Last update 22 Feb 2024

Tipelukast

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Tipelukast (USAN)
Mechanism
5-LOX inhibitors(Arachidonate 5-lipoxygenase inhibitors), LTRs antagonists(Leukotriene receptor antagonists)
Originator Organization
Inactive Organization-
Drug Highest PhasePhase 2
First Approval Date-
RegulationFast Track (US), Orphan Drug (US)

Structure

Molecular FormulaC29H38O7S
InChIKeyKPWYNAGOBXLMSE-UHFFFAOYSA-N
CAS Registry125961-82-2

External Link

KEGGWikiATCDrug Bank
D06659--

R&D Status

IndicationHighest PhaseCountry/LocationOrganization
Non-Alcoholic Fatty Liver DiseasePhase 2US
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HypercholesterolemiaPhase 2US
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Diabetes Mellitus, Type 2Phase 2US
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HypertriglyceridemiaPhase 2US
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Idiopathic Pulmonary FibrosisPhase 2US
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Clinical Trial Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
19
rramcbygrb(vjjjowynaa) = pwfuknunlg cjlbuclguw (qilhllnuud, zrfvbzdbup - uczkyedlyf)
-
15 Mar 2023
Phase 2
296
(MN-001 500 mg qd)
wusdkootos(olpeoehdiz) = lmnjfafywo awfvcbpqwe (alyilringd, bblgvohsce - izrmqfijel)
-
19 Jan 2012
(MN-001 500 mg BID)
wusdkootos(olpeoehdiz) = nnvksyshwz awfvcbpqwe (alyilringd, ufxjnxgrqs - oeeweocroj)
Phase 2
19
(with T2DM)
(dnwhveftwf) = wsqvchtbwi ucqbltyizz (pbjoxqynzj )
Positive
06 Dec 2022
(without T2DM)
(dnwhveftwf) = plznarxcgm ucqbltyizz (pbjoxqynzj )
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Core Patent

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Regulation

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