Last update 05 Apr 2024

Zimlovisertib

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
PF 6650833, PF-06650833, PF-6650833
Target
Mechanism
IRAK4 inhibitors(Interleukin-1 receptor-associated kinase 4 inhibitors)
Active Indication-
Originator Organization
Active Organization
Inactive Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-

Structure

Molecular FormulaC18H20FN3O4
InChIKeyJKDGKIBAOAFRPJ-ZBINZKHDSA-N
CAS Registry1817626-54-2

External Link

KEGGWikiATCDrug Bank
---

R&D Status

IndicationHighest PhaseCountry/LocationOrganization
COVID-19PendingUS
More
Lupus VulgarisPendingUS
More
Rheumatoid ArthritisPendingBA
More
COVID-19 respiratory infectionPendingUS
More
-
Hidradenitis SuppurativaPendingAU
More
Login to view more data

Clinical Trial Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
194
lazxloeiho(msoftgdoxz) = vuwclrtugw nvtiyaimxz (jqmiidauyj, nopezysoyx - jvfvcovsgy)
-
15 Jun 2023
(PF-06650833 400mg QD)
lazxloeiho(msoftgdoxz) = tmqqnsvyzy nvtiyaimxz (jqmiidauyj, hlkyppvgfr - ebybzspnsi)
Phase 2
460
(PF-06650833 400mg MR + Tofacitinib 11mg MR)
ufcyjiqycs(erjdhvtbqz) = dooshkjoox tmkwgsjcpy (jshflkeuqg, vospifavdl - lxpmtkqjpw)
-
07 Apr 2023
(PF-06650833 400mg MR + PF-06651600 100mg)
ufcyjiqycs(erjdhvtbqz) = upksbyipfe tmkwgsjcpy (jshflkeuqg, xhdpkgpjap - vkysgeseex)
Phase 2
269
Placebo
vpplyvlhzh(yevcunzimm) = majcwbuvza slkmhdeedd (geazsehbmv, xifyibvjwz - luvblfulmm)
-
27 Feb 2020
Phase 1
-
-
ckzotgtiwa(fcoqqhmfwz) = PF-06650833 was generally well tolerated, with no dose-limiting treatment-emergent adverse events (TEAEs) identified in either study. rbobvjqlvq (aawacnzwny )
Positive
05 Dec 2019
Placebo
Login to view more data

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial Analysis

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Leverages most recent intelligence information, enabling fullest potential.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free