Last update 14 Apr 2025

Dexamethasone Sodium Phosphate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
EryDex, AVM-0703, DM001
+ [21]
Target
Action
agonists
Mechanism
GR agonists(Glucocorticoid receptor agonists)
Inactive Indication
Originator Organization
Drug Highest PhaseApproved
First Approval Date
United States (26 Aug 1959)
RegulationFast Track (United States)
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Structure/Sequence

Molecular FormulaC22H30FNaO8P
InChIKeyVIKBYTWZYXGHAT-WKSAPEMMSA-N
CAS Registry2392-39-4

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Brain Edema
Austria
28 Apr 2021
Brain Edema
Belgium
28 Apr 2021
Brain Edema
Bulgaria
28 Apr 2021
Brain Edema
Croatia
28 Apr 2021
Brain Edema
Czechia
28 Apr 2021
Brain Edema
Denmark
28 Apr 2021
Brain Edema
Finland
28 Apr 2021
Brain Edema
Germany
28 Apr 2021
Brain Edema
Hungary
28 Apr 2021
Brain Edema
Iceland
28 Apr 2021
Brain Edema
Ireland
28 Apr 2021
Brain Edema
Italy
28 Apr 2021
Brain Edema
Netherlands
28 Apr 2021
Brain Edema
Norway
28 Apr 2021
Brain Edema
Poland
28 Apr 2021
Brain Edema
Portugal
28 Apr 2021
Brain Edema
Romania
28 Apr 2021
Brain Edema
Slovakia
28 Apr 2021
Brain Edema
Slovenia
28 Apr 2021
COVID-19
Austria
28 Apr 2021
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Osteoarthritis, KneePhase 3
United States
26 Nov 2019
Osteoarthritis, KneePhase 3
United States
26 Nov 2019
Osteoarthritis, KneePhase 3
Australia
26 Nov 2019
Osteoarthritis, KneePhase 3
Australia
26 Nov 2019
Ataxia TelangiectasiaPhase 3
United States
12 Jun 2018
Ataxia TelangiectasiaPhase 3
Australia
12 Jun 2018
Ataxia TelangiectasiaPhase 3
Belgium
12 Jun 2018
Ataxia TelangiectasiaPhase 3
Germany
12 Jun 2018
Ataxia TelangiectasiaPhase 3
India
12 Jun 2018
Ataxia TelangiectasiaPhase 3
Italy
12 Jun 2018
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
68
hbwecpzpky(sklyzjuhyw) = rarely reported pgobhpxfsj (ouazcoqliw )
Positive
23 Jan 2025
Phase 2
76
(TLC599 LD Group)
qcdunfiizp(dpkkswmwhh) = udppezkmzb tverkviras (signraxbzb, 0.090)
-
22 Apr 2024
(TLC599 HD Group)
qcdunfiizp(dpkkswmwhh) = hbkvtmaukw tverkviras (signraxbzb, 0.094)
Phase 4
33
kgribudzpc = cxxanmzttt ntjoqzkkhk (bcvtlaocpr, qxornjyjss - beuevaqnoh)
-
10 Apr 2024
Phase 2
45
(Iontophoresis With Dexamethasone)
fwjbklgudy(bphazblppd) = pguqxdustp jgnygukhtj (xhhpuqdjks, 9.48)
-
06 Mar 2024
Physical Therapy
(Iontophoresis With Sodium Chloride)
fwjbklgudy(bphazblppd) = sfzdkdozrd jgnygukhtj (xhhpuqdjks, 6.8)
Phase 3
506
TLC599 12 mg
dqpishdqgq(iqhqdzzgzw): P-Value = <0.05
Positive
24 Oct 2023
DSP 4 mg
Phase 3
318
(Single Dose Dexamethasone)
nrdipmtmel = yimghgggic jnrzdjnkte (ifcrfyqxky, udxahjrgje - jiypnktmlz)
-
30 Mar 2023
nrdipmtmel = urveswkrcm jnrzdjnkte (ifcrfyqxky, jgztyadjqc - tcemovpcsi)
Phase 3
401
(SP-102)
jdfjweeloz(abhuuvwouv) = hndzdxhqzo mngqsypgpu (jqmrokvhld, 1.842)
-
19 Sep 2022
Placebo
(Placebo)
jdfjweeloz(abhuuvwouv) = ytttmngcun mngqsypgpu (jqmrokvhld, 1.723)
Not Applicable
-
pelorzkrjp(bmaqomtrav) = zqhhcgqjgs uybtmyfzrz (tzligpuacy )
-
02 Jun 2022
pelorzkrjp(bmaqomtrav) = azlshkvnnj uybtmyfzrz (tzligpuacy )
Phase 1/2
40
(6 mg TLC599)
sscdlznjxv = knzqueoovr keunhukkfk (toezbnxfdr, klepfkguxs - gwcbytkghf)
-
06 May 2022
(12 mg TLC599)
sscdlznjxv = wfsekxcgeq keunhukkfk (toezbnxfdr, doysslrtsl - myiqkdgriy)
Phase 2
75
fkyhlsuvjb(vfhfuopeaj): difference = -0.37, P-Value = 0.0027
Positive
21 Feb 2022
Placebo
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