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Last update 09 May 2026
Nilvanstomig
Last update 09 May 2026
Overview
Basic Info
Drug Type Bispecific antibody |
Synonyms ZG-005, ZG005 |
Target |
Action inhibitors |
Mechanism PD-1 inhibitors(Programmed cell death protein 1 inhibitors), TIGIT inhibitors(T cell immunoglobulin and ITIM domains inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization- |
License Organization- |
Drug Highest PhasePhase 2 |
First Approval Date- |
Regulation- |
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Structure/Sequence
Sequence Code 453608435
Source: *****
Sequence Code 453608436
Source: *****
Related
15
Clinical Trials associated with NilvanstomigNCT07099547
A Study to Evaluate the Efficacy and Safety of ZG005 in Combination With Platinum-Based Chemotherapy as First-Line Treatment in Participants With Advanced Biliary Tract Carcinoma
NCT07080216
A Multicenter, Open-label, Dose-finding and Dose-expansion Phase I/II Study of ZG005 in Combination With Gecacitinib in Participants With Advanced Cervical Cancer
NCT07038096
A Phase Ib/II Study of the Tolerability, Safety, Efficacy, and Pharmacokinetics of ZG006 in Combination With ZG005 in Participants With Advanced Small Cell Lung Cancer or Neuroendocrine Carcinoma(NEC)
100 Clinical Results associated with Nilvanstomig
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100 Translational Medicine associated with Nilvanstomig
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100 Patents (Medical) associated with Nilvanstomig
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100 Deals associated with Nilvanstomig
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R&D Status
10 top R&D records. to view more data
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Biliary Tract Neoplasms | Phase 2 | China | 02 Dec 2025 | |
| Advanced biliary tract cancer | Phase 2 | China | 11 Nov 2025 | |
| Gallbladder Neoplasms | Phase 2 | China | 11 Nov 2025 | |
| Small Cell Lung Cancer | Phase 2 | China | 23 Sep 2025 | |
| Advanced Lung Small Cell Carcinoma | Phase 2 | China | 04 Sep 2025 | |
| Advanced Malignant Solid Neoplasm | Phase 2 | China | 29 May 2025 | |
| Advanced Lung Non-Small Cell Carcinoma | Phase 2 | China | 08 May 2025 | |
| Recurrent Lymphoma | Phase 2 | China | 28 Apr 2025 | |
| Refractory Lymphoma | Phase 2 | China | 28 Apr 2025 | |
| Classical Hodgkin's Lymphoma | Phase 2 | China | 21 Apr 2025 |
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Clinical Result
Clinical Result
Indication
Phase
Evaluation
View All Results
| - | Advanced Cervical Carcinoma First line | 60 | ngjhrqaatg(cxvxjyjdxa) = zsnlldamuh rjdakkaryh (neejscenky ) View more | Positive | 31 Oct 2025 | ||
sbdjbuiamc(jflrancxtv) = llqkikawyc zuwkthqcjc (hvhescjvcv ) View more | |||||||
Phase 1 | 21 | jdfhwcihin(mkqvvhixyc) = uvhwnvelnd ydedqzjknx (fahvhlhptm ) View more | Positive | 31 Oct 2025 | |||
Phase 1/2 | Advanced Neuroendocrine Carcinoma First line | 39 | mopqyaajwf(kzopbgiwbc) = No dose-limiting toxicities (DLT) were observed in part 1 xfnsclsejk (nstirxtmay ) View more | Positive | 17 Oct 2025 | ||
Phase 1/2 | Advanced Neuroendocrine Carcinoma First line | 84 | kktrbmlnpj(sdoqtkmrrn) = xcnirizeen rnkeqvdwbc (ikcpmwktwc ) View more | Positive | 11 Sep 2025 | ||
kktrbmlnpj(sdoqtkmrrn) = wnqwktxslo rnkeqvdwbc (ikcpmwktwc ) View more | |||||||
Phase 1/2 | Advanced Cervical Carcinoma Second line | 55 | irmtsoqoxi(vfpxbbelts) = ncxxpoifob rudtehuxfe (dlcsajpxtv ) View more | Positive | 30 May 2025 | ||
uvuiwqlceg(orbeacnfbo) = wktcwvarnf tfofimvuyt (aogsyaxxpb ) View more | |||||||
Phase 1/2 | Advanced Cervical Carcinoma First line | 41 | tanigzvsiw(newpraauin) = 1 SAE of bilateral lung pneumonia in the 10 mg/kg group was assessed related to ZG005 by the investigator dnszktymhy (oqdkgzxtmy ) | Positive | 30 May 2025 | ||
CTR20220021 (NEWS) Manual  | Phase 1/2 | 46 | iftxjqmszs(xxhqqjvece) = gslfxzbbfm bnloownbfd (yiczrwreyy ) View more | Positive | 25 Sep 2024 | ||
(20 mg/kg) | iftxjqmszs(xxhqqjvece) = hjtfzwzxor bnloownbfd (yiczrwreyy ) View more | ||||||
Not Applicable | Advanced Hepatocellular Carcinoma First line | 10 | smogpxqdde(qhogaebppa) = syqzwphnip lxzlhcvuiq (avstvwssyl ) View more | Positive | 25 Sep 2024 | ||
CTR20220021 (ASCO2024) Manual | Phase 1 | 57 | ccvbodltay(jfmlyugekx) = moaaazlgzx awsycwlceu (ulseqfiowe ) View more | Positive | 24 May 2024 | ||
(cervical cancer) | ccvbodltay(jfmlyugekx) = bunjjdcylb awsycwlceu (ulseqfiowe ) View more | ||||||
Phase 1 | 16 | ndhbkoulmp(gljeecmgsd) = viqcaxatyp favhodghbz (lfzkgbrowg ) View more | Positive | 26 May 2023 |
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