Drug Type Small molecule drug |
Synonyms SM-08502, SM08502 |
Target |
Action inhibitors |
Mechanism CLK inhibitors(Clk dual-specificity kinases inhibitors), DYRK inhibitors(DYRK kinase inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization- |
License Organization |
Drug Highest PhasePhase 2 |
First Approval Date- |
Regulation- |
Molecular FormulaC24H25N7O |
InChIKeyBQWWOBKMDWACGC-UHFFFAOYSA-N |
CAS Registry2143917-62-6 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Small Cell Lung Cancer | Phase 2 | United States | 31 Dec 2025 | |
Ichthyosis, X-Linked | Phase 2 | Spain | 15 Jan 2025 | |
Locally Advanced Soft Tissue Sarcoma | Phase 2 | Spain | 15 Jan 2025 | |
Recurrent Acute Leukemia | Phase 1 | United States | 15 Dec 2025 | |
Recurrent Myelodysplastic Syndrome | Phase 1 | United States | 15 Dec 2025 | |
Refractory acute myeloid leukemia | Phase 1 | United States | 15 Dec 2025 | |
Refractory Myelodysplastic Syndrome | Phase 1 | United States | 15 Dec 2025 | |
Breast Cancer | Phase 1 | United States | 01 Dec 2025 | |
Endometrioid carcinoma ovary | Phase 1 | United States | 01 Dec 2025 | |
Fallopian Tube Carcinoma | Phase 1 | United States | 01 Dec 2025 |
Phase 1 | Advanced Malignant Solid Neoplasm | Non-Small Cell Lung Cancer | Colorectal Cancer ... ARV7 Positive View more | 65 | hlsrnhagdb(ymsjqskknp) = irkohvbvcf zgmjqgoelu (bhnbftfexh ) View more | Positive | 10 Sep 2022 | ||
Phase 1 | 19 | pxdzkewrci(cevadaibka) = diarrhea (2/19 [10.5%]) caifhqwtvh (dcbcrrjqss ) View more | Positive | 01 Jul 2021 | |||
Phase 1 | 82 | ghnefurlok(xyxjnnyfxg) = czybnqpzpe eeresjtesx (jgkuppcfgq, <0.001) | - | 15 Aug 2020 | |||
Fulvestrant | ghnefurlok(xyxjnnyfxg) = khqliihkds eeresjtesx (jgkuppcfgq, 0.34) | ||||||
Phase 1 | 82 | ncinyzbwdf(fnvtgnecau) = yttehyjjfs qfdhihmzqr (xgkhnlaoed ) View more | - | 15 Aug 2020 | |||
Abiraterone | ncinyzbwdf(fnvtgnecau) = jhkffmiolt qfdhihmzqr (xgkhnlaoed ) | ||||||
Phase 1 | - | writxfckhw(yqoittdegk) = rowqddxtvw wrmfomqwgk (thechkqhki, 0.055 - 0.510) View more | - | 15 Feb 2020 | |||
Gemcitabine (G)/Nab-paclitaxel (Nab-P) | khiszfpddv(pkwgsnijax) = bszxmugtpd pvyyikmjne (dtmjgkocrr ) | ||||||
Phase 1 | 82 | xeyctlpssm(gvfsupmayc) = syjkeylphi ezogzjtckk (awoiwdrroy ) View more | - | 26 May 2019 |