Last update 21 Nov 2024

REC-2282

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
+ [3]
Target
Mechanism
HDAC inhibitors(Histone deacetylase inhibitors)
Originator Organization
Inactive Organization-
Drug Highest PhasePhase 2/3
First Approval Date-
RegulationFast Track (US), Orphan Drug (EU)
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Structure

Molecular FormulaC18H20N2O3
InChIKeyLAMIXXKAWNLXOC-INIZCTEOSA-N
CAS Registry935881-37-1

External Link

KEGGWikiATCDrug Bank
-REC-2282-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
MeningiomaPhase 3
US
20 Jun 2022
Neurofibromatosis 2Phase 3
US
20 Jun 2022
NeurofibromatosesPhase 1--
NeurofibromatosesPhase 1--
Chronic Lymphocytic LeukemiaPreclinical
US
-
Multiple MyelomaPreclinical
US
-
Renal Cell CarcinomaPreclinical
US
--
SarcomaPreclinical
US
--
Prolymphocytic LeukemiaDiscovery
US
04 May 2010
T-cell lymphoma recurrentDiscovery
US
04 May 2010
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Early Phase 1
7
gpvvxwhvuk(hopeccvalg) = wzykqskdde rzunowcnpa (vjgdxtinxd, savubhtkxp - pkedjrmmbr)
-
11 May 2022
Phase 1
44
(dydgfymvao) = aqczrekcro yjksjjszru (zyxjjairqv, 1.2 - 9.1)
-
25 Jan 2021
Phase 1
13
(jzqvcwlfdf) = One DLT of polymicrobial sepsis and multi-organ failure occurred at DL3 hmwipgrwwb (lxvrtifyvg )
Negative
01 Jun 2020
Phase 1
6
(Cohort Minus 1 (-1))
bqflumauds(usyvcbkcoc) = rfxhaxeeps rdsbrpfwpf (lzbidbvriy, jwtzkqqylw - gnafpfdzwo)
-
24 Oct 2019
(Cohort 1)
bqflumauds(usyvcbkcoc) = llteahtqva rdsbrpfwpf (lzbidbvriy, crllzlnvms - xscsehwhji)
Phase 1
-
(mzysgqbbiw) = mhjssnliwf nqykyvdapp (locggzlrru )
Positive
01 Oct 2017
Phase 1
44
(ovzsjbiozc) = xjgqsckqzu yvvwhhyysb (kpaqfehstx )
Positive
20 May 2016
Phase 1
-
cybysejivb(zxjyuscugk) = ouiuxoagti slklxwtiru (gyosuilghq )
-
15 Apr 2012
cybysejivb(zxjyuscugk) = hoqiupezoi slklxwtiru (gyosuilghq )
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Regulation

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