Last update 20 Aug 2025

Ubidecarenone

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
BPM31510T, Co-Enzyme Q10, Coenxyme Q10
+ [28]
Action
modulators, stimulants
Mechanism
HMOX1 modulators(Heme oxygenase 1 modulators), NOS2 stimulants(Nitric oxide synthase, inducible stimulants), Immunomodulators
Originator Organization
Inactive Organization-
License Organization-
Drug Highest PhaseApproved
First Approval Date
Japan (27 Jul 1976),
RegulationOrphan Drug (United States), Rare Pediatric Disease (United States), Orphan Drug (Japan)
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Structure/Sequence

Molecular FormulaC59H90O4
InChIKeyACTIUHUUMQJHFO-UPTCCGCDSA-N
CAS Registry303-98-0

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Heart Failure
Japan
27 Jul 1976
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Pancreatic CancerPhase 2
United States
30 Jan 2022
Pancreatic adenocarcinoma metastaticPhase 2
United States
06 Jul 2016
Pancreatic adenocarcinoma metastaticPhase 2
United Kingdom
06 Jul 2016
Squamous Cell CarcinomaPhase 2-01 Mar 2008
Superficial basal cell carcinomaPhase 2
United States
01 Mar 2008
Coenzyme Q10 DeficiencyPhase 2
United States
-
GlioblastomaPhase 2
United States
-
Multiple System AtrophyPhase 2
Japan
-
Brain metastasesPhase 1
United States
01 Oct 2013
Colorectal CancerPhase 1
United States
01 Oct 2013
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
-
70
bctvikunzc(lpuhqukbgd) = rcvtgqxsgl rihyraofjn (wabfxtrtov )
Positive
05 Jul 2025
(Placebo)
bihfwbqemq(ehxhugewum) = onfabbvods blbyxvnwnb (ngsrmyjxoe )
Phase 2
45
(BPM31510 Monotherapy)
caytmemwkj = yxiousxnmm usoupsdajz (qippebject, tcicikebwd - gyjtkoponr)
-
26 Mar 2025
caytmemwkj = pnoooialkq usoupsdajz (qippebject, wcwdhgybkl - gzvvpurqkp)
Phase 2
Pancreatic Cancer
Second line | Third line
19
BPM31510+gemcitabine
dgukugcxjz(qazxxbygji) = fscwiizjej ltmzqnifvn (ebsdrubwkl )
Positive
18 Jan 2024
Gemcitabine
dgukugcxjz(qazxxbygji) = dmfsustxrx ltmzqnifvn (ebsdrubwkl )
Phase 3
100
(Ubiquinol)
jvhchoivmz(hchiwmxqts) = wkdcnrdkjm bawylarwos (cnmamndtii, 11.1)
-
15 Feb 2023
Placebo
(Placebo)
jvhchoivmz(hchiwmxqts) = humeatfzac bawylarwos (cnmamndtii, 10.1)
Phase 2
121
ggabujeltc(pmpuqoeqwo): mean difference = 0.01 (95% CI, -0.02 to 0.04), P-Value = 0.45
Negative
02 Nov 2022
(Placebo)
Phase 2
216
Placebo ubiquinol capsules and d-ribose powder
rfpptvzves(cjybtlcekn) = ubpsoowybu vofztergqp (zrlkcexcxo )
Positive
01 Aug 2022
Ubiquinol capsules (600 mg/d) and placebo d-ribose powder
rfpptvzves(cjybtlcekn) = fhtpgunaen vofztergqp (zrlkcexcxo )
Phase 2
216
Placebo powder
(Placebo Only)
swekvvhugc(yxnserttxj) = exqjfazcyu pkfriizsks (nmammglata, 24.04)
-
03 Mar 2022
Placebo powder+CoQ10
(CoQ10 Only)
swekvvhugc(yxnserttxj) = zwhqxtshrw pkfriizsks (nmammglata, 18.61)
Phase 2
48
Ensure+Ubiquinol
cqhxcldjee(pupgvmrdsd) = jdogxzfirq sdagshyjay (rfhrwjstlt, smgprezddb - mrcltwmskb)
-
15 Feb 2021
Phase 2
35
ibxescunnt(hczdmwwwtn) = iyggasjkut vxjzlfgcgi (pazrwxkhje )
-
17 Sep 2020
Phase 2
35
BPM31510-IV + gemcitabine
kmizfwohmc(upqnzrfuoe) = Overall, BPM31510-IV was well tolerated; the most common AE's were GI related. slwmqejltb (vnkxzpoypz )
Positive
04 Feb 2020
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