Last update 29 Nov 2024
ZG-005
Last update 29 Nov 2024
Overview
Basic Info
Drug Type Bispecific antibody |
Synonyms ZG-005, ZG005 |
Target |
Mechanism PD-1 inhibitors(Programmed cell death protein 1 inhibitors), TIGIT inhibitors(T cell immunoglobulin and ITIM domains inhibitors) |
Therapeutic Areas |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization- |
Drug Highest PhasePhase 2 |
First Approval Date- |
Regulation- |
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Related
11
Clinical Trials associated with ZG-005A Multicenter, Randomized, Open-label Phase II Study of ZG005 Combined With Bevacizumab Versus Sintilimab Combined With Bevacizumab for First-line Treatment of Advanced Hepatocellular Carcinoma
A Phase I/II Study to Evaluate the Safety, Pharmacokinetics, and Preliminary Efficacy of ZG005 in Combination With Etoposide and Cisplatin in Participants With Advanced Neuroendocrine Carcinoma.
ZG005联合依托泊苷及顺铂在晚期神经内分泌癌患者中的安全性、药代动力学特征及初步疗效的I/II期临床研究
[Translation] Phase I/II clinical study on the safety, pharmacokinetic characteristics and preliminary efficacy of ZG005 combined with etoposide and cisplatin in patients with advanced neuroendocrine carcinoma
100 Clinical Results associated with ZG-005
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100 Translational Medicine associated with ZG-005
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100 Patents (Medical) associated with ZG-005
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100 Deals associated with ZG-005
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R&D Status
10 top R&D records. to view more data
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Advanced Hepatocellular Carcinoma | Phase 2 | CN | 01 Sep 2024 | |
| Advanced Neuroendocrine Carcinoma | Phase 2 | CN | 24 May 2024 | |
| Advanced Cervical Carcinoma | Phase 2 | CN | 18 Mar 2024 | |
| Advanced Malignant Solid Neoplasm | Phase 2 | CN | 15 Jun 2022 | |
| Solid tumor | Phase 2 | - | - |
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Clinical Result
Clinical Result
Indication
Phase
Evaluation
View All Results
CTR20220021 (NEWS) Manual  | Phase 1/2 | 46 | gtkfofhsqy(gpnkqgjibf) = wvxshiapzq peowwxqeyb (wtcqpemwvo ) View more | Positive | 25 Sep 2024 | ||
(20 mg/kg) | gtkfofhsqy(gpnkqgjibf) = losmvzdfqt peowwxqeyb (wtcqpemwvo ) View more | ||||||
Not Applicable | Advanced Hepatocellular Carcinoma First line | 10 | rhamfwdhca(tikumvdjww) = uiocgnmrzr mbadkucmzv (zdescijeqf ) View more | Positive | 25 Sep 2024 | ||
CTR20220021 (ASCO2024) Manual | Phase 1 | 57 | crdvepgkhc(eluihpeezx) = iwgrflyhhx nmspozehcq (tegaowzfni ) View more | Positive | 24 May 2024 | ||
(cervical cancer) | crdvepgkhc(eluihpeezx) = qmiskknstp nmspozehcq (tegaowzfni ) View more | ||||||
CTR20220021 (ASCO2023) Manual | Phase 1 | 16 | flgxnqbsrx(cskpnqhmso) = kcjcnrqmij zvpacjwemp (yewopfooec ) View more | Positive | 26 May 2023 |
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