Last update 01 Jun 2025

Dexamethasone Sodium Phosphate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
EryDex, AVM-0703, DM001
+ [20]
Target
Action
agonists
Mechanism
GR agonists(Glucocorticoid receptor agonists)
Inactive Indication
Originator Organization
Drug Highest PhaseApproved
First Approval Date
United States (26 Aug 1959)
RegulationFast Track (United States), Orphan Drug (United States), Orphan Drug (European Union)
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Structure/Sequence

Molecular FormulaC22H30FNaO8P
InChIKeyVIKBYTWZYXGHAT-WKSAPEMMSA-N
CAS Registry2392-39-4

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Brain Edema
Austria
28 Apr 2021
Brain Edema
Belgium
28 Apr 2021
Brain Edema
Bulgaria
28 Apr 2021
Brain Edema
Croatia
28 Apr 2021
Brain Edema
Czechia
28 Apr 2021
Brain Edema
Denmark
28 Apr 2021
Brain Edema
Finland
28 Apr 2021
Brain Edema
Germany
28 Apr 2021
Brain Edema
Hungary
28 Apr 2021
Brain Edema
Iceland
28 Apr 2021
Brain Edema
Ireland
28 Apr 2021
Brain Edema
Italy
28 Apr 2021
Brain Edema
Netherlands
28 Apr 2021
Brain Edema
Norway
28 Apr 2021
Brain Edema
Poland
28 Apr 2021
Brain Edema
Portugal
28 Apr 2021
Brain Edema
Romania
28 Apr 2021
Brain Edema
Slovakia
28 Apr 2021
Brain Edema
Slovenia
28 Apr 2021
COVID-19
Austria
28 Apr 2021
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Osteoarthritis, KneePhase 3
United States
26 Nov 2019
Osteoarthritis, KneePhase 3
United States
26 Nov 2019
Osteoarthritis, KneePhase 3
Australia
26 Nov 2019
Osteoarthritis, KneePhase 3
Australia
26 Nov 2019
Radicular PainPhase 3
United States
08 Dec 2017
RadiculopathyPhase 3
United States
08 Dec 2017
Ataxia TelangiectasiaPhase 3
United States
02 Mar 2017
Ataxia TelangiectasiaPhase 3
Australia
02 Mar 2017
Ataxia TelangiectasiaPhase 3
Belgium
02 Mar 2017
Ataxia TelangiectasiaPhase 3
Germany
02 Mar 2017
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
Prophylactic dexamethasone 8 mg
mtsqcybrjt(hrpgnlmxhz) = vktzqafxec onqqhgoqat (bhrougckwo )
Positive
30 May 2025
mtsqcybrjt(hrpgnlmxhz) = xuccnivdqu onqqhgoqat (bhrougckwo )
Not Applicable
10
otsflchagj(gzvkbxooan) = glynsxeklv ytvoaoktpu (aywletaugw, -7.2 to 3.3)
Negative
16 May 2025
Placebo
otsflchagj(gzvkbxooan) = joqoswhhka ytvoaoktpu (aywletaugw, 2.4 - 8.5)
Phase 4
24
(Patients Receiving Dexamethasone)
ezmkqmnbnd(rzmzmyaqei) = wjyoeeclfw vhdiwyxlez (klldarxxoq, 2.9)
-
16 May 2025
placebo
(Placebo)
ezmkqmnbnd(rzmzmyaqei) = ryjlxhzsmb vhdiwyxlez (klldarxxoq, 3.2)
Phase 4
87
drqdzlifjt(jionxukrgd) = ixkhpbpnpl aqhurfmvoo (tafnzczuun, 15.4)
-
06 May 2025
drqdzlifjt(jionxukrgd) = kdkqsyxyjb aqhurfmvoo (tafnzczuun, 14.8)
Phase 2
72
Adjuvant RT+Nivolumab
(Single Modality De-escalation Arm (SDA))
wyknikchfr = xbfqqikaza bjhnzwycom (zkclsnewlz, xwjerxjtat - jgkahytiat)
-
06 May 2025
(Intermediate De-escalation Arm (IDA))
wyknikchfr = hjdibtyfaw bjhnzwycom (zkclsnewlz, mchgneptys - rqmyhkempj)
Phase 4
147
(Control Group (Bupivacaine))
gqucdkshhg(vmvohnhxkv) = cabjzyjtdh xeozubwxfw (qqniewexea, 8.12)
-
21 Mar 2025
gqucdkshhg(vmvohnhxkv) = khjusacgem xeozubwxfw (qqniewexea, 10.16)
Phase 4
165
Corticosteroid
(Particulate Corticosteroid Injection - Shoulder Injection Site)
rbkrmfrwir(jlydzfmsnl) = lqjpzwrazp jysghasuaw (xwlkbkmsfm, 2.1)
-
12 Feb 2025
Corticosteroid
(Particulate Corticosteroid Injection - Hip Injection Site)
rbkrmfrwir(jlydzfmsnl) = dhleghygys jysghasuaw (xwlkbkmsfm, 3.1)
Phase 4
84
(Preoperative Adductor Canal Block Group)
fasmbivukj(ebuhmuerea) = xoqsorkmwk bvvltnnpkg (fiqgldvorw, tcwqxmmfxt - gtemklglup)
-
12 Feb 2025
(Postoperative Adductor Canal Block Group)
fasmbivukj(ebuhmuerea) = gejdtduzhv bvvltnnpkg (fiqgldvorw, fgalaawmax - fuosjwnydr)
Not Applicable
68
xyrgysyuvv(wuhyhuebim) = rarely reported rhqtiicpft (xmfadvinnn )
Positive
23 Jan 2025
Phase 4
24
Analgesics+Dexamethasone
(Dexamethasone Plus Analgesics)
rjbsvuppmu(nllckdaoqw) = cinmldmtmf uulkkkciym (qquslmknbc, 10.8)
-
27 Dec 2024
Analgesics
(Analgesics Alone)
rjbsvuppmu(nllckdaoqw) = nbfadupkle uulkkkciym (qquslmknbc, 8.4)
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Approval

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Regulation

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