjhai): HR = 0.418 (80% CI, 0.186 - 0.942), P-Value = 0.083
Positive
03 Jul 2021
Standard chemotherapy alone
Phase 1
Advanced Gastric Adenocarcinoma
HER2/neu Overexpression
14
chemotherapy+HER2 cancer vaccine
(wdqokhfjxl) = none mcarwrcznf (lknpnqgtjq )
Positive
03 Jun 2019
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Regulation

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