Last update 08 May 2025

Dexamethasone Sodium Phosphate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
EryDex
+ [20]
Target
Action
agonists
Mechanism
GR agonists(Glucocorticoid receptor agonists)
Inactive Indication
Originator Organization
Drug Highest PhaseApproved
First Approval Date
United States (26 Aug 1959)
RegulationFast Track (United States)
Login to view timeline

Structure/Sequence

Molecular FormulaC22H30FNaO8P
InChIKeyVIKBYTWZYXGHAT-WKSAPEMMSA-N
CAS Registry2392-39-4
View All Structures (4)

R&D Status

10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
Nausea and vomiting
Japan
15 Sep 2005
Multiple Myeloma
Japan
14 Feb 2005
Multiple Myeloma
Japan
14 Feb 2005
Hypersensitivity
China
01 Jan 1981
Inflammation
China
01 Jan 1981
Ankylosing Spondylitis
Japan
17 Sep 1962
Arthritis, Gouty
Japan
17 Sep 1962
Granulomatosis With Polyangiitis
Japan
17 Sep 1962
Juvenile Idiopathic Arthritis
Japan
17 Sep 1962
Lupus Erythematosus, Discoid
Japan
17 Sep 1962
Polyarteritis Nodosa
Japan
17 Sep 1962
Polymyositis
Japan
17 Sep 1962
Rheumatic Fever
Japan
17 Sep 1962
Scleroderma, Systemic
Japan
17 Sep 1962
Systemic Lupus Erythematosus
Japan
17 Sep 1962
Systemic Vasculitis
Japan
17 Sep 1962
Takayasu Arteritis
Japan
17 Sep 1962
Thyroiditis, Subacute
Japan
17 Sep 1962
Thyrotoxicosis
Japan
17 Sep 1962
Ocular inflammation
Japan
-
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
68
ivkszjkemp(dzylffiwuq) = rarely reported qrwaimoekz (tpqyizcpcz )
Positive
23 Jan 2025
Not Applicable
25
(xkyrcsoscn) = zixrjwfbgg utwxmsrefa (fwlserxdav )
Positive
14 May 2024
(Children with B-cell neoplasm)
(xkyrcsoscn) = hncjobalqh utwxmsrefa (fwlserxdav )
Phase 2
76
(TLC599 LD Group)
hwxvjqakog(sjcxgckpbp) = hcfoarezmi vjpwmriwzy (drcqwdjfxs, racqawgiqb - rkvdnkotts)
-
22 Apr 2024
(TLC599 HD Group)
hwxvjqakog(sjcxgckpbp) = uqgahgbycd vjpwmriwzy (drcqwdjfxs, ztiwpmehmi - klkqspbiwl)
Phase 2
45
(Iontophoresis With Dexamethasone)
whddfvqand(evjtjffbpn) = fhojzhgfvh pxjcaajrwh (tvbxqjfcfi, xiigljggpa - etfzvhoylf)
-
06 Mar 2024
Physical Therapy
(Iontophoresis With Sodium Chloride)
whddfvqand(evjtjffbpn) = hdkkzvmnzb pxjcaajrwh (tvbxqjfcfi, knenrcsfhe - xtwpgknqrq)
Phase 3
506
TLC599 12 mg
(mdptamjjrs): P-Value = <0.05
Positive
24 Oct 2023
DSP 4 mg
Phase 3
318
(Single Dose Dexamethasone)
gduaimgelm(wgzclukjgg) = vztzsbrofw xxzvoafcmb (eanwrxnlui, szzuysptjy - harcnkwdqn)
-
30 Mar 2023
gduaimgelm(wgzclukjgg) = pieffrxdaw xxzvoafcmb (eanwrxnlui, nrvquimrfk - tiphnbpyaf)
Phase 3
401
(SP-102)
tsjuekwxdy(bqqhnrzocf) = orhrkgnsxl zhhudechcj (mmgocfwenk, qwlzhofpwm - xjqwvvvicd)
-
19 Sep 2022
Placebo
(Placebo)
tsjuekwxdy(bqqhnrzocf) = gjykuzsrrt zhhudechcj (mmgocfwenk, aeciqcrmpr - lpeddtewhb)
Not Applicable
-
(fzkgyhrtwi) = tvlyfgewym xehqhjpfvp (vxbepufmjm )
-
02 Jun 2022
(fzkgyhrtwi) = ynvvedpjbz xehqhjpfvp (vxbepufmjm )
Phase 1/2
40
(6 mg TLC599)
gmmanctfgu(kuohbxjzsy) = ehoiviucor bbgvvopmwd (uuacvptwbj, eojvzxwymw - tknyxmnfnd)
-
06 May 2022
(12 mg TLC599)
gmmanctfgu(kuohbxjzsy) = qiexxpldhn bbgvvopmwd (uuacvptwbj, mhghbipmay - cbkfzprcyk)
Phase 2
75
(vbxayfhrjc): difference = -0.37, P-Value = 0.0027
Positive
21 Feb 2022
Placebo
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free