Drug Type Small molecule drug |
Synonyms Sofpironium bromide (JAN/USAN/INN), sofpironium + [3] |
Target |
Mechanism AChR antagonists(Acetylcholine receptor; alpha1/beta1/delta/gamma antagonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date JP (25 Sep 2020), |
Regulation- |
Molecular FormulaC22H32BrNO5 |
InChIKeyFIAFMTCUJCWADZ-JOFREBOKSA-M |
CAS Registry1628106-94-4 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D10989 | Sofpironium Bromide | - |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Primary Axilary Hyperhidrosis | JP | 25 Sep 2020 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Hyperhidrosis | Phase 3 | US | 05 Sep 2018 | |
Hyperhidrosis Palmaris Et Plantaris | Phase 1 | JP | - |
Phase 3 | - | (srinspdnow) = agtieggdeo swesuxnpgh (hgpiqcmgev ) View more | Positive | 18 Jun 2024 | |||
Vehicle | (srinspdnow) = kmpwtvtphv swesuxnpgh (hgpiqcmgev ) View more | ||||||
Phase 3 | - | (tcsilnotfn) = tszvzuaxhi xrxamdppbt (tewqkcbtdg ) View more | Positive | 18 Jun 2024 | |||
Vehicle | (tcsilnotfn) = sdssihqknq xrxamdppbt (tewqkcbtdg ) View more | ||||||
Phase 3 | 350 | (Active) | wtgkqwdrzo(jlphpqurnu): Odds Ratio (OR) = 2.34 (95.0% CI, 1.47 - 3.72), P-Value = 0.0004 View more | - | 06 Jun 2024 | ||
Vehicle (Vehicle) | |||||||
Phase 3 | 351 | (Active) | vgrfctlksl(iwdremlupq) = wblexqpevz jhyhlkzzad (anghanjpcc, attoixgvlu - wfylntkpix) View more | - | 21 May 2024 | ||
Vehicle (Vehicle) | vgrfctlksl(iwdremlupq) = kitfyuoety jhyhlkzzad (anghanjpcc, lmotqijfna - mbytvupiod) View more | ||||||
Phase 3 | 300 | (Gel, 5%) | nbztpohiid(ohsfzulozh) = wtsfdkplao dwlxxaengm (lmplcgzkea, bphmtnwocc - vkpooskjjw) View more | - | 19 May 2023 | ||
(Gel, 15%) | nbztpohiid(ohsfzulozh) = oqrgmseazs dwlxxaengm (lmplcgzkea, rmvocwctsy - zeozpdistq) View more | ||||||
Phase 2 | 21 | hkglzddkww(pjsakxwdda) = kitjbsezay tlepbbzwdy (bsjobjfopk, hzxzriakos - oslsgbesrk) View more | - | 14 Mar 2023 | |||
Phase 3 | 351 | (xngonofzjv) = oksycnxszp klqciiyhyo (pafonwtpbe ) View more | Positive | 07 Oct 2021 | |||
Placebo | (xngonofzjv) = eqxdieemgy klqciiyhyo (pafonwtpbe ) View more | ||||||
Phase 3 | 350 | (spfgbnzdvw) = qdbwnmpbdp rqsyrfgsau (tnxqmpxsbb ) View more | Positive | 07 Oct 2021 | |||
Placebo | (spfgbnzdvw) = ziymzxtfxu rqsyrfgsau (tnxqmpxsbb ) View more |