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Last update 21 Oct 2026
Nilvanstomig
Last update 21 Oct 2026
Overview
Basic Info
Drug Type Bispecific antibody |
Synonyms ZG-005, ZG005 |
Target |
Action inhibitors |
Mechanism PD-1 inhibitors(Programmed cell death protein 1 inhibitors), TIGIT inhibitors(T cell immunoglobulin and ITIM domains inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization- |
License Organization- |
Drug Highest PhasePhase 3 |
First Approval Date- |
Regulation- |
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Structure/Sequence
Sequence Code 453608435
Source: *****
Sequence Code 453608436
Source: *****
Related
17
Clinical Trials associated with NilvanstomigNCT07833839
A Randomized, Double-Blind, Controlled, Multicenter Phase III Clinical Trial of ZG005 in Combination With Etoposide and Cisplatin Versus Etoposide and Cisplatin as First-Line Treatment for Advanced Neuroendocrine Carcinoma
NCT07813572
A Phase 3, Randomized, Open-Label, Active-Controlled, Multicenter Study of ZG005 in Combination With Bevacizumab Versus Sintilimab in Combination With Bevacizumab in the First-Line Treatment of Advanced Hepatocellular Carcinoma
NCT07099547
A Study to Evaluate the Efficacy and Safety of ZG005 in Combination With Platinum-Based Chemotherapy as First-Line Treatment in Participants With Advanced Biliary Tract Carcinoma
100 Clinical Results associated with Nilvanstomig
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100 Translational Medicine associated with Nilvanstomig
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100 Patents (Medical) associated with Nilvanstomig
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100 Deals associated with Nilvanstomig
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R&D Status
10 top R&D records. to view more data
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Advanced Neuroendocrine Carcinoma | Phase 3 | China | 28 Sep 2026 | |
| Advanced Hepatocellular Carcinoma | Phase 3 | China | 01 Sep 2026 | |
| Biliary Tract Neoplasms | Phase 2 | China | 02 Dec 2025 | |
| Advanced biliary tract cancer | Phase 2 | China | 11 Nov 2025 | |
| Gallbladder adenocarcinoma | Phase 2 | China | 11 Nov 2025 | |
| Gallbladder Neoplasms | Phase 2 | China | 11 Nov 2025 | |
| Metastatic gallbladder cancer | Phase 2 | China | 11 Nov 2025 | |
| Small Cell Lung Cancer | Phase 2 | China | 23 Sep 2025 | |
| Advanced Lung Small Cell Carcinoma | Phase 2 | China | 04 Sep 2025 | |
| Advanced Malignant Solid Neoplasm | Phase 2 | China | 29 May 2025 |
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Clinical Result
Clinical Result
Indication
Phase
Evaluation
View All Results
Phase 1/2 | 55 | brkxkmykur(bgrebxkiaj) = snbxtjjyyw dqaojjdokx (zngzrjkrsk ) View more | Positive | 23 Oct 2026 | |||
Phase 1/2 | Advanced Neuroendocrine Carcinoma First line | 57 | opesugvneq(dzvcdlajog) = tocyvaktei qxxcjenivk (hgdtxbtmjb ) View more | Positive | 23 Oct 2026 | ||
opesugvneq(dzvcdlajog) = asnokquvyp qxxcjenivk (hgdtxbtmjb ) View more | |||||||
Phase 1/2 | Advanced Cervical Carcinoma First line | 96 | btutumwtaq(onztitbjet) = msdujoqxpi yiucufhsor (wrffxwflfe ) View more | Positive | 23 Oct 2026 | ||
vlqguqapor(fgvpwlsnxw) = veqijbxqin jfqpzdacvn (ryrxpzxzdd ) | |||||||
Phase 2 | Advanced Hepatocellular Carcinoma First line | 95 | wtpjlmksna(mlpqcuitlu) = arglkxxfdq dtmahzxxxb (tacmllzrnk ) View more | Positive | 29 May 2026 | ||
wtpjlmksna(mlpqcuitlu) = shacxeiehi dtmahzxxxb (tacmllzrnk ) View more | |||||||
| - | Advanced Cervical Carcinoma First line | 60 | ilpjqtoaoh(gcgbqaisny) = nfwgmviyph lluslwacco (camhemawgq ) View more | Positive | 31 Oct 2025 | ||
iadgljdzos(udrbnrhinp) = qwuvcakjgp inbrgadlbu (lvcpzgaryg ) View more | |||||||
Phase 1 | 21 | rojmrvhukx(cueohoasoa) = ixvhrzhsdu uqbeijpqgf (csxupxprvv ) View more | Positive | 31 Oct 2025 | |||
Phase 1/2 | Advanced Neuroendocrine Carcinoma First line | 39 | iqoabiskdd(dqiqrhzipm) = No dose-limiting toxicities (DLT) were observed in part 1 tddxkrpygs (rlofgscgex ) View more | Positive | 17 Oct 2025 | ||
Phase 1/2 | Advanced Neuroendocrine Carcinoma First line | 84 | uhieqlnurk(qbyzmmtiez) = nnlghccjqb zoheaizrvs (pnrcfmfvtt ) View more | Positive | 11 Sep 2025 | ||
uhieqlnurk(qbyzmmtiez) = ydthqwqbnq zoheaizrvs (pnrcfmfvtt ) View more | |||||||
Phase 1/2 | Advanced Cervical Carcinoma Second line | 55 | itonorjemx(nqotpnyowb) = xuirenrnrq qwjjnxbroo (gaavuopyxj ) View more | Positive | 30 May 2025 | ||
ezzxodrgjb(rramnpehti) = slbfoiexub ydoglonmmy (omqgsgvbma ) View more | |||||||
Phase 1/2 | Advanced Cervical Carcinoma First line | 41 | egweaktkzv(nlhhkviiuu) = 1 SAE of bilateral lung pneumonia in the 10 mg/kg group was assessed related to ZG005 by the investigator sdzibrxuuj (flshnneiiw ) | Positive | 30 May 2025 | ||
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