Last update 01 Nov 2024

Pimasertib Hydrochloride/Voxtalisib

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms-
Target
MEK1 x MEK2 x PI3Kα x mTORC1 x mTORC2
Mechanism
MEK1 inhibitors(Dual specificity mitogen-activated protein kinase kinase 1 inhibitors), MEK2 inhibitors(Dual specificity mitogen-activated protein kinase kinase 2 inhibitors), PI3Kα inhibitors(Phosphatidylinositol 3 kinase alpha inhibitors)
+ [2]
Therapeutic Areas
Neoplasms
Active Indication
Solid tumor
Inactive Indication
Ovarian Cancer
Originator Organization
Merck & Co., Inc.Merck & Co., Inc.
Active Organization
Day One Biopharmaceuticals, Inc.
Inactive Organization
SanofiSanofiMerck & Co., Inc.Merck & Co., Inc.
Drug Highest PhasePhase 1/2
First Approval Date-
Regulation-
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Structure

Molecular FormulaC15H16ClFIN3O3
InChIKeyHIEXZUXKTABHCP-PPHPATTJSA-N
CAS Registry1236361-78-6
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Related

100 Clinical Results associated with Pimasertib Hydrochloride/Voxtalisib
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100 Translational Medicine associated with Pimasertib Hydrochloride/Voxtalisib
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100 Patents (Medical) associated with Pimasertib Hydrochloride/Voxtalisib
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100 Deals associated with Pimasertib Hydrochloride/Voxtalisib
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Solid tumorPhase 2-
Day One Biopharmaceuticals, Inc.
-
Ovarian CancerPreclinical-
SanofiSanofi
-
Ovarian CancerPreclinical-
Merck & Co., Inc.Merck & Co., Inc.
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Deal

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Clinical Trial

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Approval

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Regulation

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