Last update 01 Jul 2024

S-64315

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
MIK 665, MIK-665, S 64315
+ [1]
Target
Mechanism
Mcl-1 inhibitors(Induced myeloid leukemia cell differentiation protein Mcl-1 inhibitors)
Inactive Indication
Originator Organization
Inactive Organization-
Drug Highest PhasePhase 1/2
First Approval Date-
Regulation-

Structure

Molecular FormulaC47H44ClFN6O6S
InChIKeyPKYIMGFMRFVOMB-UHFFFAOYSA-N
CAS Registry1799631-75-6

R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Hematologic NeoplasmsPhase 2
FR
30 Jan 2022
Hematologic NeoplasmsPhase 2
FR
30 Jan 2022
Hematologic NeoplasmsPhase 2
FR
30 Jan 2022
Acute Myeloid LeukemiaPhase 2
US
17 Feb 2021
Acute Myeloid LeukemiaPhase 2
AU
17 Feb 2021
Acute Myeloid LeukemiaPhase 2
FR
17 Feb 2021
Acute Myeloid LeukemiaPhase 2
ES
17 Feb 2021
Non-Hodgkin's lymphoma refractoryPhase 1
US
23 Jun 2021
Non-Hodgkin's lymphoma refractoryPhase 1
JP
23 Jun 2021
Non-Hodgkin's lymphoma refractoryPhase 1
BE
23 Jun 2021
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1/2
17
MIK665+Azacitidine
(50 mg S64315 (Also Referred as MIK665) With Azacitidine)
lvzerxslff(rwbfkixyim) = mwwdhohger uunorqkldk (yftbawprhc, dfayciddoe - cxurblewmv)
-
06 Jun 2024
MIK665+Azacitidine
(100 mg S64315 (Also Referred as MIK665) With Azacitidine)
lvzerxslff(rwbfkixyim) = mqjqeozrum uunorqkldk (yftbawprhc, blnkrxhlwt - yqfgfyladd)
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Approval

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Regulation

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