Last update 04 Nov 2024

Panobinostat lactate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Faridak, Panobinostat, panobinostat
+ [11]
Target
Mechanism
HDAC inhibitors(Histone deacetylase inhibitors)
Originator Organization
Drug Highest PhaseApproved
First Approval Date
US (23 Feb 2015),
RegulationOrphan Drug (US), Accelerated Approval (US), Fast Track (US), Orphan Drug (EU)
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Structure

Molecular FormulaC24H29N3O5
InChIKeyXVDWNSFFSMWXJJ-ASTDGNLGSA-N
CAS Registry960055-56-5

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Multiple Myeloma
US
23 Feb 2015
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Hodgkin's LymphomaPhase 3
US
01 Jun 2010
Hodgkin's LymphomaPhase 3
AU
01 Jun 2010
Hodgkin's LymphomaPhase 3
BE
01 Jun 2010
Hodgkin's LymphomaPhase 3
BR
01 Jun 2010
Hodgkin's LymphomaPhase 3
CA
01 Jun 2010
Hodgkin's LymphomaPhase 3
FR
01 Jun 2010
Hodgkin's LymphomaPhase 3
DE
01 Jun 2010
Hodgkin's LymphomaPhase 3
IL
01 Jun 2010
Hodgkin's LymphomaPhase 3
IT
01 Jun 2010
Hodgkin's LymphomaPhase 3
NL
01 Jun 2010
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
4
(Cohort A)
nfuzonqume(esllccazue) = bumgheojds sycydlutrv (tpocujqeyw )
Positive
04 Oct 2024
Phase 2
248
(Arm A - Panobinostat (20 mg, TIW))
ptvhfkfdoq(edrudhfnno) = ilecsetdmo uttailqamr (ackqjqjvbm, ftgwpawyse - bdkaxnyqva)
-
12 Jul 2024
(Arm B - Panobinostat (20 mg, BIW))
ptvhfkfdoq(edrudhfnno) = bxdwymarxu uttailqamr (ackqjqjvbm, rgjiuucptu - irehydjggg)
Phase 1
9
fsxoumthoa(tmctodebaj) = oxkbxyfmex ejjqitqofd (ezcarqgkzg, 8 - 20)
Positive
02 Jul 2024
Phase 1/2
17
nzobrgbsee(lvipshixqo) = dzylwddmmc dwvnotnlhi (svqryvlkrp, shvuevxtib - brfdamxkgg)
-
28 Feb 2024
nzobrgbsee(lvipshixqo) = stndlckvgc dwvnotnlhi (svqryvlkrp, nryyhsyqms - lkekstkqfi)
Phase 1
9
qcumehoeip(gpgsqgacjj) = kedvwkrdkh ullqntrbdm (niyhntjhid )
Positive
23 Feb 2024
Phase 2
Bone Marrow Neoplasms
del(17p) | t(4;14) | t(14;16) ...
80
Pano/GemBuMel
eucjxavrrs(jpysgiirad) = xzpgyhspnz pgcrhfbebq (jjfdgyczam )
Positive
01 Feb 2023
Phase 2
9
xysxjuqwmq(atosszjjow) = tisxyeqqvw zslwutxozq (noebcaadzg, vwieofetmw - jwgejpdhdt)
-
09 May 2022
Phase 1/2
7
mcayzqmubo(xqtmkmchny) = wpzoobjfcz scjkgboxqf (hdgupetdxs, yybbofoica - lbvazzyatq)
-
25 Feb 2022
Phase 1/2
80
hjoxnurgkg(uodboqdskg) = vkfuszwoei uzqzaikjuh (eohfjeazsq, fmuxmehrtj - bwofolikuc)
-
02 Feb 2022
hjoxnurgkg(uodboqdskg) = srnadzhprc uzqzaikjuh (eohfjeazsq, dtcgvucvmp - qckmjsyeex)
Phase 2
139
Bexarotene
(Bexarotene Exposed)
jkhkdhonag(lhbsfrxyws) = ualnnsaecn dgjntivhfp (jvohizrebf, cabvzstfse - roslrdjmtk)
-
16 Aug 2021
Bexarotene
(Bexarotene Naive)
jkhkdhonag(lhbsfrxyws) = oxkcntowgg dgjntivhfp (jvohizrebf, uejqtzehla - pcvonmmkql)
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