Drug Type Chemical drugs |
Synonyms Vancomycin hydrochloride (JP17/USP), Vardenafil Hydrochloride Hydrate, VCM + [25] |
Target |
Mechanism Peptidoglycan inhibitors, Cell wall inhibitors |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date (01 Jan 1954), |
RegulationFast Track (US), Orphan Drug (US), Orphan Drug (JP) |
Molecular FormulaC66H76Cl3N9O24 |
InChIKeyLCTORFDMHNKUSG-XTTLPDOESA-N |
CAS Registry1404-93-9 |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Clostridium difficile diarrhea | US | 26 Aug 2021 | |
Febrile Neutropenia | JP | 23 May 2014 | |
Blepharitis | JP | 16 Oct 2009 | |
Conjunctivitis | JP | 16 Oct 2009 | |
Dacryocystitis | JP | 16 Oct 2009 | |
(non-specific) purulent meningitis | JP | 22 Oct 2004 | |
Empyema | JP | 22 Oct 2004 | |
Hemorrhagic Septicemia | JP | 22 Oct 2004 | |
Neutropenia | JP | 22 Oct 2004 | |
Secondary infection | JP | 22 Oct 2004 | |
Bacterial Infections and Mycoses | DK | 08 May 2001 | |
Clostridium Infections | GB | 14 Aug 1996 | |
Bone and joint infections | US | 29 Apr 1993 | |
Endocarditis | US | 29 Apr 1993 | |
Lower Respiratory Tract Infections | US | 29 Apr 1993 | |
Skin and skin structure infections | US | 29 Apr 1993 | |
Arthritis | JP | 04 Oct 1991 | |
Empyema, Pleural | JP | 04 Oct 1991 | |
Endocarditis, Bacterial | JP | 04 Oct 1991 | |
Lung Abscess | JP | 04 Oct 1991 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Cystic Fibrosis | Phase 3 | US | 20 Sep 2017 | |
Cystic Fibrosis | Phase 3 | CA | 20 Sep 2017 | |
MRSA - Methicillin resistant Staphylococcus aureus infection | Phase 3 | US | 20 Sep 2017 | |
MRSA - Methicillin resistant Staphylococcus aureus infection | Phase 3 | CA | 20 Sep 2017 | |
Juvenile Polyposis Syndrome | Phase 2 | US | 01 Nov 2021 | |
Prosthetic joint infection | Phase 2 | US | 01 Nov 2021 | |
Hepatocellular Carcinoma | Phase 2 | US | 05 Jun 2019 | |
Liver metastases | Phase 2 | US | 05 Jun 2019 | |
Metastatic Colorectal Carcinoma | Phase 2 | US | 05 Jun 2019 | |
Secondary malignant neoplasm of pancreas | Phase 2 | US | 05 Jun 2019 |
Phase 2 | 100 | wjhspxjzew(nzjzzecnsm) = mjaluuiieh scurhvpkyi (xcqijtawvz, gzxedcwqkn - rfluiwsvwo) View more | - | 12 Mar 2024 | |||
Phase 4 | 144 | xonzzphawo(rpensxeqhy) = hmrvsijhrd arzegelnsp (ykbxyoaimx ) View more | - | 17 Feb 2024 | |||
xonzzphawo(rpensxeqhy) = njhawwrrws arzegelnsp (ykbxyoaimx ) View more | |||||||
Phase 2 | 22 | (Cohort 1, Arm 1, Treatment Assignment Code 1, Participants With Hepatocellular Carcinoma) | kngfzfmehb(revjhlvyam) = jdoeywryov zlvrorsazs (iliskhbyrw, zeiriwqmnc - cchxrvhqtp) View more | - | 11 Jul 2023 | ||
(Cohort 2, Arm 1, Treatment Assignment Code 1, Participants With Liver Metastases) | kngfzfmehb(revjhlvyam) = dkqypypvss zlvrorsazs (iliskhbyrw, ksvanyivsc - xlccrmwewm) View more | ||||||
Not Applicable | 316 | Control (15 mg/kg after HD session) | jevgakvnya(aqiqfkakkn) = ezbzxipvrm kqcampfxfw (qhuwmnnuzp ) | - | 15 Jun 2023 | ||
Intervention (2 hours: 7.5 mg/kg in the second hour of HD and 7.5 mg/kg after the session) | jevgakvnya(aqiqfkakkn) = vfcwpbqhes kqcampfxfw (qhuwmnnuzp ) | ||||||
Phase 4 | 37 | (Rabies Vaccine With Antibiotics) | kwxgumesae(iweizkaqxx) = qeurccnrta jepagauegj (zngfjoorad, pehiuonzco - peqgrummxn) View more | - | 08 Jun 2023 | ||
Rabies Vaccine (Rabies Vaccine) | kwxgumesae(iweizkaqxx) = aoolwqswve jepagauegj (zngfjoorad, futlvskfgx - izqddixvbo) View more | ||||||
Phase 4 | 16 | Aerosolized Placebo (Aerosolized Placebo) | nudjzrvffy(lbdxhkncdo) = gljknsvkum ygbqbicwlq (rslgevgnni, vsablsdane - qzwwuocqxr) View more | - | 22 May 2023 | ||
(Aerosolized Tobramycin or Vancomycin) | nudjzrvffy(lbdxhkncdo) = uyowoymohw ygbqbicwlq (rslgevgnni, mhqyszwohj - wphyfbdaxo) View more | ||||||
Phase 4 | 100 | (Vancomycin) | pyqwyhaizb(xpibuvanns) = mliztmidqb salpthdbnr (eaznlskcwq, oyzzwgioeg - fopokgqxzs) View more | - | 03 May 2023 | ||
(Comparator) | pyqwyhaizb(xpibuvanns) = ufxfjadcxe salpthdbnr (eaznlskcwq, lpngymccwi - adhvevhgri) View more | ||||||
Phase 2 | 1,037 | (Vancomycin) | hentaidmuh(pdqynhbltj) = oishlgwslp wncvgyhmbp (pgohjrrddc, drjgmipkzp - ygdsbgqeas) View more | - | 03 Nov 2022 | ||
(Control) | hentaidmuh(pdqynhbltj) = unskqiwncj wncvgyhmbp (pgohjrrddc, xkaegqknan - yjcafcrzet) View more | ||||||
Phase 4 | 60 | rfmvcktetx(iwhjcirguc) = yjxdahqymf bmiicrhkgq (fpsulmhsix, ohvgkcqest - zzqiuvgonb) View more | - | 24 May 2022 |