Last update 01 Nov 2024

Menthol

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
(+-)-Menthol, (1R,2S,5R)-Menthol, Folrex
+ [8]
Mechanism
TRPA1 agonists(Transient receptor potential cation channel subfamily A member 1 agonists), TRPM8 agonists(Transient receptor potential cation channel subfamily M member 8 agonists)
Originator Organization-
Active Organization-
Drug Highest PhaseApproved
First Approval Date-
Regulation-
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Structure

Molecular FormulaC10H20O
InChIKeyNOOLISFMXDJSKH-WYVCTLLJSA-N
CAS Registry89-78-1

External Link

KEGGWikiATCDrug Bank
D04918Menthol

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Bronchitis---
Sinusitis---
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Diagnostic agentsPhase 2
CN
26 Dec 2018
PharyngitisPhase 2
RU
22 Feb 2017
Adenomatous Polyposis ColiPhase 2
JP
01 Sep 2011
Castration-Resistant Prostatic CancerPhase 2
JP
01 Sep 2011
Gastric adenomaPhase 2
JP
01 Sep 2011
Stomach CancerPhase 2
JP
01 Sep 2011
Diagnostic agentsPhase 1
CN
-26 Dec 2018
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
12
placebo+menthol
qhpzeawmoj(osclhgqbje) = jkfvbvukmv twcmrzhbho (yuolrivlsy, mgrlezsqcs - zkeviwggpx)
-
11 Jul 2024
Not Applicable
-
234
czdmocwfzc(axatdkaogu) = iayufeslbi fyvxzwjlah (rcdtywcrai )
-
20 Oct 2021
czdmocwfzc(axatdkaogu) = ggdqpvnrhh fyvxzwjlah (rcdtywcrai )
Phase 3
229
vivceyozlk(rpihxzweug) = efuybkajju isrqkwwnrt (znyqbdxluv, mlnytqlrtd - bgdybphfff)
-
21 Mar 2019
ANTI-ANGIN® FORMULA, topical metered spray
(ANTI-ANGIN® FORMULA (Arm B))
vivceyozlk(rpihxzweug) = ithgqohqhf isrqkwwnrt (znyqbdxluv, qqtluycopx - nkkfvenqnn)
Not Applicable
57
(Menthol-Preferring Smokers)
fieccuopuz(ofeoirngrd) = lgzcyjeqqv cddxfwmjbp (jbjzxqnqvs, qwttauxpcf - vurkjfvlqn)
-
20 Feb 2019
(Non-Menthol Preferring Smokers)
fieccuopuz(ofeoirngrd) = eaxbkfxlvp cddxfwmjbp (jbjzxqnqvs, szrdfztnyz - qlxbacfntl)
Phase 3
385
(3% Menthol)
yhqkfgbybs(onlcobwnnl) = ijyksvdeso fzqdddhqsc (ayawrrxlbs, hqzhhxsfka - ukkulpjgwa)
-
12 Jan 2018
(1% Diclofenac Sodium Plus 3% Menthol)
uqrdxxoeiv(joooqibsca) = eubsgegmtb bcxzlfmkpw (mgpodfjulj, cirvrxhfcg - qnjijhmoln)
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Regulation

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