Drug Type Small molecule drug |
Synonyms Compound edaravone, Edaravone and Dexborneol, Edaravone combination + [12] |
Target- |
Mechanism Neuroprotectants |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date CN (29 Jul 2020), |
RegulationBreakthrough Therapy (CN), Special Review Project (CN), Breakthrough Therapy (US) |
Molecular FormulaC10H22O |
InChIKeyACUZDYFTRHEKOS-JTQLQIEISA-N |
CAS Registry33758-16-6 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | - | - |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Acute Ischemic Stroke | CN | 01 Dec 2024 | |
Brain Infarction | CN | 29 Jul 2020 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Cognitive Dysfunction | Phase 2 | CN | 03 Apr 2024 | |
Cerebral Hemorrhage | Phase 2 | - | 01 Mar 2021 | |
Intracranial Hemorrhages | Phase 1 | US | 25 Oct 2018 | |
Amyotrophic Lateral Sclerosis | IND Application | US | - | |
Cognition Disorders | IND Application | US | - |
Phase 3 | 914 | flyzeeghia(yrydftxadf) = gtxkskonwz wqglpstfxt (dcobqdzpwc ) View more | Positive | 19 Feb 2024 | |||
Placebo | flyzeeghia(yrydftxadf) = lqjsuznloy wqglpstfxt (dcobqdzpwc ) View more | ||||||
Phase 3 | - | xbmdyweixg(fcebmutlqm) = 初步分析显示,相对于安慰剂, 先必新舌下片显著改善AIS患者治疗后神经功能恢复及独立生活能力,达到预期疗效终点 dknzpxxgir (pomqfslnhf ) Met | Positive | 01 Dec 2022 | |||
Placebo | |||||||
NEWS Manual | Not Applicable | 94 | (gtupwljtul) = uxsvrqhrxe kbwwmoudkb (yekcreauvf, 4.11) View more | Positive | 06 May 2022 | ||
(gtupwljtul) = nztyawtrbz kbwwmoudkb (yekcreauvf, 2.15) View more | |||||||
Phase 3 | 1,165 | Edaravone+Dexborneol | xhsxonzxkp(qnsnsmxcbk) = awddmthnbz ajmfbwecmc (jwfsqggvuy ) View more | Superior | 01 Mar 2021 | ||
Edaravone | xhsxonzxkp(qnsnsmxcbk) = uhdtgdrldi ajmfbwecmc (jwfsqggvuy ) | ||||||
NCT01929096 (Pubmed) Manual | Phase 2 | 385 | pqtgqetgit(xnmautuzik): P-Value = 0.6799 View more | Positive | 22 Apr 2019 | ||
Edaravone |