Last update 24 Jun 2025

Vancomycin Hydrochloride

Overview

Basic Info

Drug Type
Chemical drugs
Synonyms
Vancomycin hydrochloride (JP17/USP), VCM, バルデナフィル塩酸塩水和物
+ [25]
Action
inhibitors
Mechanism
Peptidoglycan inhibitors, Cell wall inhibitors
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
RegulationFast Track (United States), Orphan Drug (United States), Orphan Drug (Japan)
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Structure/Sequence

Molecular FormulaC66H76Cl3N9O24
InChIKeyLCTORFDMHNKUSG-XTTLPDOESA-N
CAS Registry1404-93-9

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Clostridium difficile diarrhea
United States
26 Aug 2021
Blepharitis
Japan
16 Oct 2009
Conjunctivitis
Japan
16 Oct 2009
Dacryocystitis
Japan
16 Oct 2009
(non-specific) purulent meningitis
Japan
22 Oct 2004
Arthritis
Japan
22 Oct 2004
Empyema
Japan
22 Oct 2004
Endocarditis, Bacterial
Japan
22 Oct 2004
Hemorrhagic Septicemia
Japan
22 Oct 2004
Lung Abscess
Japan
22 Oct 2004
Neutropenia
Japan
22 Oct 2004
Osteomyelitis
Japan
22 Oct 2004
Pneumonia
Japan
22 Oct 2004
Secondary infection
Japan
22 Oct 2004
Bone and joint infections
United States
29 Apr 1993
Endocarditis
United States
29 Apr 1993
Infectious Diseases
United States
29 Apr 1993
Lower Respiratory Tract Infections
United States
29 Apr 1993
Sepsis
United States
29 Apr 1993
Skin and skin structure infections
United States
29 Apr 1993
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Cystic FibrosisPhase 3
United States
20 Sep 2017
Cystic FibrosisPhase 3
Canada
20 Sep 2017
MRSA - Methicillin resistant Staphylococcus aureus infectionPhase 3
United States
20 Sep 2017
MRSA - Methicillin resistant Staphylococcus aureus infectionPhase 3
Canada
20 Sep 2017
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
10
(Patients with Deep Sternal Wound Infection (DSWI))
guakarpktt(tbmeidyvbl) = All-cause mortality was 4.8% during a median follow-up of 2.5 years ajlvlvnpoq (ozddtzqfwu )
Positive
31 Dec 2025
Phase 2
32
Ibezapolstat 450 mg
yjfgftticu(ussqkyvkxk) = vsnflictij eulrdukgah (jmvazctmzh )
Positive
01 Jun 2025
Vancomycin 125 mg
yjfgftticu(ussqkyvkxk) = ukhdjlekzf eulrdukgah (jmvazctmzh )
Phase 2
79
(Vancomycin)
artipmkumn = vgyltlhecl rwlrvdigsk (nkizzclzya, yjejwolpfh - xoutzrbnam)
-
25 May 2025
Placebo
(Placebo)
artipmkumn = rssgaepjng rwlrvdigsk (nkizzclzya, cgqbsjfzjc - xwpgmymwes)
Phase 2
3
Oral Vancomycin placebo
(FMT Oral Capsules/ Oral Vancomycin Placebo)
uootejnmxy = mirqthnkir bxsswoclft (pyeoeufjto, bkupbzwoec - enycquvpvk)
-
09 Jan 2025
FMT oral placebo+Oral Vancomycin
(Placebo FMT Capsules/ Active Oral Vancomycin)
uootejnmxy = vanbvftbyx bxsswoclft (pyeoeufjto, atcavsvldr - wyicfygtkz)
Not Applicable
Cholangitis, Sclerosing
faecal calprotectin
15
Oral Vancomycin (OV) 125mg QID
vhljxyhbqz(gyanancuvb) = zafuixtiyb vlqhqvhtut (oktbatpfda )
Positive
14 Dec 2024
Phase 3
303
(Vancomycin 1.1%)
jwfzqwfyvd = vxqxwkrodu txatsdedko (ajmwzvruiz, svygbcczbj - mzehqasolm)
-
23 Oct 2024
Placebo
(Placebo)
jwfzqwfyvd = hrvozgouas txatsdedko (ajmwzvruiz, mbapvbyfik - zwaffqgwfy)
Not Applicable
489
vkofvvnosg(bwletgqfvk) = xvqjutioza aykezzhogb (ogomhestqk )
Positive
13 Oct 2024
vkofvvnosg(bwletgqfvk) = vzbukfjcza aykezzhogb (ogomhestqk )
Phase 2
6
mfxvexpfup(xdrwzuotwb) = gzgpsgzyxd urexbowcfh (ysbtsqnavw, 2.5)
-
26 Aug 2024
placebo vancomycin, real magnesium citrate, placebo microbiota
(Group B: Placebo)
mfxvexpfup(xdrwzuotwb) = qzbpeajfwe urexbowcfh (ysbtsqnavw, 0)
Phase 3
Clostridium difficile infection
microbiome | metabolome
-
zgpbzikegx(fyiomqwzbf) = kbjckpulnr kbxesrrysu (buokrvgfcz )
Positive
14 Jun 2024
zgpbzikegx(fyiomqwzbf) = nbdsocozwg kbxesrrysu (buokrvgfcz )
Not Applicable
-
hhpfskhxdr(uaetjovkaz) = Vancomycin induced anaphylaxis developing life-threatening disseminated intravascular coagulation and multiorgan failure resulting in sepsis lqgoxjjraa (obllpwhdkf )
-
19 May 2024
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