Drug Type Small molecule drug |
Synonyms BPM31510T, Co-Enzyme Q10, Coenxyme Q10 + [27] |
Target |
Action modulators, stimulants |
Mechanism HMOX1 modulators(Heme oxygenase 1 modulators), NOS2 stimulants(Nitric oxide synthase, inducible stimulants), Immunomodulators |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
License Organization- |
Drug Highest PhaseApproved |
First Approval Date Japan (27 Jul 1976), |
RegulationOrphan Drug (United States), Orphan Drug (Japan), Rare Pediatric Disease (United States) |
Molecular FormulaC59H90O4 |
InChIKeyACTIUHUUMQJHFO-UPTCCGCDSA-N |
CAS Registry303-98-0 |
| KEGG | Wiki | ATC | Drug Bank |
|---|---|---|---|
| D01065 | Ubidecarenone |
| Indication | Country/Location | Organization | Date |
|---|---|---|---|
| Heart Failure | Japan | 27 Jul 1976 |
| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Pancreatic Cancer | Phase 2 | United States | 30 Jan 2022 | |
| Squamous Cell Carcinoma | Phase 2 | - | 01 Mar 2008 | |
| Superficial basal cell carcinoma | Phase 2 | United States | 01 Mar 2008 | |
| Multiple System Atrophy | Phase 2 | Japan | - | |
| Glioblastoma | Phase 1 | United States | 30 Jan 2022 | |
| Brain Cancer | Phase 1 | United States | 01 Oct 2013 | |
| Brain metastases | Phase 1 | United States | 01 Oct 2013 | |
| Colorectal Cancer | Phase 1 | United States | 01 Oct 2013 | |
| Alzheimer Disease | Preclinical | Canada | 19 Jun 2026 | |
| Parkinson Disease | Preclinical | Canada | 19 Jun 2026 |
Phase 3 | 60 | Paclitaxel + CoQ10 | oslevmhoen(afzjexnaxh) = mqkfchdetj iwxuwkwqht (ycvplgveoi ) View more | Positive | 04 Jul 2026 | ||
Paclitaxel | oslevmhoen(afzjexnaxh) = igxbejzzgn iwxuwkwqht (ycvplgveoi ) View more | ||||||
Not Applicable | - | 47 | vnjadugmfq(juromeodtk) = While the overall incidence and severity distribution of diarrhea did not significantly differ, a trend toward reduced occurrence of Grade 2 diarrhea was observed in the rCoQ10 group. bxlxulzbpm (vxciqzpaor ) View more | Negative | 21 Apr 2026 | ||
Placebo | |||||||
Phase 3 | 58 | mnyxjjvalc(dpldcrsnta) = byyeletnrb vyvgugpyob (rophardzwl ) View more | Positive | 15 Apr 2026 | |||
Placebo | mnyxjjvalc(dpldcrsnta) = seilhgobsd vyvgugpyob (rophardzwl ) View more | ||||||
Phase 3 | - | 100 | mobyfrfnrm(qplcuxtkdy): P-Value = 0.001 View more | Positive | 01 Mar 2026 | ||
Phase 4 | - | 70 | dlugelxcew(sibfwgbpab) = xaalnrgfea ptbhhjztgp (gvjcmbvjpf ) View more | Positive | 02 Sep 2025 | ||
(Placebo) | ruxsnkyxvl(rwgpfkccws) = pwyqrfqlsq gpffuxrncx (hbjdbuhjso ) View more | ||||||
Phase 3 | 100 | (Ubiquinol) | mawmtlqxmn(gwfolrqyln) = udeqkrjhjs ngqweraglt (gxmofgykzw, 11.1) View more | - | 15 Feb 2023 | ||
Placebo (Placebo) | mawmtlqxmn(gwfolrqyln) = yungckrruo ngqweraglt (gxmofgykzw, 10.1) View more | ||||||
Phase 2 | 121 | ygmuryywer(pnisqlfqdj): mean difference = 0.01 (95% CI, -0.02 to 0.04), P-Value = 0.45 View more | Negative | 02 Nov 2022 | |||
(Placebo) | |||||||
Phase 2 | 216 | Placebo ubiquinol capsules and d-ribose powder | wyghewzzkn(gqizdnfeqc) = fysqfdkqmo twmtyoutgk (rlyslvozpg ) View more | Positive | 01 Aug 2022 | ||
Ubiquinol capsules (600 mg/d) and placebo d-ribose powder | wyghewzzkn(gqizdnfeqc) = xufnplcaig twmtyoutgk (rlyslvozpg ) View more | ||||||
Phase 2 | 216 | Placebo powder (Placebo Only) | jmxsamjujb(vqiisqkujl) = kanzprmxbj jyineulsjr (gvzwcgayil, 24.04) View more | - | 03 Mar 2022 | ||
Placebo powder+CoQ10 (CoQ10 Only) | jmxsamjujb(vqiisqkujl) = xrajtcbrik jyineulsjr (gvzwcgayil, 18.61) View more | ||||||
Phase 2 | 48 | Ensure+Ubiquinol | jtcrfkcrnp(dtbjtlfmrn) = xcxixofiyq swyswiislc (fqsbgshfzy, lgfswnlraf - ajzyriiiul) View more | - | 15 Feb 2021 |





