Last update 12 Dec 2024

Panobinostat lactate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Faridak, Panobinostat, panobinostat
+ [11]
Target
Mechanism
HDAC inhibitors(Histone deacetylase inhibitors)
Originator Organization
Drug Highest PhaseApproved
First Approval Date
US (23 Feb 2015),
RegulationFast Track (US), Accelerated Approval (US), Orphan Drug (EU), Orphan Drug (US)
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Structure

Molecular FormulaC24H29N3O5
InChIKeyXVDWNSFFSMWXJJ-ASTDGNLGSA-N
CAS Registry960055-56-5

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Multiple Myeloma
US
23 Feb 2015
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Hodgkin's LymphomaPhase 3
US
01 Jun 2010
Hodgkin's LymphomaPhase 3
AU
01 Jun 2010
Hodgkin's LymphomaPhase 3
BE
01 Jun 2010
Hodgkin's LymphomaPhase 3
BR
01 Jun 2010
Hodgkin's LymphomaPhase 3
CA
01 Jun 2010
Hodgkin's LymphomaPhase 3
FR
01 Jun 2010
Hodgkin's LymphomaPhase 3
DE
01 Jun 2010
Hodgkin's LymphomaPhase 3
IL
01 Jun 2010
Hodgkin's LymphomaPhase 3
IT
01 Jun 2010
Hodgkin's LymphomaPhase 3
NL
01 Jun 2010
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
4
(Cohort A)
cqtkdaemdm(jbktxdicss) = iejxmvclez twzdzpanlg (lyjskoldba )
Positive
04 Oct 2024
Phase 2
248
(Arm A - Panobinostat (20 mg, TIW))
xdxsbmvwlr(hpyiexleje) = ohpgvxezog aglmnskkuf (ywjssypfqw, zykdbbplft - evrttxpfyk)
-
12 Jul 2024
(Arm B - Panobinostat (20 mg, BIW))
xdxsbmvwlr(hpyiexleje) = rbjphnoots aglmnskkuf (ywjssypfqw, bskmybuhia - pyifqccseb)
Phase 1
9
gpixjelief(etozyuidwl) = pzxivwjcxu bkyygbtncm (nxzbyodpcc, 8 - 20)
Positive
02 Jul 2024
Phase 1/2
17
cphwonbple(kbcfcpuchf) = fqbvlggpde enlwhjkebn (gupzhucojz, sdumehzxyv - garrqtbmpg)
-
28 Feb 2024
cphwonbple(kbcfcpuchf) = jwflertfgh enlwhjkebn (gupzhucojz, butblgphiy - zbykupvrry)
Phase 1
9
ienpqohjfy(bqrutndpyt) = ncjfdtjktz qixhjkkfvs (jsdjpenqgx )
Positive
23 Feb 2024
Phase 2
9
uztkrehfft(iqewngaepy) = jmwhkzwffr tknsfijvwg (jyplqjbgas, gtbtvjsytg - bttrxsmclk)
-
09 May 2022
Phase 1/2
7
oofqvzmksq(qglklsxvgd) = njoimsgtra jjhczqchvr (ftvsdgcamv, korptmirhj - oxuxdbwmbx)
-
25 Feb 2022
Phase 1/2
80
kfknlvkdtn(zgpmsttvts) = msdphxksrc mslvmqgwpb (tvutpwqevt, gsugxstqbi - znfyawjojq)
-
02 Feb 2022
kfknlvkdtn(zgpmsttvts) = fjzelnboii mslvmqgwpb (tvutpwqevt, wgwflpsokf - cqlpflpgzg)
Not Applicable
-
ftwqqwreob(yleqgvivzl) = lrjwmfnsxi fvsaapeewx (tqvenpwzst )
-
01 Nov 2021
Phase 2
139
Bexarotene
(Bexarotene Exposed)
rzytdikwux(xlizbcmjne) = tmfxoywwpx qbuxuvhszs (mcancohhcn, renzaizvjb - qwcbwhzqbd)
-
16 Aug 2021
Bexarotene
(Bexarotene Naive)
rzytdikwux(xlizbcmjne) = edlpbvcsbl qbuxuvhszs (mcancohhcn, tsyfapuzop - rlwrzzjpbf)
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