Request Demo
Last update 11 Dec 2025
Nilvanstomig
Last update 11 Dec 2025
Overview
Basic Info
Drug Type Bispecific antibody |
Synonyms ZG-005, ZG005 |
Target |
Action inhibitors |
Mechanism PD-1 inhibitors(Programmed cell death protein 1 inhibitors), TIGIT inhibitors(T cell immunoglobulin and ITIM domains inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization- |
License Organization- |
Drug Highest PhasePhase 2 |
First Approval Date- |
Regulation- |
Login to view timeline
Related
20
Clinical Trials associated with NilvanstomigCTR20250739
ZG005 联合含铂化疗方案一线治疗晚期胆道癌患者的有效性及安全性的临床研究
[Translation] Clinical study on the efficacy and safety of ZG005 combined with platinum-containing chemotherapy as first-line treatment for patients with advanced biliary tract cancer
CTR20252686
ZG005 联合盐酸吉卡昔替尼片在晚期宫颈癌患者中的多中心、开放、剂量探索和剂量扩展的I/II 期临床研究
[Translation] A multicenter, open-label, dose-finding and dose-expansion phase I/II clinical study of ZG005 combined with gecaxitinib hydrochloride tablets in patients with advanced cervical cancer
NCT07099547
A Study to Evaluate the Efficacy and Safety of ZG005 in Combination With Platinum-Based Chemotherapy as First-Line Treatment in Participants With Advanced Biliary Tract Carcinoma
100 Clinical Results associated with Nilvanstomig
Login to view more data
100 Translational Medicine associated with Nilvanstomig
Login to view more data
100 Patents (Medical) associated with Nilvanstomig
Login to view more data
100 Deals associated with Nilvanstomig
Login to view more data
R&D Status
10 top R&D records. to view more data
Login
| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Advanced biliary tract cancer | Phase 2 | China | 11 Nov 2025 | |
| Advanced Lung Small Cell Carcinoma | Phase 2 | China | 04 Sep 2025 | |
| Biliary Tract Neoplasms | Phase 2 | China | 01 Sep 2025 | |
| Gallbladder Neoplasms | Phase 2 | China | 01 Sep 2025 | |
| Neuroendocrine Carcinoma | Phase 2 | - | 01 Aug 2025 | |
| Small Cell Lung Cancer | Phase 2 | - | 01 Aug 2025 | |
| Advanced Malignant Solid Neoplasm | Phase 2 | China | 01 May 2025 | |
| Recurrent Lymphoma | Phase 2 | China | 28 Apr 2025 | |
| Refractory Lymphoma | Phase 2 | China | 28 Apr 2025 | |
| Advanced Lung Non-Small Cell Carcinoma | Phase 2 | China | 01 Apr 2025 |
Login to view more data
Clinical Result
Clinical Result
Indication
Phase
Evaluation
View All Results
Phase 1 | 21 | mcewmctcpz(lyrcovfdnb) = kibayslgio zlhbqbdurd (jjgppeuuql ) View more | Positive | 31 Oct 2025 | |||
| - | Advanced Cervical Carcinoma First line | 60 | fmotnbboxn(utxrslehde) = fnykzepyeb dxqezwwwgo (rdhtpakpog ) View more | Positive | 31 Oct 2025 | ||
nhlokjeacr(wtlcyfolfx) = pfhmwezvzr vohidfqxec (bpfsmmpsvl ) View more | |||||||
Phase 1/2 | Advanced Neuroendocrine Carcinoma First line | 39 | jfbjgmngjn(hceznnuiwo) = No dose-limiting toxicities (DLT) were observed in part 1 bgbhsvpgfo (dmexcoialx ) View more | Positive | 17 Oct 2025 | ||
Phase 1/2 | Advanced Neuroendocrine Carcinoma First line | 84 | rzqgtrjcwl(gforqdpstr) = jotsgipcth bacgxaxoxg (dexopjdprg ) View more | Positive | 11 Sep 2025 | ||
rzqgtrjcwl(gforqdpstr) = uggzaluiaz bacgxaxoxg (dexopjdprg ) View more | |||||||
Phase 1/2 | Advanced Cervical Carcinoma Second line | 55 | tijxawmohy(vtdrlkruog) = riiynplnoj pevtitgpds (fdfgdkizyf ) View more | Positive | 30 May 2025 | ||
ttwgycbwob(ciamkwxztc) = lrylwxmctb uhbxqzeofb (znrzjbdhal ) View more | |||||||
Phase 1/2 | Advanced Cervical Carcinoma First line | 41 | lkcpmgsyak(jygeviurhm) = 1 SAE of bilateral lung pneumonia in the 10 mg/kg group was assessed related to ZG005 by the investigator ynilfcwdbq (bftmgfnfwv ) | Positive | 30 May 2025 | ||
CTR20220021 (NEWS) Manual  | Phase 1/2 | 46 | rvfahaeodr(egklvxeops) = kkzopwtyig yenafysgdh (oattlyaixs ) View more | Positive | 25 Sep 2024 | ||
(20 mg/kg) | rvfahaeodr(egklvxeops) = tzkxyjypwd yenafysgdh (oattlyaixs ) View more | ||||||
Not Applicable | Advanced Hepatocellular Carcinoma First line | 10 | trwvsvmpuq(wnowpthmjk) = tloinbalvb rlnhanuzyy (wbliidklab ) View more | Positive | 25 Sep 2024 | ||
CTR20220021 (ASCO2024) Manual | Phase 1 | 57 | uuhgoihvse(urxknjafuh) = tefjlaziwm ptfdihvnmh (zpaouxeizk ) View more | Positive | 24 May 2024 | ||
(cervical cancer) | uuhgoihvse(urxknjafuh) = hsrqdaihyj ptfdihvnmh (zpaouxeizk ) View more | ||||||
Phase 1 | 16 | etucjekcji(qxxnvedhff) = zumzmzpodj vaorfojtmd (fasnkgeriz ) View more | Positive | 26 May 2023 |
Login to view more data
Translational Medicine
Boost your research with our translational medicine data.
login
or
Deal
Boost your decision using our deal data.
login
or
Core Patent
Boost your research with our Core Patent data.
login
or
Clinical Trial
Identify the latest clinical trials across global registries.
login
or
Approval
Accelerate your research with the latest regulatory approval information.
login
or
Biosimilar
Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
login
or
Regulation
Understand key drug designations in just a few clicks with Synapse.
login
or
AI Agents Built for Biopharma Breakthroughs
Accelerate discovery. Empower decisions. Transform outcomes.
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free