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Last update 29 Mar 2025
ZG-005
Last update 29 Mar 2025
Overview
Basic Info
Drug Type Bispecific antibody |
Synonyms ZG-005, ZG005 |
Target |
Action inhibitors |
Mechanism PD-1 inhibitors(Programmed cell death protein 1 inhibitors), TIGIT inhibitors(T cell immunoglobulin and ITIM domains inhibitors) |
Therapeutic Areas |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization- |
Drug Highest PhasePhase 2 |
First Approval Date- |
Regulation- |
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Related
16
Clinical Trials associated with ZG-005NCT06883526
A Multicenter, Open-Label, Dose-Escalation and Dose-Expansion Phase I/II Study of ZG005 in Combination With Gecacitinib in Patients With Relapsed or Refractory Lymphoma
NCT06558227
A Multicenter, Randomized, Open-label Phase II Study of ZG005 Combined With Bevacizumab Versus Sintilimab Combined With Bevacizumab for First-line Treatment of Advanced Hepatocellular Carcinoma
CTR20243067
ZG005联合贝伐珠单抗对照信迪利单抗联合贝伐珠单抗用于晚期肝细胞癌一线治疗的多中心、随机、开放的II期临床研究
[Translation] A multicenter, randomized, open-label phase II clinical study of ZG005 combined with bevacizumab versus sintilimab combined with bevacizumab for first-line treatment of advanced hepatocellular carcinoma
100 Clinical Results associated with ZG-005
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100 Translational Medicine associated with ZG-005
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100 Patents (Medical) associated with ZG-005
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100 Deals associated with ZG-005
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R&D Status
10 top R&D records. to view more data
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Advanced Malignant Solid Neoplasm | Phase 2 | China | 26 Mar 2025 | |
| Advanced Lung Non-Small Cell Carcinoma | Phase 2 | China | 25 Mar 2025 | |
| Recurrent Lymphoma | Phase 2 | China | 13 Mar 2025 | |
| Refractory Lymphoma | Phase 2 | China | 13 Mar 2025 | |
| Advanced biliary tract cancer | Phase 2 | China | 04 Mar 2025 | |
| Advanced Hepatocellular Carcinoma | Phase 2 | China | 22 Oct 2024 | |
| Advanced Neuroendocrine Carcinoma | Phase 2 | China | 24 May 2024 | |
| Advanced Cervical Carcinoma | Phase 2 | China | 18 Mar 2024 | |
| Solid tumor | Phase 2 | - | - |
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Clinical Result
Clinical Result
Indication
Phase
Evaluation
View All Results
CTR20220021 (NEWS) Manual  | Phase 1/2 | 46 | vlglvoyjws(ehvvazgnyw) = oodberevsn etoxxlxjax (pcojcqwwwn ) View more | Positive | 25 Sep 2024 | ||
(20 mg/kg) | vlglvoyjws(ehvvazgnyw) = tpauauaufv etoxxlxjax (pcojcqwwwn ) View more | ||||||
Not Applicable | Advanced Hepatocellular Carcinoma First line | 10 | hakgehmzge(qkmtwqebwy) = tnfketfsgd omhapvljzm (aoogaodadg ) View more | Positive | 25 Sep 2024 | ||
CTR20220021 (ASCO2024) Manual | Phase 1 | 57 | ymkurcawct(phekqumnyk) = eanclhehww ikbokohkwj (nqutdfyjen ) View more | Positive | 24 May 2024 | ||
(cervical cancer) | ymkurcawct(phekqumnyk) = jctrnxksei ikbokohkwj (nqutdfyjen ) View more | ||||||
Phase 1 | 16 | xgezcdbsui(npbmjmwztt) = gxmpwpeihe fsgtllkrsr (omcyqnwmur ) View more | Positive | 26 May 2023 |
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