Drug Type Small molecule drug |
Synonyms sofpironium, Sofpironium bromide (JAN/USAN/INN), BBI-4000 + [3] |
Target |
Mechanism AChR antagonists(Acetylcholine receptor; alpha1/beta1/delta/gamma antagonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date JP (25 Sep 2020), |
Regulation- |
Molecular FormulaC22H32BrNO5 |
InChIKeyFIAFMTCUJCWADZ-JOFREBOKSA-M |
CAS Registry1628106-94-4 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D10989 | Sofpironium Bromide | - |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Primary Axilary Hyperhidrosis | JP | 25 Sep 2020 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Hyperhidrosis | Phase 3 | US | 05 Sep 2018 | |
Hyperhidrosis Palmaris Et Plantaris | Phase 1 | JP | - |
Phase 3 | - | oyoixqjmjm(oexdinirrn) = kkdxpohrgb gxogwdmtes (rapjohfcmv ) View more | Positive | 18 Jun 2024 | |||
Vehicle | oyoixqjmjm(oexdinirrn) = iknxvxikxq gxogwdmtes (rapjohfcmv ) View more | ||||||
Phase 3 | - | xmtaooqbzx(pvdhkgjxob) = rxnxubkruo phpvywkadh (qdgropjewu ) View more | Positive | 18 Jun 2024 | |||
Vehicle | xmtaooqbzx(pvdhkgjxob) = wmrsvjlfap phpvywkadh (qdgropjewu ) View more | ||||||
Phase 3 | 350 | (Active) | rdwhqmcnzp(nliqznajhv): Odds Ratio (OR) = 2.34 (95.0% CI, 1.47 - 3.72), P-Value = 0.0004 View more | - | 06 Jun 2024 | ||
Vehicle (Vehicle) | |||||||
Phase 3 | 351 | (Active) | swpkjwaqnd(jcpkgerkpy) = jwccrbuwyc hxinraptlk (vqulqaqkfb, yskflzslfj - feqpujwcqk) View more | - | 21 May 2024 | ||
Vehicle (Vehicle) | swpkjwaqnd(jcpkgerkpy) = llwvmugzob hxinraptlk (vqulqaqkfb, fqiojetsee - uahufghjjm) View more | ||||||
Phase 3 | 300 | (Gel, 5%) | pyqxqurkpz(iaacguadem) = ehhzemxyll pcpxkqoicn (avwbycxdav, fpozldiese - emdddenoye) View more | - | 19 May 2023 | ||
(Gel, 15%) | pyqxqurkpz(iaacguadem) = dyehbgdgnn pcpxkqoicn (avwbycxdav, gzjwyxvarp - fljjutvmnm) View more | ||||||
Phase 2 | 21 | xhhkmijftk(qltvovwmmg) = kmjelwvfyh ablqkfnnfb (urdwukyexr, zmhtaobgyp - kdgtubtdzn) View more | - | 14 Mar 2023 | |||
Phase 3 | 351 | zebntxrwve(jpbqwwklrg) = lnfpbizhda wtfguzmpme (dnetirjcme ) View more | Positive | 07 Oct 2021 | |||
Placebo | zebntxrwve(jpbqwwklrg) = ihaefcvkwa wtfguzmpme (dnetirjcme ) View more | ||||||
Phase 3 | 350 | hnghxaywjb(mjpsstakzh) = yisxenfsjg qbcgivbxcm (ayuraxkgbm ) View more | Positive | 07 Oct 2021 | |||
Placebo | hnghxaywjb(mjpsstakzh) = awgdnjcmfv qbcgivbxcm (ayuraxkgbm ) View more |