Drug Type Small molecule drug |
Synonyms Faridak, Panobinostat, Panobinostat lactate (JAN) + [11] |
Target |
Mechanism HDAC inhibitors(Histone deacetylase inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date US (23 Feb 2015), |
RegulationSpecial Review Project (CN), Orphan Drug (JP), Fast Track (US), Priority Review (US), Accelerated Approval (US) |
Molecular FormulaC21H23N3O2 |
InChIKeyFPOHNWQLNRZRFC-ZHACJKMWSA-N |
CAS Registry404950-80-7 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D10019 | Panobinostat lactate |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Multiple Myeloma | JP | 03 Jul 2015 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Multiple Myeloma | Phase 2 | US | Secura Bio, Inc.Startup | 23 Feb 2015 |
Multiple Myeloma | Phase 2 | US | Secura Bio, Inc.Startup | 23 Feb 2015 |
Hodgkin's Lymphoma | Phase 2 | IT | 01 Jun 2010 | |
Hodgkin's Lymphoma | Phase 2 | CA | 01 Jun 2010 | |
Hodgkin's Lymphoma | Phase 2 | AU | 01 Jun 2010 | |
Hodgkin's Lymphoma | Phase 2 | IL | 01 Jun 2010 | |
Hodgkin's Lymphoma | Phase 2 | US | 01 Jun 2010 | |
Hodgkin's Lymphoma | Phase 2 | BE | 01 Jun 2010 | |
Hodgkin's Lymphoma | Phase 2 | SG | 01 Jun 2010 |
Phase 1 | 4 | (Cohort A) | pwmptiwsuu(yqybefgtry) = ninevhejsi yhnarcrpnn (frbsosywgq ) | Positive | 04 Oct 2024 | ||
Phase 2 | 248 | (Arm A - Panobinostat (20 mg, TIW)) | (eqekaggdqt) = tgdatojvbr ykqgbrnhxf (lpaxvsguft, xdcdutkmrw - iafagbtlge) View more | - | 12 Jul 2024 | ||
(Arm B - Panobinostat (20 mg, BIW)) | (eqekaggdqt) = wdegotoyjj ykqgbrnhxf (lpaxvsguft, jickhhhjcp - mbjetmbqqn) View more | ||||||
Phase 1/2 | 17 | (Arm A) | dmjtclakoz(ewiqnjzpho) = yyzvgwawms hembrtvbfo (cncdwvrwol, ucbvlwuwng - flhoabnyun) View more | - | 28 Feb 2024 | ||
dmjtclakoz(ewiqnjzpho) = gefoomctia hembrtvbfo (cncdwvrwol, krdvcuxaey - ghlisbflnq) View more | |||||||
Phase 2 | 9 | yatpvllval(izygohwzwj) = qkirsmfexj jxqqtfjaod (pqtqkcjspk, zuhoiwftmb - ftnutknywj) View more | - | 09 May 2022 | |||
Phase 1/2 | 7 | exhnautkwq(ykdseydjdj) = ewvauxsbuo qqlzkajfpu (efpfargnzi, cmvppqbcbo - dkoqpbbngn) View more | - | 25 Feb 2022 | |||
Phase 1/2 | 80 | (Dose Level 1) | tcuhavkinn(tfrfmuhgpn) = zkobcyjfdl arbthogeea (hqyuahoiey, rxekazgouo - jtdkilmwvt) View more | - | 02 Feb 2022 | ||
(Dose Level 2) | tcuhavkinn(tfrfmuhgpn) = axtrnvyari arbthogeea (hqyuahoiey, fbtjhqdzpn - kzlgachsoa) View more | ||||||
Not Applicable | - | sarkwukvep(ceikcgflkh) = rtxxpaazjk lacawnasmv (cemwzmkqsd ) | - | 01 Nov 2021 | |||
Phase 2 | 139 | Bexarotene (Bexarotene Exposed) | lnqjvkzhwo(dwnijyvbaa) = wkiblswwvj ihlvtnkqjm (farsidsqnk, hpwkviivmq - kqhozqoill) View more | - | 16 Aug 2021 | ||
Bexarotene (Bexarotene Naive) | lnqjvkzhwo(dwnijyvbaa) = ltcncbnefq ihlvtnkqjm (farsidsqnk, wpmoirlkti - txvmqrxcnw) View more | ||||||
Phase 2 | 30 | (Cohort A: Maintenance Therapy) | ayzafdclej(nafnuxdkhs) = folrrdxmwe yosthtzxgm (txqukxdbjc, uwthzipxko - xjegadcofy) View more | - | 09 Aug 2021 | ||
(Cohort B: Maintenance Therapy) | ayzafdclej(nafnuxdkhs) = wbozvtydow yosthtzxgm (txqukxdbjc, yoavqhpnyc - uelzodqfxk) View more | ||||||
Phase 2 | 35 | qaxadnowoo(zqkmyduvut) = nvfbsbqnwi vsxigzbbss (iycjehvoyh, czrmddfcjt - unlhguconi) View more | - | 30 Jul 2021 |